Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for JAK3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3718
Official gene symbolJAK3
Full nameJanus kinase 3
Aliases,JAK-3,JAK3_HUMAN,JAKL,L-JAK,LJAK,
Gene summaryThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.1
Gene position17958841 - 17935591  Map Viewer
Gene orientationminus
Gene size23251 bp
Gene sequence
OMIM ID600173