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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for JUP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3728
Official gene symbolJUP
Full namejunction plakoglobin
Aliases,ARVD12,CTNNG,DP3,DPIII,PDGB,PKGB,
Gene summaryThis gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21
Gene position39942964 - 39910859  Map Viewer
Gene orientationminus
Gene size32106 bp
Gene sequence
OMIM ID173325