Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for PDX1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IEA
GO:0001889
liver development
IEA
GO:0003309
type B pancreatic cell differentiation
IDA
GO:0003309
type B pancreatic cell differentiation
ISS
GO:0006006
glucose metabolic process
IEA
GO:0006091
generation of precursor metabolites and energy
TAS
GO:0006355
regulation of transcription, DNA-dependent
TAS
GO:0006366
transcription from RNA polymerase II promoter
TAS
GO:0007263
nitric oxide mediated signal transduction
IDA
GO:0007275
multicellular organismal development
IEA
GO:0008284
positive regulation of cell proliferation
IEA
GO:0008285
negative regulation of cell proliferation
IEA
GO:0009887
organ morphogenesis
TAS
GO:0016331
morphogenesis of embryonic epithelium
IEA
GO:0030073
insulin secretion
IDA
GO:0031017
exocrine pancreas development
IEA
GO:0031018
endocrine pancreas development
TAS
GO:0042593
glucose homeostasis
IEA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISS
GO:0048565
digestive tract development
IEA
GO:0051594
detection of glucose
ISS
cellular_component
GO:0005634
nucleus
IEA
GO:0044424
intracellular part
IEA
molecular_function
GO:0003682
chromatin binding
IEA
GO:0003700
sequence-specific DNA binding transcription factor activity
TAS
GO:0043565
sequence-specific DNA binding
IEA
Protein-protein interaction details for PDX1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
MAFA
Affinity Capture-Western
physical
15665000
MAFA
Reconstituted Complex
physical
15665000
ALK
Affinity Capture-MS
physical
14968112
XRCC6
Affinity Capture-Western
physical
16166097
XRCC5
Affinity Capture-Western
physical
16166097
XRCC6
Reconstituted Complex
physical
16166097
XRCC5
Reconstituted Complex
physical
16166097
PRKDC
Biochemical Activity
physical
16166097
PBX1
Reconstituted Complex
physical
11279116