Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001933negative regulation of protein phosphorylationIEA
GO:0001934positive regulation of protein phosphorylationIEA
GO:0002903negative regulation of B cell apoptosisIDA
GO:0006916anti-apoptosisTAS
GO:0006955immune responseTAS
GO:0007155cell adhesionTAS
GO:0007204elevation of cytosolic calcium ion concentrationIEA
GO:0007205activation of protein kinase C activity by G-protein coupled receptor protein signaling pathwayIEA
GO:0007267cell-cell signalingTAS
GO:0008284positive regulation of cell proliferationTAS
GO:0030101natural killer cell activationTAS
GO:0030217T cell differentiationTAS
GO:0030307positive regulation of cell growthTAS
GO:0030890positive regulation of B cell proliferationIDA
GO:0032740positive regulation of interleukin-17 productionIDA
GO:0034105positive regulation of tissue remodelingIC
GO:0042104positive regulation of activated T cell proliferationIDA
GO:0042327positive regulation of phosphorylationTAS
GO:0042523positive regulation of tyrosine phosphorylation of Stat5 proteinIDA
GO:0045591positive regulation of regulatory T cell differentiationIEA
GO:0045822negative regulation of heart contractionIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0046013regulation of T cell homeostatic proliferationIEA
GO:0048304positive regulation of isotype switching to IgG isotypesIEA
GO:0050672negative regulation of lymphocyte proliferationIEA
GO:0050728negative regulation of inflammatory responseIEA
GO:0050729positive regulation of inflammatory responseIC
GO:0051024positive regulation of immunoglobulin secretionIEA
cellular_component
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceTAS
molecular_function
GO:0005125cytokine activityIDA
GO:0005134interleukin-2 receptor bindingIDA
GO:0005134interleukin-2 receptor bindingTAS
GO:0008083growth factor activityTAS
GO:0019209kinase activator activityTAS
GO:0030246carbohydrate bindingIEA
GO:0031851kappa-type opioid receptor bindingIEA
GO:0043208glycosphingolipid bindingIEA

Protein-protein interaction details for IL2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
DGKACo-localizationphysical8626603
IL21RAffinity Capture-Westernphysical11418623