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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GRIK3 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006811ion transportIEA
GO:0007196inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathwayIDA
GO:0007215glutamate signaling pathwayIDA
GO:0007216metabotropic glutamate receptor signaling pathwayIDA
GO:0007268synaptic transmissionTAS
GO:0042391regulation of membrane potentialIDA
GO:0042391regulation of membrane potentialISS
GO:0051967negative regulation of synaptic transmission, glutamatergicISS
cellular_component
GO:0005886plasma membraneIEA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIDA
GO:0016021integral to membraneIEA
GO:0030054cell junctionIEA
GO:0030424axonISS
GO:0030425dendriteISS
GO:0032839dendrite cytoplasmISS
GO:0043195terminal buttonISS
GO:0043204perikaryonISS
GO:0045202synapseIEA
GO:0045211postsynaptic membraneIEA
molecular_function
GO:0001640adenylate cyclase inhibiting metabotropic glutamate receptor activityIDA
GO:0004872receptor activityIEA
GO:0004970ionotropic glutamate receptor activityIDA
GO:0004970ionotropic glutamate receptor activityIEA
GO:0004970ionotropic glutamate receptor activityISS
GO:0005216ion channel activityIEA
GO:0005234extracellular-glutamate-gated ion channel activityIEA
GO:0008066glutamate receptor activityTAS
GO:0015277kainate selective glutamate receptor activityIDA

Protein-protein interaction details for GRIK3 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PICK1Two-hybridphysical11891216
GRIP1Two-hybridphysical11891216
PICK1Reconstituted Complexphysical11891216
GRIP1Reconstituted Complexphysical11891216
SDCBPReconstituted Complexphysical11891216
GRIK5Affinity Capture-Westernphysical9466455