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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LCK (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3932
Official gene symbolLCK
Full namelymphocyte-specific protein tyrosine kinase
Aliases,LSK,YT16,p56lck,pp58lck,
Gene summaryThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p34.3
Gene position32716840 - 32751766  Map Viewer
Gene orientationplus
Gene size34927 bp
Gene sequence
OMIM ID153390