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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IRF4 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006351 transcription, DNA-dependent NAS GO:0006355 regulation of transcription, DNA-dependent NAS GO:0019221 cytokine-mediated signaling pathway TAS GO:0042110 T cell activation NAS GO:0043011 myeloid dendritic cell differentiation IEA GO:0043388 positive regulation of DNA binding IEA GO:0043966 histone H3 acetylation IEA GO:0043967 histone H4 acetylation IEA GO:0045082 positive regulation of interleukin-10 biosynthetic process IDA GO:0045086 positive regulation of interleukin-2 biosynthetic process IDA GO:0045368 positive regulation of interleukin-13 biosynthetic process IDA GO:0045404 positive regulation of interleukin-4 biosynthetic process IDA GO:0045622 regulation of T-helper cell differentiation NAS GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0060333 interferon-gamma-mediated signaling pathway TAS GO:0060337 type I interferon-mediated signaling pathway TAS cellular_component GO:0000788 nuclear nucleosome IEA GO:0005634 nucleus IC GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS molecular_function GO:0000975 regulatory region DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003700 sequence-specific DNA binding transcription factor activity NAS GO:0008134 transcription factor binding NAS

Protein-protein interaction details for IRF4 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRAF2 Two-hybrid physical 16189514 STAT6 Reconstituted Complex physical 10601358 STAT6 Affinity Capture-Western physical 10601358 BCL6 Affinity Capture-Western physical 10601358 BCL6 Reconstituted Complex physical 10601358 BCL6 Affinity Capture-Western physical 10601358 FKBP4 Affinity Capture-Western physical 10714679 NFATC2 Affinity Capture-Western physical 11956291 NFATC2 Affinity Capture-Western physical 11956291 SPI1 Reconstituted Complex physical 10022840 SPI1 Co-crystal Structure physical 12372320 HOXC11 Two-hybrid physical 20211142 PROX1 Two-hybrid physical 20211142 HOXB13 Two-hybrid physical 20211142 BATF Two-hybrid physical 20211142 ETV7 Two-hybrid physical 20211142 BAT2L1 Affinity Capture-MS physical 21903422 CARM1 Affinity Capture-MS physical 21903422 IKBKAP Affinity Capture-MS physical 21903422 IRAK1 Affinity Capture-MS physical 21903422 PEG10 Affinity Capture-MS physical 21903422 TLK2 Affinity Capture-MS physical 21903422 VPS35 Affinity Capture-MS physical 21903422 YTHDC2 Affinity Capture-MS physical 21903422 IKBKAP Reconstituted Complex physical 21903422 IRAK1 Reconstituted Complex physical 21903422 TLK2 Reconstituted Complex physical 21903422 YTHDC2 Reconstituted Complex physical 21903422