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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRF4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3662 Official gene symbol IRF4 Full name interferon regulatory factor 4 Aliases ,LSIRF,MUM1, Gene summary The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] Location Chromosome: 6   Locus: 6p25-p23 Gene position 391752 - 411443  Map Viewer Gene orientation plus Gene size 19692 bp Gene sequence >IRF4:331752..351443:Length=19692 AGTTTCACCGCTCGATCTTGGGACCCACCGCTGCCCTCAGCTCCGAGTCCAGGGCGAGGT AAGGGCTGGAGTCGGGCAGGAGGAGGGGTGTGAGGCTGATACCAGAGAGGACCCGGAGCG CGAACCAGAGGTTCGACCTCCAGGGCAGCGCAGGGTACCCCGGCTTCGGAGCGGGAAGGG AGCGCGCCCCGTCCTGGAGCTCCGACTCCCACCCCATCTGCGCTGAGCCGGAGGCGCTGG TTTGGGCTCCAAGGCCCGCCTCCTTGGCTCTGCCCGAGCCTCCCCGCCTGCCCTCCGCGC TCCTGCGACGGGGTCGCCACAAGCTGGACGGGATGAGCTAACCGGACTGTCGGGGCCCCA GGAGTGGCTGAGGCGGGGCCGTCCAAGGCACCCACACAAGACGGCACAACTGCCTGCGAG AAACAGGCCCGGCCCTGTGGACCCCAATCCGAGGCTCCTTCCCCTGCTCTTCGTTCCTAA GGGGCCCAAGCTCACGGCGGCCTCCGGCGCGGTGCTCACCCGCTGGCGCAGGAGGAGGAG GAGCTCCACATTTGGGTCGCTCCGAGCCTTGCGTGCGGTGGCCTAGCCGGCCTGGCGCGG TCCCTGCCTCCCAGGCTCCGCAGCTGTCGTCGCCCTCTCCCGCGCCCTCCCCGCCTCCGC TCTCCCGGGCCTGCTCCGGGGTCCGGCGGACGCTCTGCGCGCGGAATCCCCCGTACTGGG GCTGCAGCCCCCGCGTCTGCGCCACTTGTCGTTTGCAGAGCCCACTTAGTGCGCGCTAGC TGGGCAGGGATAGGGGTCCTATTCGGGGCGAAGGGTCTGGATGCGAGCAGAGAAAGCGGA GGGTGGAGGAACCCGGGGCTGCGCCCCTGGAACGCCCGGCCGCAGGCGAGGTCCTCCGCG CGTGGAGGCCGCCAGGGGAGTGGAAACTGACAGAGTCGCGGGGAAGGGGCGAGAAGCGGG TTGGGAGTGAGCGAAGGCAAGCGAGAGCTGCGAGTGAGTGCGGAAGGAGGGCCAGGAGGG GTGGCGGCTGGGTGGGGAGAGAGGGTGCAAGACGAGCGGCGCGTGTCGGGAGCCTTTGGG CTGCGGGTGCGTTACAGGAGAGCAGGCGGGTAGGAGCCTTCGCGGGGGCCGAGCTCGGAA GGCGGACGGCTGTGCCCGCCCAGGGGATGCGCCCGGGCCGGCCGCGAAGGTGCCTTCTTC CGGGGGCCCGGACGACCCTGACACGGCACGCGCGCGCTTCGCAGCCTCAAAGACTCCGGG GCCTCGTGGTCACTGGCGCAGGGGATCGGGGCGGGGTGCCCGGAGTGCGGTGCCTCGTGG CTGAAGGGCAGCTCTTCTCCCCGCAGTGCAGAGCAGAGCGGGCGGAGGACCCCGGGCGCG GGCGCGGACGGCACGCGGGGCATGAACCTGGAGGGCGGCGGCCGAGGCGGAGAGTTCGGC ATGAGCGCGGTGAGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGACCAGATCGAC AGCGGCAAGTACCCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCATCTTCCGCATCCCC TGGAAGCACGCGGGCAAGCAGGACTACAACCGCGAGGAGGACGCCGCGCTCTTCAAGGTC TCCGGCCTCGGGAGCCGGCGGGGGCGCGCCGGGGAGGGCCCAGAGACAGAGCCCGGGGTC CCCGGCGCCGCCTCCGAGGCGAGCCCAGGGGACCGCGCGGGGCGGACGGGCGGGCGGCGG AGGCATCAGGTGGCGTCGCCGGAGCCGCAGGAGGAGGAAAGGAGGCCTCGGCTCTCAGCG GGACCGCGGGGGCCGGGAGCCGGGTCCTGGGCGCGTGGAGGCTGCAGGGAAACCGCTGAA GGCCCGGCCGGGCCCGGGGAAGGGCGGCCAAAGGCTTGAGGGGTTTTGCGCGTTCGTCCG TGCGTTCTCGTTTCCACGCAAGCCTCCCGCCCTTCCTCCGGGCTCCCGTCTGCCGCCTCC GTCCGTGGGTCCCCCTCGCCCTCTCCGTGCGTCCGCGCCTGTGCCGGCGGCTGTTTTCGT