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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LRP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4035
Official gene symbolLRP1
Full namelow density lipoprotein receptor-related protein 1
Aliases,A2MR,APOER,APR,CD91,FLJ16451,IGFBP3R,LRP,MGC88725,TGFBR5,
Gene summaryThe protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q13-q14
Gene position57522282 - 57607142  Map Viewer
Gene orientationplus
Gene size84861 bp
Gene sequence
OMIM ID107770