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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BIRC3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID330
Official gene symbolBIRC3
Full namebaculoviral IAP repeat-containing 3
Aliases,AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49,c-IAP2,
Gene summaryThe protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q22
Gene position102188194 - 102208465  Map Viewer
Gene orientationplus
Gene size20272 bp
Gene sequence
OMIM ID601721