CTCTCACCGCGTCTCTGTTTCTCTTTTCGCTGCTTTTCTCTCTGAGTCTCTCTCTCTCCA TGTTTTTCCTGAGGTCAGCCTCTCTTCTCGCTCCTGCTAGCTCTCTGCGGGTACTCCCAC CTCTGTCTTTCTCTTTGTGTGTCTCTGTCTCTCTCTTTCCCCCATCGCAGTGGAACTCAG GGCCTCTGTCTAGAGCTGTCTCCCTTGCCCTTTGCGCGAGTGCACACACGTGTGTCGTTG TTACGATTGTTCTCCCCTAAGGCAGTTTACCCAGAGAACTACGTGTCTGGGCCCAGCCCC CACCTGTGGGCAGAGCAGGGGAAGGGGACTTCCTCCGGGAATTTGGTCTCAATTTGCTCT CAGAGTGCCTCAGCTGTGCTGCCATCCAGATGTCTCCTGTGGGTGACAGCTCACACCACA GCTGTCCTTAGTCCTAGGCAAGCTCACTCAGACACTGGGTGGGTAGAGCCCCCTCAAGGA ACCTCCGCATCTCACTCTACCGGTTATAAATACCCAGAAAATGTGTCTTCAACTTGGCAG TGATAGGGTCCAAGATGGAAAATCATTTTCCTAGAGCATAGCTGGGGTCTTTCAGTTTAC GTTCTGAGCAACGGTGTAAATCTGAAGGACCTATGCGCCATTCTTTCTTTTAGAAATACA ATTTCAAGATTCCTTATAAAATATCTGTATTTTGGGTTTAGCATGGTGGCTCACACCTGT AATCCCAGCACTTTGGGAAGATGAGGTGGAAGGATGCCTATGCAACATAGTGAGACCCTG CCTCTGCAAAAAATAATAATTAAAAAAATTAGCCAGGCATGGTGGTGAACACCTGTAGGC CGAGGGCCCAGCTACTCTAGAGGCTGAGATAGGAGGACCCTAGAACTCAGGAGTTCGATG CTGCGGTGAGCTATCATCGTGCCACTGTACTCTAGCCTGGGCAGCAGAGCAGGACTCTGA TTCCAAAAAGAAAGCTAATAAACCAGACATGTATTTTGACTTTTCGTTCTCTTCATTCTT TCCCACCAGGCTTGGGCACTGTTTAAAGGAAAGTTCCGAGAAGGCATCGACAAGCCGGAC CCTCCCACCTGGAAGACGCGCCTGCGGTGCGCTTTGAACAAGAGCAATGACTTTGAGGAA CTGGTTGAGCGGAGCCAGCTGGACATCTCAGACCCGTACAAAGTGTACAGGATTGTTCCT GAGGGAGCCAAAAAAGGTAGGGGCTCTCCTGAATTTGGGTCACCTAACAGAGGCAGCCAG ATCCTTGAGGCACCTTAACTTCATTCTGAGCATCACTTTCTAGCTTTCCTTTTGTATTGC CTGCCTGCCTGCCTTCTGCCTCACAGTGAAGCCCAGCCTCCTTGCCTGAGTTATGTGGGT CACAAGTTGAAATTCCTGTGGGGTTCAGCATAGGAGAATTAATCACACTGTATGCCTCAA TGTATATGGGGGGGGGTGCATTGAATATGTGTTTTCCAGTTAGTCTTTCAAAAAAAAAAA GAAAAAAGAAAACTGGATAACTTGTTAAAATTTACTTATCTAATAGTCTTTAGTGAGTGA CTATTTTGCAGAAAAGGAGTAATGAGAGGAATATCTCATCACTATGCATGGTAATAAAAC TGTCAACTTTTAAAGTGTAACATGGTCAGCTGAGGTGTTTATTAAAAGTCAGATTCCTGG ACCCCTCTTTTCAAGATTCTGACCAGTGTGTCTGGAAGAGAGCTCAGGAATCTGCATCTG GAACAAATCCTTCAGGTGACCTCACTTGGGAAACATCTGGCTGGCGGGGTCCTTTATGTC ACAAGGCACATTCGCATGCCATCTGTCATGTATTTCTTTACCTGTCCTGTACAACTCAGA CCTTGTAGAAAAAAATCAGTTTAATAGCATGAAAAAATAACTTCCCAAGGGAGTTGCTGA AAAATACCTTATTTGTCAACACCGTGTTATGCATTCTAAGAATTAAATGCTCAGGTATTT TTACAAGATTTGACATTTAGTTAGGTCAGTTCCTGTTTTTACGTTGTGCCATTTCCCTTT TCCCCAAACATGTAGGAGCCAAGCAGCTCACCCTGGAGGACCCGCAGATGTCCATGAGCC ACCCCTACACCATGACAACGCCTTACCCTTCGCTCCCAGCCCAGGTATGGTGGAGGGCAC TGGGCTCCCTGAGGGCGAGGCTGTGTGGGCCAGCTGCCCACATGGCCAGAGAACCACAGC AGCCCAGACAGCAGAACTTGCCATTTGCTATGGCTGCTCCAACAGCCCAGAAAAACCCCA GGTCACTGAACGAATGTCTCACTTTCCACACGGTGCTGCCATTGGTGTGGATTTTAAGTT GGGGAGGGTCGGGCGTGTCCGCCTGTTGGAATATGCTTCTCAGGTCTTCTGGGAAACAGA TGTTTTGTGGAAGTGGAAGATTTTGGAAGTAGTGCCTTATCATGTGAAACCACAGGGCAG CTGATCTCTTCAGGCTTTCTTGATGTGAATGACAGCTTTGTTTCATCCACTTTGGTGGGT