Entrez gene ID | | 3172 |
Official gene symbol | | HNF4A |
Full name | | hepatocyte nuclear factor 4, alpha |
Aliases | | ,FLJ39654,HNF4,HNF4a7,HNF4a8,HNF4a9,HNF4alpha,MODY,MODY1,NR2A1,NR2A21,TCF,TCF14, |
Gene summary | | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q12-q13.1 |
Gene position | | 42984441 - 43060030 Map Viewer |
Gene orientation | | plus |
Gene size | | 75590 bp |
Gene sequence |
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OMIM ID | | 600281 |
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