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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDX1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3651 Official gene symbol PDX1 Full name pancreatic and duodenal homeobox 1 Aliases ,GSF,IDX-1,IPF1,IUF1,MODY4,PDX-1,STF-1, Gene summary The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq] Location Chromosome: 13   Locus: 13q12.1 Gene position 28494168 - 28500451  Map Viewer Gene orientation plus Gene size 6284 bp Gene sequence >PDX1:9474168..9480451:Length=6284 GGGTGGCGCCGGGAGTGGGAACGCCACACAGTGCCAAATCCCCGGCTCCAGCTCCCGACT CCCGGCTCCCGGCTCCCGGCTCCCGGTGCCCAATCCCGGGCCGCAGCCATGAACGGCGAG GAGCAGTACTACGCGGCCACGCAGCTTTACAAGGACCCATGCGCGTTCCAGCGAGGCCCG GCGCCGGAGTTCAGCGCCAGCCCCCCTGCGTGCCTGTACATGGGCCGCCAGCCCCCGCCG CCGCCGCCGCACCCGTTCCCTGGCGCCCTGGGCGCGCTGGAGCAGGGCAGCCCCCCGGAC ATCTCCCCGTACGAGGTGCCCCCCCTCGCCGACGACCCCGCGGTGGCGCACCTTCACCAC CACCTCCCGGCTCAGCTCGCGCTCCCCCACCCGCCCGCCGGGCCCTTCCCGGAGGGAGCC GAGCCGGGCGTCCTGGAGGAGCCCAACCGCGTCCAGCTGCCTTTCCCATGGATGAAGTCT ACCAAAGCTCACGCGTGGAAAGGCCAGTGGGCAGGTAAGCCTGGCTCCCCACCCCTTTCT CCTTTCCGGTTCTCACCCGGCCGCCTTACCTCCAAGCGCTCCCAGGAGCCTTCTCTCTGT TCCCGGCGCCTTGGATTATCCCGGGTCGGACTAAACTACATCAGGGAGCTACCGAGCCCA TCCCTCACAGCAGTGCTTCTCTAGTCCAGTTTGAAGCATCTTTCCCACCCAGCTCTCCTG GGAGTGTACACTCCTTCCTTCCCTGTTCGCTGAGCCCATCTTCGCCCCAGGAGCCCGCGC TCCCAGCGCCATCCTTAGAGAGCCGAGGCTGAGTCCTGCTCAGGGCTTCGGACACTACAG ATCCTCCTCCAGCAGGGGATCCGGGAACCCAGGACTCCTTGGTAGTGCACATCGAGGAAG CCGAGTAGGGACATGGGTGCCTCGGACCCAGGCCCCAGATCGCCTTCGGAGCCCCGGAGC CCCTCACTTCCCGCGCTTCGTTAAGGAAGGGCAGGCATCTAGGGGCGCCAGGTAGGTGCA GAAAGGCAGGGAGGGAAAGGAAACTGCACCCAACCCAGCAGTGTCCGGCTGCCCTGGTTG TGGAAACAGGATAGGAGTAAAGAGGAAGGGGCTGGGGCAAGGCGGGGGCTCACCGCGAGG CTGAAAGCCGGCCTCTCAACGTCAGAGCCTGGCAGCTAGGAGAGCAATCTGAGAAGCGAA TTCGTTTTTCACCAACCGAAAGCAATTGAAGCTGTCTCCCCGCACCGCTTCCCAGGAAGT AATTTTTCAGGAGATGGGCGCTCCCTGCCTAGCTGGTGGGGAGGCGAGAGGCCTGGTTCC TGCGGCCCTCCGCGCCGGCAGAGAACAGAAGGTCTTTCCCGGAGCCGGGAGCCGGAGGCA CGGGGTAGCCCCCGGGTCCTTTGCGGCCCCGCGCGAGCGGCAAGTTCCGGCGCGGCCTGT GTCGTCGCCGCTACTCACTGTCATCGCTGCCGTGCCTCAGCCACTTCTGGTCACACCTGC ACCGCAAATAGTTGCCTTTTCCTTTCAACTGGCAGCCGGGAGTAGGGGGAAGCAGCTCGA GCCGGCGTCCCCCGGCCCACCCCGAAAATCCTCAGCGCCCATCTGCGGGGTCTGGCCAGC CCTGCCTGACACTGACCCCAGGCGCAGCCAGGAGGGGCTTTGTGCGGGAGAGGGAGGGGG ACCCCAGCTTGCCTGGGGTCCACGGGACTCTCTTCTTCCTAGTTCACTTTCTTGCTAAGG