AAAAGAAGGCAAATTCCCCTGTGGTACTTTTGGTGCCAGGTTTAGCCATATGACGAAGCT TTACATAAAACAGTACAAGTATCTCCATTGTCCTTTATGATCCTCCATGAGTGTTTTCAC TTAGTCTGATGAAGGGTTCACTCCAGTCTTTTCGGATGATAAAATGCTTCGGCTGTCAGT CTAATAAGGGATTCCCTGAGGAGTTTGGAGGCTGTAAGAGCACCCCCCGTCTCAATGCCA GTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTGCTTCC TATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTGCTTCCTATCTCAG CCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTGCTTCTTATCTCAGCCTCTCCT GCACTCCTTTACCCCCGTCTCAATGCCAGTGCTTCCTATCTCAGCCTCTCCTGCACTCCT TTAACCCCGTCTCGATGCCAGTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCC GTCTCAATGCCAGTGCTTCCTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCAAT GCCAGTGCTTCCTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTGC TTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCGATGCCAGTGCTTCCTATC TCAGCCTCTCCTGCACTCCTTTACCCCCGTCTCAATGCCAGTGCTTCTTATCTCAGCCTC TCCTGCACTCCTTTAGCAGGTTCACAACTACATGATGCCACCCCTCGACCGAAGCTGGAG GGACTACGTCCCGGATCAGCCACACCCGGAAATCCCGTACCAATGTCCCATGACGTTTGG ACCCCGCGGCCACCACTGGCAAGGCCCAGCTTGTGAAAATGGTAAGGAGGATACCAGTGC AGGAAATAGAAGAGCTAATTGCTAATGTGGCCATGGGCCATGGCGAATCCTGGTCTGTCC TGGGCAGCACCAAAGCTCTTTCCCCTTCTTAGAGGCTGCGTGTGCAGCTCGGGGAGAGGG GGGTTTTCTCACTCCTGTGGGATGGTGGCATCCCACAGCCAAGTTTACTCTCAGGATCCA TGCTAGGCACTGCCCTTCGTGGGATCTTATTTAAACACCACAGAGATCACTCCAGGCAGT GGAAAACAGCCCCCCACTTTTTATATAGAGAGGAGATTGTGGAAGCTCATAAATAATAAG TAGGGATGCTGGGAGATTATTGAGCTGGTATATTTCTCTCGAATAGTGGTGTGTTCATTG TTGCTATTGTTGGAATTAGAGGTGATACTAAAAAAGGAACGGAAAAATACCATGGCAAAC ACATAAAACGTCTCTACAGGTGCCTACCTACCACTGGGTCCCAGAAAGACTTGCTGATTG TGGATTAGATGTGGTCCCCTGCCCTCGGGAGTTCCCCAGACATCAAAATGAGCTCCCTCA GCAGAAGCTCTCATTAGCTGGGTGCAGGGAGAATCTAGCAATGCGGTAACTCAGGCCTTC AGGACTTTTGAGTTAGTTACTTAAATGGAAGTCCTGAGACAGGTCAACACACTGAACCCT TTGGATGTTTTAGGAATATTTGTTCCTTTGCAATTTGGCCTTTTTTTCCCCAGTCATGTT CAGGTTATCCTTGGCTGCAGGTAGTGAAGAGGTGTACCACTCTTTAATGTTTGTACTGAG TGGCATGTTCACAAAAAAGCTCAGAATTCAGTTGCATTGGCTTTTCAAGAGGGATTTGCA GCAAGGGCTGGTTTCCAATATGGTAGTGGAGGAATTGGCTAACATAAAACTAGCTCCTGA AATTCAGACTTGCGTTTACTGCTCTGGCTCTATGGAATTAGTAACCATGGGAAAGAGGCA ATGCTTAGAACTGTGTAAAGTGATGGAGTAGGTAGAGACCTGTCTTGAAGCATCGGTAAC AGTAAATGAAGCAGCAGCAAGATCAGGTGTTCTGTGCCACATTCTTTTTCCATTCATGTT TCATACAACATTGTCTTCAGGAACATGGTTCAGTGTTCTCCCAACCCACAAGAGACAAGC AAAATAAAAATGGACTAAATAATTTGCTAGTTTTTAATTGGGCTCTTTGGCACAGACTCA AGTAGACCTGAACTCTCAGCTCTGTTGTGAACCCGCTTTGTGAACAAGGACAAAGCATGT CATCTGTCTCTGAGCCTCAGTCTCCCTGTTAGTCAGTTACAGAGAGAGCGCTCCAAGTTT CCTTCCAAAGCTGTGCACTGGCTCGTTTCTCCATCAGCTTTGGTTTTCCAGTTGGTCTCC AGCTCATCTTTGCCTCACAAGAGCGTGCCCTGCTAGTTGCTGGTGCTGGGAGTGGGTGGG AAGGTGATTGGGCGCCAGCCCCTTCCTTCCCAGGCTTCACACACACACCCCAGGAAGCCC