Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRF1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3659
Official gene symbolIRF1
Full nameinterferon regulatory factor 1
Aliases,IRF-1,MAR,
Gene summaryIRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q31.1
Gene position131826465 - 131817301  Map Viewer
Gene orientationminus
Gene size9165 bp
Gene sequence
OMIM ID147575