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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PDX1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0001889liver developmentIEA
GO:0003309type B pancreatic cell differentiationIDA
GO:0003309type B pancreatic cell differentiationISS
GO:0006006glucose metabolic processIEA
GO:0006091generation of precursor metabolites and energyTAS
GO:0006355regulation of transcription, DNA-dependentTAS
GO:0006366transcription from RNA polymerase II promoterTAS
GO:0007263nitric oxide mediated signal transductionIDA
GO:0007275multicellular organismal developmentIEA
GO:0008284positive regulation of cell proliferationIEA
GO:0008285negative regulation of cell proliferationIEA
GO:0009887organ morphogenesisTAS
GO:0016331morphogenesis of embryonic epitheliumIEA
GO:0030073insulin secretionIDA
GO:0031017exocrine pancreas developmentIEA
GO:0031018endocrine pancreas developmentTAS
GO:0042593glucose homeostasisIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterISS
GO:0048565digestive tract developmentIEA
GO:0051594detection of glucoseISS
cellular_component
GO:0005634nucleusIEA
GO:0044424intracellular partIEA
molecular_function
GO:0003682chromatin bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityTAS
GO:0043565sequence-specific DNA bindingIEA

Protein-protein interaction details for PDX1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
MAFAAffinity Capture-Westernphysical15665000
MAFAReconstituted Complexphysical15665000
ALKAffinity Capture-MSphysical14968112
XRCC6Affinity Capture-Westernphysical16166097
XRCC5Affinity Capture-Westernphysical16166097
XRCC6Reconstituted Complexphysical16166097
XRCC5Reconstituted Complexphysical16166097
PRKDCBiochemical Activityphysical16166097
PBX1Reconstituted Complexphysical11279116