CGCGGTGCGTCGGACTCTCTGTCTAGACATCATCTGATTTTTATTTGCAAATGCAGGTTG CCAGGTGACAGGAACCTTTTATGCTTGTGCCCCACCTGAGTCCCAGGCTCCCGGAGTCCC CACAGAGCCAAGCATAAGGTCTGCCGAAGCCTTGGCGTTCTCAGGTGAGTGCAGGGTTTG CTCCTGGAGGCACCGCAGGAGGCCAGCCTCTGCTGCCAGCTCTGTCATCTTTGGGCAGAT TCGATGGGACTTTAGACACTTGCTTTGCTCCCTCTGGGGTCTGGAGTAGATGTAGACACA TCCTGTGTGTGAGGTGACCAGGGTGATTTAGGAGCACCATTAGAAAACCTGACATCACTG CTTGTGGTTCTGCTGACCGTTTCAGCCACTGGCTTGAATGGAGTCATTTTGGCTTCTTCA CTGGCACCTCTCTGAATTTCTAGGAATGTGCCTTTACCTTTACCGAGGGCCCCTCTTCAG CCAACATTCTCACGATGTGGAATAATTGCTTGGAAGTGTAGAAGGGCTTCTCATTTTGAG AAGCTGATCATCCTTCCAGGTTGAGCCACAAATAAGTCCTCCTCCTCTACTCCCTGGGGA CATTAGTTCTGGTCCCTCATCTCTAAAACATTGATGTGCCTAAGAGTAATACACATTTTG GTCTTCCTCTGAACTTTAATATAGCTTGCAAACAAATATGGATTCAATCTGATTTTTAAA GTTTTATTTCTAAAAAAAAAAAAAAAATCCCTGCACCATGGAGATCTTACCTACTATAAA GAAGGCACCTCTAGGCTTGGCAAGCACACGTGCTATATGTATATTTATTTTTCAGATAAT ATTTTGGATTGTTTTTAAATGGGATTTGTTTTTATATTAAAACCAAATAGCTTAAGGTTT GGAATTCTCATCTTGCCCTCTGGCATCTTTAAAAATCAGTGATGAAAAATACTAACTAAA TTCTGAAGGTTTCAGGGAGGCGAGAGTTGTGGCACTTTTGCTGCTCAGAGGGGAGCTGGA GTTTGACCTACCAGCTCTTTCTAGTTGTGAATGAGGCTTGCACCTTTTTTTCTGAGGTGC TCGTGAGTAACTGAGGATGCCCTTTGGGAGGAGGTGCTTCTGAGCAGGAAGGCTTGTGTT TGTTTTTAGAAACTTTCAAACCCTTGTCTTGAACACCTAAGACTTGTGTGGGTGCCTGAA GAGTAGGAAATAAACAGCTATTTATATCTCGGCAACCTCGTGATTTCTGATGACATTAAA TGAAATGAAACCTGCCCCGAGAATCACCTCGAATGGCCAACACCCACTCTCTTTGGGGCG CACTGTCTGACTCGCTTTCAGACAGTGTGTTGAAGCAGAGAATTGAGACAGTGATGTGGG TTAAGTCTCAAAACCTGCTGTTGAGGAATAAGATAGTTTTGTGGGTTTCTTTTTTTGGTA TGCATGATACAGATTAATTATCAGCCATGAGCACATTTATTAGATAACTGTGATTCCCAT TGATTTTGGGGTTCCATACAGTTACCAGTGGCAGCTGCCTCCTGTCTGTGCCACTCCCCT GCGGTCTGGCTGAGGAGCTTGTGCAAACCCAGCTTGGTTCTTTCAACTCATGGGCGATAT TTTAAAGAGGCTTCTGAAATCAGCAAAACGTTTGTAAATGGATTCATCTTGTTTAAAGTT TCAGAGAGCGCAGTTTTAGAGTTCTTTTCAAACTTAAACACAAAGCCCAGTGGGAATTTC AGCAGACTTTACATGAACTTTTAGAGTATTTTTCTCATTAATTTCTTTCTTTTCACAAGA ATTAATTTTGTGATAAAAACACCACATATCCAGTGTGGAAAACTAATTTAAAAATCAGAA AAACAAAAATGGAAAATAAAAATATCACATTCTACCACCCAGAAATCACCATTAAGGCCT CAGTGCTTACCCTTTAATGTGTGTATGTGAGTGTGTTTATATATAAATTATATAGACATA AATAATTAAGCACCTAATTCTATATATAATTTATATATGTACACACACACACACACACAC ACACATTTGCTTTTTACCTAAATGATGTCATGTTATTATTTTGGGGACGTTTCAGGTATG TGGACCGACTTGCTTCTTTCTGAAACACCGTTATATTTTTTGCTAGTATAAATTAAACTT AGGGTTCATTTCCTCCAAAGTAAAAATTGATTTGCTTAAAGATGAATTTTCATTCAGTGA CACATGACTTAAATGACATCACCACTATCATCATCATAATTCACAAATAAGACTTAGCAA GTTCTTAATAGTGATGCTCTATAATAGGAATTCAACTTACATTTCCAGAAAATTAATGAA AGATACACTTGTTCCTTAAAAAAAGAGTCGGTGGCCACATACGTTTGTAATATGCTGGTT TAGACAGATTAAATGGGTTTCTTTCCACGGGACTTCTCCAAGTGTTGACCGAGCTCATGC TGTCTGTGGATCTCTGGGGGAGACAAGGGCACGCTGTGTTTCCCAGGCCTCCTTGACGCG GGAACCTTTTGTTCCCCCACGGGACATGTGGGACACTAGAGTTCCACCACAGGTGCTTGG