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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for JUP (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0000902 cell morphogenesis IBA GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway IBA GO:0003181 atrioventricular valve morphogenesis IBA GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development IBA GO:0007016 cytoskeletal anchoring at plasma membrane IBA GO:0007369 gastrulation IBA GO:0007398 ectoderm development IBA GO:0007399 nervous system development IBA GO:0016331 morphogenesis of embryonic epithelium IBA GO:0016337 cell-cell adhesion IDA GO:0016337 cell-cell adhesion IEA GO:0016477 cell migration IMP GO:0034329 cell junction assembly TAS GO:0034332 adherens junction organization TAS GO:0042307 positive regulation of protein import into nucleus IDA GO:0043588 skin development IBA GO:0045216 cell-cell junction organization TAS GO:0048599 oocyte development IBA GO:0050982 detection of mechanical stimulus IDA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0071603 endothelial cell-cell adhesion ISS GO:0071681 cellular response to indole-3-methanol IDA GO:0090263 positive regulation of canonical Wnt receptor signaling pathway IC cellular_component GO:0005634 nucleus IMP GO:0005667 transcription factor complex ISS GO:0005737 cytoplasm IEA GO:0005737 cytoplasm IMP GO:0005829 cytosol ISS GO:0005856 cytoskeleton ISS GO:0005882 intermediate filament IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005911 cell-cell junction IDA GO:0005913 cell-cell adherens junction IDA GO:0005915 zonula adherens IBA GO:0005915 zonula adherens ISS GO:0005916 fascia adherens IBA GO:0005916 fascia adherens IEA GO:0009898 internal side of plasma membrane IBA GO:0009898 internal side of plasma membrane IEA GO:0009898 internal side of plasma membrane ISS GO:0015629 actin cytoskeleton IBA GO:0015629 actin cytoskeleton IEA GO:0016323 basolateral plasma membrane IBA GO:0016327 apicolateral plasma membrane IEA GO:0016328 lateral plasma membrane IEA GO:0016342 catenin complex IDA GO:0030018 Z disc IBA GO:0030056 hemidesmosome ISS GO:0030057 desmosome IDA GO:0030057 desmosome IEA GO:0032993 protein-DNA complex IDA GO:0034747 Axin-APC-beta-catenin-GSK3B complex IBA GO:0071665 gamma-catenin-TCF7L2 complex IDA molecular_function GO:0003713 transcription coactivator activity IDA GO:0005198 structural molecule activity IBA GO:0005198 structural molecule activity IEA GO:0005199 structural constituent of cell wall IC GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0019901 protein kinase binding IBA GO:0019901 protein kinase binding IEA GO:0019903 protein phosphatase binding IPI GO:0042153 RPTP-like protein binding IBA GO:0042803 protein homodimerization activity ISS GO:0045294 alpha-catenin binding IPI GO:0045296 cadherin binding IPI

Protein-protein interaction details for JUP (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BIRC2 Two-hybrid physical 16189514 WDYHV1 Two-hybrid physical 16189514 RIBC2 Two-hybrid physical 16189514 NFKBIE Two-hybrid physical 16189514 CTNNBIP1 Two-hybrid physical 16189514 CTNNBIP1 Affinity Capture-MS physical 17353931 PHB2 Affinity Capture-MS physical 17353931 LGALS9 Affinity Capture-MS physical 17353931 CTNNB1 Affinity Capture-Western physical 9535896 CDH1 Affinity Capture-Western physical 7542250 CTNNA1 Affinity Capture-Western physical 9762469 CTNNA1 Affinity Capture-Western physical 9762469 EGFR Reconstituted Complex physical 9535896 CDH1 Affinity Capture-Western physical 9535896 MUC1 Affinity Capture-Western physical 12939402 MUC1 Co-localization physical 12939402 APC Reconstituted Complex physical 8074697 CDH1 Reconstituted Complex physical 8074697 CTNNB1 Affinity Capture-Western physical 11712088 APC Affinity Capture-Western physical 7651399 CDH3 Affinity Capture-Western physical 10910767 CDH3 Co-purification physical 10910767 CDH5 Affinity Capture-Western physical 9434630 CDH2 Affinity Capture-MS physical 14625392 PTPN14 Affinity Capture-MS physical 12808048 PKP3 Two-hybrid physical 12707304 RAB8B Affinity Capture-Western physical 12639940 ARHGDIA Two-hybrid physical 16169070 DSG3 Affinity Capture-Western physical 7738346 CDH1 Affinity Capture-Western physical 8207061 PKP2 Affinity Capture-Western physical 11790773 PKP2 Two-hybrid physical 11790773 DSG2 Affinity Capture-Western physical 11710948 ERBB2 Far Western physical 7702605 CTNNA1 Affinity Capture-Western physical 7650039 CDH2 Affinity Capture-Western physical 7650039 BTRC Affinity Capture-Western physical 10803460 DSC2 Affinity Capture-Western physical 9443898 GJB1 Affinity Capture-Western physical 7971964 DSC3 Affinity Capture-Western physical 10769211 PECAM1 Affinity Capture-Western physical 10801826 TCF7L2 Reconstituted Complex physical 11711551 DSP Affinity Capture-Western physical 9739078 CDH1 Affinity Capture-Western physical 1639850 DSG1 Reconstituted Complex physical 9606214 DSP Affinity Capture-Western physical 9348293 DSP Two-hybrid physical 9348293 DSG2 Affinity Capture-Western physical 10769205 DSG2 Reconstituted Complex physical 8749329 CTNNA1 Reconstituted Complex physical 9110993 CDH5 Affinity Capture-Western physical 12003790 PTPRF Reconstituted Complex physical 9245795 PTPRK Reconstituted Complex physical 8663237 PTPRK Affinity Capture-Western physical 8663237 USP1 Affinity Capture-MS physical 19615732 APC Two-hybrid physical 20936779 CTNNA1 Two-hybrid physical 20936779 DSC1 Two-hybrid physical 14673151 UBC Affinity Capture-MS physical 16335966 INSIG2 Affinity Capture-MS physical 19815544 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572