Entrez gene ID | | 3558 |
Official gene symbol | | IL2 |
Full name | | interleukin 2 |
Aliases | | ,IL-2,TCGF,lymphokine, |
Gene summary | | The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q26-q27 |
Gene position | | 123377650 - 123372625 Map Viewer |
Gene orientation | | minus |
Gene size | | 5026 bp |
Gene sequence |
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OMIM ID | | 147680 |
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