CTCTGTGGAGTCGTTGGCCTCGAGGTGGTGTCCTTGGCCCCCAGCACTGACTCCGGAGCT CTGTGTTTGCAGACTGCCGGCTGCACATCTGCCTGTACTACCGGGAAATCCTCGTGAAGG AGCTGACCACGTCCAGCCCCGAGGGCTGCCGGATCTCCCATGGACATACGTATGACGCCA GCAACCTGGACCAGGTCCTGTTCCCCTACCCAGAGGACAATGGCCAGAGGAAAAACATTG AGAAGCTGCTGAGCCACCTGGAGAGGGGCGTGGTCCTCTGGATGGCCCCCGACGGGCTCT ATGCGAAAAGACTGTGCCAGAGCAGGATCTACTGGGACGGGCCCCTGGCGCTGTGCAACG ACCGGCCCAACAAACTGGAGAGAGACCAGACCTGCAAGCTCTTTGACACACAGCAGTTCT TGTCAGGTAAGGCACCTCGTTATCTGTTAGAATGGAGGTGGTGATGGCCTGCCTGCCACA GGGGTCAGAAACCACAGGGTCCCTCCCACCCCAGGCTGAGGTCTTCCTCCTGTTGACTTC GGCGCCCACTGGGCTTGGGGCTTGACTCCAGTAGAGATCTTCTGTCTGGCTCTGTTGTGG GCAGAGAGTCCGGATCAGATGGTCCAGGTGGACCATGGCTCAGGCTGTTCTCTTGCAATT CTGGTTTTCAGCAGTCGCCTCTTAAAACAGTTCCATTTCATTGCACTATGATCTCGACAA ATACGTCTGCTGATGTGGCGGCTCTTTTCAGGTTCCCAGAAAAATCATAAAGGTTGGAAG CATATTGTTAACATTCTTGGTTGTCAGGTGTGTCACCCTCATGCAGATGCTGGCCCACGA GTGAGACGGAGGGTGGAGTGGACTGTACTGGTTTTGCACAGGAGAAGTTATAGGAGAGTG CTATAAGTTGGCTCTGTGATATGAACATTTCTAAGCATATTTTTCAGAACCAGTGAGTTT TGTTTTTCTACCTTGGATTTCATGACAATTCAGCGAACCTCTGGCTGGCTTCTGTGAAGC CCCTCGCCCTGTCATGCTGGGCTTCCTCACTGGCTTTGTGGGGCTGTCCAGGTGGAGGGA GCCTCCCGCGTGGGAGGGAGCTGCTCTACCCGCCACTCGCCACCCCACCGCCAACTCTTC CTCTGCCTTTTCCCAGTCCTGTCCCTTCCTGAGCCCCTTCAGAAACTCCTGTGTCTTTGA TTTCTCATGTGCCTCCCCTTTTCTTGAATGTGCTTCTTCATTCAACTTATTTAAAATAAA AATATGACACGTCTGTGTGCTCTGGCACTGTTGACATGTGCTCGTACTTCTGGGTGTAAG TGACCCAAGTTTTTGTAAGCTCATCCAGATTTTCTTTTGGTGCCCAAAGCAAATATGTCC CCAGATAACTAAGCTTCAGGCCAGGTGTGGTGGCCCATGCCTGTAATCCCAGCACTTTAG GAGGCTGAGGTGGGCAGATCACTTGAGGCCAGGAGTTCAAGACCAGCCTGGCCAACATGG CAAAACCCCGTCTCTACTAAAGATACAAAAATTAGCTGGGCGTGATGGTGGGCGCCTGTA ATCCCAGCTACTCAGGAGGATGAGGCACAAGAATCGCTTGAACCTGTGGGAGGCGGAGGT TGCAGTGAGCTGAGATCGCACCACGGTGCTGCAGTTTGCAGGACAGAGCGAGACTCCATT GCCCCCCGCACCACAAAAAAATAACTAAGCTCACACAGAGGCTGACCATAGGAAGAGGGA GAACTGTGCTGGTTCCCCGAGGCGGCGGCAAGTGAGGAAGTCACCTGGGGCTGGACACCT CTCATTCTAAGGGCAGAACCATCCCCAAGCCCTGGCCAGGGCGGTCCCATCCTTCTTGGG GTTGGGCATGGTGTTCATGGGGGACCAAGGAAATTGAAGGGCAACTGGGGGGACCCCCCC TCCCCTGTCAGCATCTCCTGTGTCTGCCTTGGGATCTGGAAGAGCTCACATGGGCCAGGA AGGCTAAGGCCCACTGGGCCTGGATTTCTGAAGACTCTGGACCTTGGTGCCAGTGGATTC AGAAGATACCACAAGGTGAGGGCTTTCTAATGAAAGTGTCACAAGGAACTGGCACTGGCT TTTCTGAGTGCCTCTTGCTGGGCGTTTTTAGGGAGGTAGAGCCCCCGTGGTGACTAAGCT GGAAGGTGCACATTGAGTCACAGGTGCACTGCGTGAGAGACAGCACAGGCAGGGGGTGGA CGCCTGTGAGTGTCCTGGGGCTGTAGACTTGCGCGACTAGAACTTACTATTAATCTGTGA GCAAGAGCTGGTCTTGGCTTTCATTCCTTCCTCTGTAACCAAGGGCTGTGCTCTTTGCCC ACTGCAGCCTCTCACCTCAAAGTGTTCACTGAGGTTCAAGGAGGATGCTGTGAACGTAAA AACTGCAGCTGTGCCAACCAGCTTCTGCATAATTAAGGATTCCCACCAAACACTCTCATG TTATCTAGGGTTGGAGCCATGCTTTCTCAGAGAATTGTGCCAACTCGCCATTCTGATTAG