Entrez gene ID | | 3611 |
Official gene symbol | | ILK |
Full name | | integrin-linked kinase |
Aliases | | ,DKFZp686F1765,P59, |
Gene summary | | Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.5-p15.4 |
Gene position | | 6624964 - 6632101 Map Viewer |
Gene orientation | | plus |
Gene size | | 7138 bp |
Gene sequence |
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OMIM ID | | 602366 |
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