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Gene information for ILK (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3611
Official gene symbolILK
Full nameintegrin-linked kinase
Aliases,DKFZp686F1765,P59,
Gene summaryTransduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15.5-p15.4
Gene position6624964 - 6632101  Map Viewer
Gene orientationplus
Gene size7138 bp
Gene sequence
OMIM ID602366