CCTGTGTAGGTGTAGTCTCAGATCACGGCAGTGTGAATGTATTTTACAGATTCTGACTAA GTCATTTGGGTTTGATTTGAATTCTGGAAAAAAAAAAAAGCAGGAAGTCAAATAGTCCTG TAAGTTAGCTAGAAACTTCTGTTCAGTTGAAGAGAACAGTGGAGATCTTTGATATCTTCC TATTCAGGTCTGCACAGCACTAGGGACAGCCCCCAGGGCCCGGCCCGAGGGTGTGTATCT GATAAGGACGCGTCTGTTCTGCAGAAGCTGTAGCGGCTCCTGTGTCAACTCGTTTCTTTT GCGGGCGTGACATTTTATTGTAGCTACAGGCAGAAGATTTGTCTTGTGTACAGGGGAGGG AGCATGGGCTAAAGTCAGGGGATGGGCACTTGTCTTTCCAACAATGTTCCAGTCCGTTTT GTATCTTTTGGGTAGGTGTGGTGGCTTCAGGATGTACATGTGTATATCCACAAGCGGGAG GCCAGGGGGGCTGCCCCACTCCTGTTCTCAAGTCAAGTTACTGTTCCATCCCTGGAGACA GGCAAGAAGTCTACTCAGAGTTACACAGTTCAGGCATAGTGACAGTGGGACTCAGCTGCC GATGGCTGGTGCTCAGTCACCACGTTGACGTTACATATTTTCTGTGGTGCCTGAGTTACG TGGATGTCCGCAGTAGCACAGATACTGGATTATGTGGGCTCTGTAGTGAGGGGATGAGGT TTTAAAATGATCCTGGGATGTCGAAACATTCTGATTTTTTAAATGAAAACTTGTCCATGG CATAAATTGGTCTTTTGCCATTGCGTGACTACGTTTCTTGTTCTTTATCTCCCGACTTCA CTGTGGTCTACTACCTTTTGAATCTTCGTGGGTCCAATGCTGCAAAGCAGTGTTCTTTAG CTGTCGACTAGTTCCTCTTGAAGAATCGAGGGAGACCGAGGGCCCTGGGGGGAAAGCACC CAAAGGAATGCATACATGCTATTTTGTATCTGAGATGTTCACATCAAGAGCCCCACTCAG CGGAGTAAGAGTGCTCATTCCTCTTGCAGTGTTCAGAATCACAGTAAGCTCTTGCTTCCT GTTTAACCTGGTGTGTTCGGTGATGAGGGTTTCTGAACATGGTCTCTTTCTTGTGGGCTT CTACAGAGCTGCAAGCGTTTGCTCACCACGGCCGCTCCCTGCCAAGATTCCAGGTGACTC TATGCTTTGGAGAGGAGTTTCCAGACCCTCAGAGGCAAAGAAAGCTCATCACAGCTCACG TGAGTCCTCAGTTACACTCCTACCATAGTGGCTTCCTGTTCTTTGTAAAGGCCAGAGTTT CATTTAGAAAAGTCCCAAATGAAAAGTAAATGTCAAATGACCTGGAAAAATAAGCGTAAC CCTTAAACTAGTGAGGGAGGAAGCATGGTCCAACGAGCAGCACAGTCTGAGGACTCACGT GCTCCTCCCAGACTTGAGATCTGCTCATCAAAGAACCAGGGAGGACAGCCTCAAAGGAGG GTGCCTCTTTCCCCATCTTTTTTATTTTTCAGGAAAGTTGTCGTATTTCCATTTTATAGG GATTGAAAAAGATTGATGGTTAAAGTTGCCCTTTAAAATTCTCCAGGTTAAGATTGCTGT AAGAATGCTATCTAGCTAGTGGATCTTCATTCAATGGAAAAGCTTTTCCCAAATGAGAAA CTATCCATTCCCTGGAGGCATTTTGTAGGTCTCTGCAGCTGTGTCCTAGCACCTCTTTTA TTTCTGGAATTTTAGAAATTATTTAATTATTGGGCATATGATATTTGAAAGAGGCTGAAT CTTTCAAGGAATTCAAGCAAATCAGACCCTCTCGTAATGTTCTCTAGCATAGCTCAAGAT GGGTTCAACTGTGGCAAGTAACACTAAAAGGGTAGGGTTAGGATTAGGGTTAGAGTTTTC TTTTTTATGAGAAAAGGTTTCCATAGATAACATGAAGCATTAATTTGCCATGGGAAACAG AATCTTGAACCCTTAAGACTTTTGAATTTGAAAACTTCACATTGCTACATACTTGCAAGC ATTATTAACGGGCTTGCATGCTGAGCAATACCAGGTAAAAGTTACACCCCCTAACATCAA AGTTCTCATCATGTTCTAGCTCTGATGCTATTTCTCATTGAGAACTGAAATGAAACATGG TTTAATCTTGAACATACAACCCCCCTTCTTGATTTTAAAAACAAAGACCAGCCAACCAAC CAGTATATAATCCCATAGACTCAGGAGTTTTCTCATGAGTTCTCTCCAGTGATTGACTTA ATAATTGATATGATTGTTGAAATAATAACTGATACATTGTTAACAACAGGAATTGCTAAA TGACTAAATAAACTTGGCATTGATAAGCAGCATTTAAGAAGTTGATGATCGGCCGGGCAC AGTGGCTCACGCCTGTAATCCCGGCACTTTGGGAGGCTGAGGCGGGCAGATCATGTGGTC AGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCCTCTCTACTAAAAATACAAAA