Entrez gene ID | | 330 |
Official gene symbol | | BIRC3 |
Full name | | baculoviral IAP repeat-containing 3 |
Aliases | | ,AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49,c-IAP2, |
Gene summary | | The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q22 |
Gene position | | 102188194 - 102208465 Map Viewer |
Gene orientation | | plus |
Gene size | | 20272 bp |
Gene sequence |
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OMIM ID | | 601721 |
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