CGAAGGTCCTGAGGCAGGACGAGGGCTGAACTGCGCTGCAATCGTCCCCACCTCCAGCGA AACCCAGTTGACAGGGGCGCCAGAAGCTGCCGCGGCGCCTCTGCAAATTTATCCAGCTCG CGCAGCCCGGGCCAAAGGCCTTGAAGTCTCCGGAAATGCGGGGTTCTTAGGAGGCGGGAG GACAGTCCCTCGAACAAAGGTGGGGGGCTCCTCGTCCTCACCCAGTTTTCTTCCAGGGCT GCCTCCCCTCCAGACCTCTCTTCTGGCCTCCTAGGCCCTCGGAGCTCCTGCTTTCCCACC CTGGGCCTTCCTCAGGAAATGGGCGACATCAGGGTCCCGAAAGAGGATTTGTGAGGTGGA GTAACTTCCCTATCCCAACCCAAGGGGTGATACCTCTGCTCTGGAGGACTTGGGCTTAGG CTGACCCAAGAAGCCAGAAAGTAAAACCAGAAGGCAAATCAGCAGCCTTGGCGAGGGTTC GGGGACCCAAGGAGGGCGACACTCTCGGGCTGGAGTTGGCCCCAGGCCTTTGCTGGCGCC CTCTAACCCGCTGCATGCTCGACTCTCGGGGAAGGAGACGACCTCCCCTCTCTTCCCCTG GAAGCCGTCTGCGGGGCCGGCTGCTATCCCCGCGTTCCTCTAGGGGAAACTTCGATGGAG CCGAAATTCAAAAATTGCAAACCCACCTGCCCCTGGGAAGAGCGAAGTGACAAAAGGGCT CTCACTGGCAGTACGAATCTGAATGCTAATGACAACAGAGGTTTTGAAAAACATTGACCC CCAAATGCTTCAGCAGCGCTGTCCAGCTGGCACCTAAACTGCATCACTCTGCGCCTTGGG GAAGGGCCCAGGCTTGGCGACCTTGACCTTTTCCCACCATCCTCAACCTCCACCCCTGCC GCGTCGCGCTGAGCACAGGTCCCCCGGGAATAGTGCACCCCAGGAAGTCTCTCCCTGAGC AGTCTCTCGCAGGGACTTCACGAAGCCCTCTCGCAGGGACTATACGAAGCCCGCAGCCTA AGGCAGGAACCCAGAGACATGTCGGTTTAATGTAAAAACTTTGGAGAGCCTTTCAAAATG TTTATTGAAGGCCCGTCTCGCTTCTCTCCCAGGCGTGGGATGCCAGGTAGATTCGGGGAT GCCCCCAGGGAGTAGAACTCTCCCTGGACTAGGGTTTGAGCCTCTGCTTCAGCTTCTGGC GCCTCTTCTCGACCTGGGGGGAAACCCAGTAGGGTTCCATCGCGAAATTAAACCCGCCCC CAACACACACACACTCGCCTTTCAATTCCTTAAGGCTTAGCCAACATTCACAGGAGAAAT GTCCCCTGCCTTTGCTCTAAGACAAGCCTCTCCCCGGAACTTTGGTGGAACTTCCCGCGC CAGCGTCCACAGCCTGGGTGCAGTCAGTATTTTCCACAGAAAAGAAAAGATTGGGACCTG GCTGAGCGCAGCGGCAAACAGTGAATGTGGGTCTCCAACCTCCTGGGCCAGGGCGTCCTG TTGCCTCTTGGAGACACGAGAGGCTTGTTTCTGCACCACTACCACCTCCTCCGTAGGGCT GTCGGTTCTGCAGCTGGGCTAGGGCCCCTGTGTCTCCCCTCAACACCTCTGAGGGCATTT GGGATCCAGGGCGTAGAGTCTGGAGCTGCCAGAGTTCTGCCCTGGCCAACGTGACCCCCA GAACAATATTCCTTCACTTCGCGGGCAGAAGTCCGGCTGAAGTTAAAACAATTATGGAGA ATTTGCTGGCTCTCAGGTTGGGACTAATTACGATATAACTATAGAGAGAGGAAACACATG GTCAGATATAACAAAATGTGTCACAGTCTCCATTAGCACAAAGATTTTCAAACTGCAGGT TGCACCCATTCGCAGGTCATAAAATCAATTTACTAGGTTGAGATTAGTATTTTTTAAACG AAATAGCAGATAATGGAGAGAAAAGTAGATAGCATCATACGTGGTAAACGTTTGTTTTAT GTCCTTAAGATTTGTCAGTATAACTGACCTGCAGTGTCCGTGTGTGAACTACACAACGAT CCGAAATGTATTTCTCACATTTGTGGGTCACCATCAGGAGGTTTTTTTTAGCCCTGGATT AAAGGCGTTTTATTGCCTTTGTAGGATCCAGCCGGTTTAACTATTATATACATTTAAATC AACATCAATCAGTTGATTAACACCGATTATATGAGCGCATTCAAGGACCACTCATTGGCA GAGCCAAGCTTAGGCTCACGGCGAGAGCTGACTCGAGTTTGGTCTCCAATAAAAAGGCTA