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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BIRC3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006916 anti-apoptosis TAS GO:0007166 cell surface receptor linked signaling pathway TAS GO:0016567 protein ubiquitination IDA GO:0042981 regulation of apoptosis IEA cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA molecular_function GO:0004842 ubiquitin-protein ligase activity IDA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for BIRC3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HTRA2 Reconstituted Complex physical 12865429 CASP9 Reconstituted Complex physical 9545235 CASP9 Affinity Capture-Western physical 9545235 RIPK2 Affinity Capture-Western physical 9705938 DIABLO Affinity Capture-Western physical 10929712 TRAF2 Two-hybrid physical 8643514 TRAF1 Reconstituted Complex physical 9384571 TRAF2 Reconstituted Complex physical 9384571 CASP3 Reconstituted Complex physical 9384571 CASP7 Reconstituted Complex physical 9384571 BCL10 Affinity Capture-Western physical 10753917 TRAF2 Affinity Capture-Western physical 10753917 TRAF2 Affinity Capture-Western physical 10753917 TRAF2 Reconstituted Complex physical 11907583 BIRC3 Biochemical Activity physical 11907583 TRAF1 Reconstituted Complex physical 11907583 RAF1 Reconstituted Complex physical 19011619 TNFRSF1A Affinity Capture-Western physical 18939944 BIRC3 Co-crystal Structure physical 18784070 UBE2D2 Co-crystal Structure physical 18784070 UBE2D2 Reconstituted Complex physical 18784070 UBC Affinity Capture-Western physical 18570872 RIPK1 Affinity Capture-Western physical 18570872 RIPK1 Biochemical Activity physical 18570872 XAF1 Affinity Capture-Western physical 17613533 BCL10 Affinity Capture-Western physical 16775419 UBE2N Two-hybrid physical 19690564 TRAF2 Affinity Capture-MS physical 20562859 TRAF2 Reconstituted Complex physical 16282325 BIRC5 Reconstituted Complex physical 15218035 DIABLO Reconstituted Complex physical 14960576 UBC Affinity Capture-Western physical 12525502 UBE2L3 Affinity Capture-Western physical 12525502 UBE2D1 Affinity Capture-Western physical 12525502 UBE2D3 Affinity Capture-Western physical 12525502 DIABLO Biochemical Activity physical 12525502 RIPK2 Reconstituted Complex physical 19464198 RIPK2 Affinity Capture-Western physical 19464198 BIRC3 Biochemical Activity physical 19810754 TRAF2 Affinity Capture-Western physical 19815541 TNFRSF1A Affinity Capture-Western physical 19815541 UBE2I Two-hybrid physical 21113135 UBE2D1 Two-hybrid physical 21113135 UBE2D2 Two-hybrid physical 21113135 UBE2D3 Two-hybrid physical 21113135 UBE2Q2 Two-hybrid physical 21113135 UBE2I Two-hybrid physical 21113135 BIRC3 Two-hybrid physical 21113135 BIRC3 Biochemical Activity physical 21113135 RIPK1 Biochemical Activity physical 21113135 UBC Reconstituted Complex physical 21113135 TRAF3 Affinity Capture-Western physical 20097753 TRAF6 Affinity Capture-Western physical 20097753 MAVS Affinity Capture-Western physical 20097753 RIPK1 Reconstituted Complex physical 21931591 RIPK2 Reconstituted Complex physical 21931591 RIPK3 Reconstituted Complex physical 21931591 RIPK4 Reconstituted Complex physical 21931591 RIPK1 Affinity Capture-Western physical 21931591 RIPK2 Affinity Capture-Western physical 21931591 RIPK3 Affinity Capture-Western physical 21931591 RIPK4 Affinity Capture-Western physical 21931591 RIPK1 Biochemical Activity physical 21931591 RIPK2 Biochemical Activity physical 21931591 RIPK3 Biochemical Activity physical 21931591 RIPK4 Biochemical Activity physical 21931591 UBXN1 Affinity Capture-MS physical 18775313 USP19 Affinity Capture-Western physical 21849505 USP19 Affinity Capture-Western physical 21849505 USP19 Biochemical Activity physical 21849505 TRAF2 Affinity Capture-Western physical 21331077 TRIM32 Affinity Capture-Western physical 21628460