ATTAGCCGGGCGTGGTGGTGCGCACCTGTAATCCCAGCTACTCGGGAGGCTGAAGCAAGG GAGTCACTTGAACCCAGGAGTCAGAGCTTGCAGTGAGCCGAGATTGCACCACTGCACTCC AGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAAAAAAACAAAAAAAGAAGTTGATGAT CAGCTCAGCTATCACATCAATCCAGTTTTAAAGTTGACATGGATGCAAGTCACTGTCCTC TAAGTCAGGGAAAGATGGATCCCCAGATGACCCCCTCATGCTGAAGACGAGGCTGCGTGG TCCATAAAATGAATAAACACACGTGTACACCTATGAGTTCCACTTTTAAAAATTATTAAT TTAATTCATTTCAGGTACTTAGGAGTTTAGCTTAAGTCGTCATATATAAAATACAGTCTC TAATATCATGATTGATGGAGAGCATTCAGCTTGCCTTAGATGCTGTAAATTCAGGAAAAG CTGAACATTAAGGCGTTTTTGTTTTTTGGTGAGTGTGATCCACGCTAATAACCAGACAGT ATAAATTTGAGGCCAGTTAGCTTCTCTTTTTCCACAATAGTAGTTTTGTTGTTGTTTAAC TTTACTTTTTATTTCTTTTACCTCTGGTTGAGAACTATACAGATTACCTAGAAATCAAAT CATTCAGGATGAGCTCCTTGTTTCTTTCAAACTGCAGTTGTGGAAAAACAAAATCATTGG CCTAAATTACCCTGCAGATTCCCTCAGACTTCCTTTTAATTTGATCACTTTACTTGATTT GATGCAGTTTTAGTTAAATGTACATTTTAAGTGGCAGTCGATTTGAAAGTAACATCTTTA ACCCAGAATTAAGTCACTTTGGCTGTTTTTTTACATGTTGATCTATGGAAGGACTAACCA AAAAATTGCTTCTTTAGATGGCTCCAAATATGAAATGTTTTGATGTGTTCTAGGATGTAA CTTTGGGCTTTACGTTACTGTCTCCTTAGAATCTGAGTGCTGTTTAATAGTGAGCCAGTT GCAGGATATCTCAGTAATGTCTTTTTAAAATCTCTTATTAAAGGTAGAACCTCTGCTAGC CAGACAACTATATTATTTTGCTCAACAAAACAGTGGACATTTCCTGAGGGGCTACGATTT ACCAGAACACATCAGCAATCCAGAAGATTACCACAGATCTATCCGCCATTCCTCTATTCA AGAATGAAAAATGTCAAGATGAGTGGTTTTCTTTTTCCTTTTTTTTTTTTTTTTTTTGAT ACGGGGATACGGGGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAGTGACACAATCTCAGCT CACTGTGACCTCCGCCTCCTGGGTTCAAGAGACTCTCCTGCCTCAGCCTCCCTGGTAGCT GGGATTACAGGTGTGAGCCACTGCACCCACCCAAGACAAGTGATTTTCATTGTAAATATT TGACTTTAGTGAAAGCGTCCAATTGACTGCCCTCTTACTGTTTTGAGGAATTCAGAAGTG GAGATTTCAGTTCAGCGGTTGAGGAGAATTGCGGCGAGACAAGCATGGAAAATCAGTGAC ATCTGATTGGCAGATGAGCTTATTTCAAAAGGAAGGGTGGCTTTGCATTTCTTGTGTTCT GTAGACTGCCATCATTGATGATCACTGTGAAAATTGACCAAGTGATGTGTTTACATTTAC TGAAATGCGCTCTTTAATTTGTTGTAGATTAGGTCTTGCTGGAAGACAGAGAAAACTTGC CTTTCAGTATTGACACTGACTAGAGTGATGACTGCTTGTAGGTATGTCTGTGCCATTTCT CAGGGAAGTAAGATGTAAATTGAAGAAGCCTCACACGTAAAAGAAATGTATTAATGTATG TAGGAGCTGCAGTTCTTGTGGAAGACACTTGCTGAGTGAAGGAAATGAATCTTTGACTGA AGCCGTGCCTGTAGCCTTGGGGAGGCCCATCCCCCACCTGCCAGCGGTTTCCTGGTGTGG GTCCCTCTGCCCCGCCCTCCTTCCCATTGGCTTTCTCTCCTTGGCCTTTCCTGGAAGCCA GTTAGTAAACTTCCTATTTTCTTGAGTCAAAAAACATGAGCGCTACTCTTGGATGGGACA TTTTTGTCTGTCCTACAATCTAGTAATGTCTAAGTAATGGTTAAGTTTTCTTGTTTCTGC ATCTTTTTGACCCTCATTCTTTAGAGATGCTAAAATTCTTCGCATAAAGAAGAAGAAATT AAGGAACATAAATCTTAATACTTGAACTGTTGCCCTTCTGTCCAAGTACTTAACTATCTG TTCCCTTCCTCTGTGCCACGCTCCTCTGTTTGTTTGGCTGTCCAGCGATCAGCCATGGCG ACACTAAAGGAGGAGGAGCCGGGGACTCCCAGGCTGGAGAGCACTGCCAGGACCCACCAC TGGAAGCAGGATGGAGCTGACTACGGAACTGCACACTCAGTGGGCTGTTTCTGCTTATTT CATCTGTTCTATGCTTCCTCGTGCCAATTATAGTTTGACAGGGCCTTAAAATTACTTGGC