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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ILK (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001558 regulation of cell growth IEA GO:0001658 branching involved in ureteric bud morphogenesis IEA GO:0001954 positive regulation of cell-matrix adhesion IEA GO:0006468 protein phosphorylation IDA GO:0006469 negative regulation of protein kinase activity IEA GO:0007050 cell cycle arrest IEA GO:0007160 cell-matrix adhesion NAS GO:0007229 integrin-mediated signaling pathway IDA GO:0007229 integrin-mediated signaling pathway IEA GO:0007229 integrin-mediated signaling pathway NAS GO:0007569 cell aging IEA GO:0008283 cell proliferation NAS GO:0008284 positive regulation of cell proliferation IEA GO:0009966 regulation of signal transduction IEA GO:0010667 negative regulation of cardiac muscle cell apoptosis IEA GO:0014912 negative regulation of smooth muscle cell migration IEA GO:0018105 peptidyl-serine phosphorylation IEA GO:0030335 positive regulation of cell migration IEA GO:0030513 positive regulation of BMP signaling pathway IEA GO:0032288 myelin assembly IEA GO:0032956 regulation of actin cytoskeleton organization IEA GO:0034329 cell junction assembly TAS GO:0034446 substrate adhesion-dependent cell spreading IEA GO:0034446 substrate adhesion-dependent cell spreading IMP GO:0042327 positive regulation of phosphorylation IMP GO:0043206 fibril organization IEA GO:0043406 positive regulation of MAP kinase activity IEA GO:0043410 positive regulation of MAPKKK cascade IEA GO:0043524 negative regulation of neuron apoptosis IEA GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IEA GO:0045663 positive regulation of myoblast differentiation IEA GO:0045669 positive regulation of osteoblast differentiation IEA GO:0045773 positive regulation of axon extension IEA GO:0045893 positive regulation of transcription, DNA-dependent IMP GO:0048662 negative regulation of smooth muscle cell proliferation IEA GO:0048812 neuron projection morphogenesis IEA GO:0050775 positive regulation of dendrite morphogenesis IEA GO:0051291 protein heterooligomerization IEA GO:0051897 positive regulation of protein kinase B signaling cascade IEA GO:0090263 positive regulation of canonical Wnt receptor signaling pathway IMP cellular_component GO:0001725 stress fiber IEA GO:0005737 cytoplasm IEA GO:0005737 cytoplasm NAS GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA GO:0005911 cell-cell junction IEA GO:0005925 focal adhesion IEA GO:0030424 axon IEA GO:0043025 neuronal cell body IEA GO:0043034 costamere IEA GO:0043195 terminal button IEA GO:0043198 dendritic shaft IEA GO:0043234 protein complex IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IEA GO:0004674 protein serine/threonine kinase activity IDA GO:0004674 protein serine/threonine kinase activity IEA GO:0004871 signal transducer activity IEA GO:0005178 integrin binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding NAS GO:0017124 SH3 domain binding IEA GO:0019901 protein kinase binding IPI

Protein-protein interaction details for ILK (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ILKAP Two-hybrid physical 11331582 LIMS1 Two-hybrid physical 10022929 PARVA Two-hybrid physical 16189514 ACP6 Affinity Capture-MS physical 17353931 ACP6 Affinity Capture-MS physical 17353931 HEATR1 Affinity Capture-MS physical 17353931 OTUD4 Affinity Capture-MS physical 17353931 FANCI Affinity Capture-MS physical 17353931 GEMIN4 Affinity Capture-MS physical 17353931 DDX3X Affinity Capture-MS physical 17353931 MMS19 Affinity Capture-MS physical 17353931 MYO1D Affinity Capture-MS physical 17353931 HEATR2 Affinity Capture-MS physical 17353931 RSU1 Affinity Capture-MS physical 17353931 PARVB Affinity Capture-MS physical 17353931 AUP1 Affinity Capture-MS physical 17353931 NOC2L Affinity Capture-MS physical 17353931 IGF2BP1 Affinity Capture-MS physical 17353931 COPG Affinity Capture-MS physical 17353931 S100A9 Affinity Capture-MS physical 17353931 EWSR1 Affinity Capture-MS physical 17353931 PUF60 Affinity Capture-MS physical 17353931 MARS Affinity Capture-MS physical 17353931 PRPSAP1 Affinity Capture-MS physical 17353931 DHX36 Affinity Capture-MS physical 17353931 COPB2 Affinity Capture-MS physical 17353931 ERH Affinity Capture-MS physical 17353931 HSPB1 Affinity Capture-MS physical 17353931 ILK Biochemical Activity physical 8538749 ITGA5 Affinity Capture-Western physical 8538749 ITGB1 Affinity Capture-Western physical 8538749 VTNR Affinity Capture-Western physical 8538749 ILKAP Affinity Capture-Western physical 11331582 ITGB3 Affinity Capture-Western physical 12372433 PXN Reconstituted Complex physical 11304546 AKT1 Affinity Capture-Western physical 11825911 AKT1 Biochemical Activity physical 9736715 LIMS1 Reconstituted Complex physical 10022929 NCK2 Reconstituted Complex physical 10022929 LIMS1 Affinity Capture-Western physical 12167643 LIMS2 Affinity Capture-Western physical 12167643 LIMS2 Affinity Capture-Western physical 12167643 AKT1 Affinity Capture-Western physical 11313365 PDPK1 Affinity Capture-Western physical 11313365 RPL13 Two-hybrid physical 21900206 ZBTB48 Two-hybrid physical 21900206 SHC1 Two-hybrid physical 21900206 MIPEP Two-hybrid physical 21900206 ZNF579 Two-hybrid physical 21900206 SERPINA4 Two-hybrid physical 21900206 ZNF746 Two-hybrid physical 21900206 SNRNP35 Two-hybrid physical 21900206 CKB Two-hybrid physical 21900206 RNF19A Two-hybrid physical 21900206 ZNF133 Two-hybrid physical 21900206 ZNF205 Two-hybrid physical 21900206 UBC Affinity Capture-MS physical 21987572