TCTTTATTAGGAAGGGCTTGAGTTACTAGGGAAGAGCTTCGCGCGCCTACACTAGGCGCT GAAATGGGATGCTGGGGCTTGGTGGCTCCGGCGGGAGCAGCTGGTAGGGCTAGGGCTCCC TGGCCCCCCTTGAAGGGGTTGGGCTGCGTGGGTGGGGGCTGTGCGGGGCTCCGGGGGCCA CACTCACGCCCTGTGTCGCCCGCAGGCGGCGCCTACGCTGCGGAGCCGGAGGAGAACAAG CGGACGCGCACGGCCTACACGCGCGCACAGCTGCTAGAGCTGGAGAAGGAGTTCCTATTC AACAAGTACATCTCACGGCCGCGCCGGGTGGAGCTGGCTGTCATGTTGAACTTGACCGAG AGACACATCAAGATCTGGTTCCAAAACCGCCGCATGAAGTGGAAAAAGGAGGAGGACAAG AAGCGCGGCGGCGGGACAGCTGTCGGGGGTGGCGGGGTCGCGGAGCCTGAGCAGGACTGC GCCGTGACCTCCGGCGAGGAGCTTCTGGCGCTGCCGCCGCCGCCGCCCCCCGGAGGTGCT GTGCCGCCCGCTGCCCCCGTTGCCGCCCGAGAGGGCCGCCTGCCGCCTGGCCTTAGCGCG TCGCCACAGCCCTCCAGCGTCGCGCCTCGGCGGCCGCAGGAACCACGATGAGAGGCAGGA GCTGCTCCTGGCTGAGGGGCTTCAACCACTCGCCGAGGAGGAGCAGAGGGCCTAGGAGGA CCCCGGGCGTGGACCACCCGCCCTGGCAGTTGAATGGGGCGGCAATTGCGGGGCCCACCT TAGACCGAAGGGGAAAACCCGCTCTCTCAGGCGCATGTGCCAGTTGGGGCCCCGCGGGTA GATGCCGGCAGGCCTTCCGGAAGAAAAAGAGCCATTGGTTTTTGTAGTATTGGGGCCCTC TTTTAGTGATACTGGATTGGCGTTGTTTGTGGCTGTTGCGCACATCCCTGCCCTCCTACA GCACTCCACCTTGGGACCTGTTTAGAGAAGCCGGCTCTTCAAAGACAATGGAAACTGTAC CATACACATTGGAAGGCTCCCTAACACACACAGCGGGGAAGCTGGGCCGAGTACCTTAAT CTGCCATAAAGCCATTCTTACTCGGGCGACCCCTTTAAGTTTAGAAATAATTGAAAGGAA ATGTTTGAGTTTTCAAAGATCCCGTGAAATTGATGCCAGTGGAATACAGTGAGTCCTCCT CTTCCTCCTCCTCCTCTTCCCCCTCCCCTTCCTCCTCCTCCTCTTCTTTTCCCTCCTCTT CCTCTTCCTCCTGCTCTCCTTTCCTCCCCCTCCTCTTTTCCCTCCTCTTCCTCTTCCTCC TGCTCTCCTTTCCTCCCCCTCCTCTTTCTCCTCCTCCTCCTCTTCTTCCCCCTCCTCTCC CTCCTCCTCTTCTTCCCCCTCCTCTCCCTCCTCCTCTTCTTCTCCCTCCTCTTCCTCTTC CTCCTCTTCCACGTGCTCTCCTTTCCTCCCCCTCCTCTTGCTCCCCTTCTTCCCCGTCCT CTTCCTCCTCCTCCTCTTCTTCTCCCTCCTCTTCCTCCTCCTCTTTCTTCCTGACCTCTT TCTTTCTCCTCCTCCTCCTTCTACCTCCCCTTCTCATCCCTCCTCTTCCTCTTCTCTAGC TGCACACTTCACTACTGCACATCTTATAACTTGCACCCCTTTCTTCTGAGGAAGAGAACA TCTTGCAAGGCAGGGCGAGCAGCGGCAGGGCTGGCTTAGGAGCAGTGCAAGAGTCCCTGT GCTCCAGTTCCACACTGCTGGCAGGGAAGGCAAGGGGGGACGGGCCTGGATCTGGGGGTG AGGGAGAAAGATGGACCCCTGGGTGACCACTAAACCAAAGATATTCGGAACTTTCTATTT AGGATGTGGACGTAATTCCTGTTCCGAGGTAGAGGCTGTGCTGAAGACAAGCACAGTGGC CTGGTGCGCCTTGGAAACCAACAACTATTCACGAGCCAGTATGACCTTCACATCTTTAGA AATTATGAAAACGTATGTGATTGGAGGGTTTGGAAAACCAGTTATCTTATTTAACATTTT AAAAATTACCTAACAGTTATTTACAAACAGGTCTGTGCATCCCAGGTCTGTCTTCTTTTC AAGGTCTGGGCCTTGTGCTCGGGTTATGTTTGTGGGAAATGCTTAATAAATACTGATAAT ATGGGAAGAGATGAAAACTGATTCTCCTCACTTTGTTTCAAACCTTTCTGGCAGTGGGAT GATTCGAATTCACTTTTAAAATTAAATTAGCGTGTTTTGTTTTG OMIM ID 600733