TTTTTCCAAATGCTTCTATTTATAGAATCCCAAAGACCTCCACTTGCTTAAGTATACCTA TCACTTACATTTTTGTGGTTTTGAGAAAGTACAGCAGTAGACTGGGGCGTCACCTCCAGG CCGTTTCTCATACTACAGGATATTTACTATTACTCCCAGGATCAGCAGAAGATTGCGTAG CTCTCAAATGTGTGTTCCTGCTTTTCTAATGGATATTTTAAATTCATTCAACAAGCACCT AGTAAGTGCCTGCTGTATCCCTACATTACACAGTTCAGCCTTTATCAAGCTTAGTGAGCA GTGAGCACTGAAACATTATTTTTTAATGTTTAAAAAGTTTCTAATATTAAAGTCAGAATA TTAATACAATTAATATTAATATTAACTACAGAAAAGACAAACAGTAGAGAACAGCAAAAA AATAAAAAGGATCTCCTTTTTTCCCAGCCCAAATTCTCCTCTCTAAAAGTGTCCACAAGA AGGGGTGTTTATTCTTCCAACACATTTCACTTTTCTGTAAATATACATAAACTTAAAAAG AAAACCTCATGGAGTCATCTTGCACACACTTTCATGCAGTGCTCTTTGTAGCTAACAGTG AAGATTTACCTCGTTCTGCTCAGAGGCCTTGCTGTGGAGCTCCACTGCCATGTACCCAGT AGGGTTTGACATTTCATTAGCCATGCAACATGGATATGTATTGGGCAGCAGACTGTGTTT CGTGAACTGCAGTGATGTATACATCTTATAGATGCAAAGTATTTTGGGGTATATTATCCT AAGGGAAGATAAAGATGATATTAAGAACTGCTGTTTCACGGGGCCCTTACCTGTGACCCT CTTTGCTGAAGAATATTTAACCCCACACAGCACTTCAAAGAAGCTGTCTTGGAAGTCTGT CTCAGGAGCACCCTGTCTTCTTAATTCTCCAAGCGGATGCTCCATTTCAATTGCTTTGTG ACTTCTTCTTCTTTGTTTTTTTAAATATTATGCTGCTTTAACAGTGGAGCTGAATTTTCT GGAAAATGCTTCTTGGCTGGGGCCACTACCTCCTTTCCTATCTTTACATCTATGTGTATG TTGACTTTTTAAAATTCTGAGTGATCCAGGGTATGACCTAGGGAATGAACTAGCTATGAA ATACTCAGGGTTAGGAATCCTAGCACTTGTCTCAGGACTCTGAAAAGGAACGGCTTCCTC ATTCCTTGTCTTGATAAAGTGGAATTGGCAAACTAGAATTTAGTTTGTACTCAGTGGACA GTGCTGTTGAAGATTTGAGGACTTGTTAAAGAGCACTGGGTCATATGGAAAAAATGTATG TGTCTCCCAGGTGCATTTCTTGGTTTATGTCTTGTTCTTGAGATTTTGTATATTTAGGAA AACCTCAAGCAGTAATTAATATCTCCTGGAACACTATAGAGAACCAAGTGACCGACTCAT TTACAACTGAAACCTAGGAAGCCCCTGAGTCCTGAGCGAAAACAGGAGAGTTAGTCGCCC TACAGAAAACCCAGCTAGACTATTGGGTATGAACTAAAAAGAGACTGTGCCATGGTGAGA AAAATGTAAAATCCTACAGTGAAATGAGCAGCCCTTACAGTATTGTTACCACCAAGGGCA GGTAGGTATTAGTGTTTGAAAAAGCTGGTCTTTGAGCGAGGGCATAAATACAGCTAGCCC CAGGGGTGGAACAACTCTGGGAGTCTTGGGTACTCGCACCTCTTGGCTTTGTTGATGCTC CGCCAGGAAGGCCACTTGTGTGTGCGTGTCAGTTACTTTTTTAGTAACAATTCAGATCCA GTGTAAACTTCCGTTCATTGCTCTCCAGTCACATGCCCCCACTTCCCCACAGGTGAAAGT TTTTCTGAAAGTGTTGGGATTGGTTAAGGTCTTTATTTGTATTACGTATCTCCCGAAGTC CTCTGTGGCCAGCTGCATCTGTCTGAATGGTGCGTGAAGGCTCTCAGACCTTACACACCA TTTTGTAAGTTATGTTTTACATGCCCCGTTTTTGAGACTGATCTCGATGCAGGTGGATCT CCTTGAGATCCTGATAGCCTGTTACAGGAATGAAGTAAAGGTCAGTTTTTTTTTGTATTG ATTTTCACAGCTTTGAGGAACATGCATAAGAAATGTAGCTGAAGTAGAGGGGACGTGAGA GAAGGGCCAGGCCGGCAGGCCAACCCTCCTCCAATGGAAATTCCCGTGTTGCTTCAAACT GAGACAGATGGGACTTAACAGGCAATGGGGTCCACTTCCCCCTCTTCAGCATCCCCCGTA CCCCACTTTCTGCTGAAAGAACTGCCAGCAGGTAGGACCCCAGAGGCCCCCAAATGAAAG CTTGAATTTCCCCTACTGGCTCTGCGTTTTGCTGAGATCTGTAGGAAAGGATGCTTCACA AACTGAGGTAGATAATGCTATGCTGTCGTTGGTATACATCATGAATTTTTATGTAAATTG CTCTGCAAAGCAAATTGATATGTTTGATAAATTTATGTTTTTAGGTAAATAAAAACTTTT AAAAATTTGTTA OMIM ID 601900