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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for LRP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006898 receptor-mediated endocytosis IEA GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway IEA GO:0007275 multicellular organismal development IEA GO:0007568 aging IEA GO:0008283 cell proliferation IEA GO:0010875 positive regulation of cholesterol efflux ISS GO:0014912 negative regulation of smooth muscle cell migration ISS GO:0030178 negative regulation of Wnt receptor signaling pathway ISS GO:0032370 positive regulation of lipid transport ISS GO:0032374 regulation of cholesterol transport ISS GO:0032429 regulation of phospholipase A2 activity ISS GO:0032956 regulation of actin cytoskeleton organization ISS GO:0035909 aorta morphogenesis ISS GO:0042157 lipoprotein metabolic process IEA GO:0042953 lipoprotein transport NAS GO:0043277 apoptotic cell clearance ISS GO:0045768 positive regulation of anti-apoptosis IEA GO:0051222 positive regulation of protein transport IEA GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway ISS cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005768 endosome IEA GO:0005886 plasma membrane IEA GO:0005887 integral to plasma membrane ISS GO:0005905 coated pit IEA GO:0030136 clathrin-coated vesicle IEA GO:0030425 dendrite IEA GO:0043025 neuronal cell body IEA GO:0048471 perinuclear region of cytoplasm IEA molecular_function GO:0002020 protease binding IEA GO:0004872 receptor activity IEA GO:0005509 calcium ion binding IEA GO:0005509 calcium ion binding ISS GO:0005515 protein binding IPI GO:0032403 protein complex binding IDA GO:0034185 apolipoprotein binding IPI GO:0034187 apolipoprotein E binding IDA GO:0042954 lipoprotein transporter activity NAS GO:0070325 lipoprotein particle receptor binding IC

Protein-protein interaction details for LRP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SERPINE1 Affinity Capture-Western physical 15001579 CANX Affinity Capture-Western physical 14980518 CALR Affinity Capture-Western physical 14980518 PDIA2 Affinity Capture-Western physical 14980518 MMP14 Affinity Capture-Western physical 14645246 KAT5 FRET physical 12888553 CALCR Reconstituted Complex physical 12821648 CALCR Affinity Capture-Western physical 12821648 SHC1 Affinity Capture-Western physical 12789267 SHC1 Reconstituted Complex physical 12789267 THBS1 Reconstituted Complex physical 14991768 GIPC1 Two-hybrid physical 10827173 MAPK8IP1 Two-hybrid physical 10827173 DLG4 Two-hybrid physical 10827173 MAPK8IP2 Two-hybrid physical 10827173 SYNJ2BP Two-hybrid physical 10827173 NOS1AP Two-hybrid physical 10827173 SCN3A Two-hybrid physical 10827173 APBA2 Two-hybrid physical 10827173 DAB1 Two-hybrid physical 10827173 ITGB1BP1 Two-hybrid physical 10827173 ANAPC10 Two-hybrid physical 10827173 DLG4 Reconstituted Complex physical 10827173 GIPC1 Reconstituted Complex physical 10827173 MAPK8IP1 Reconstituted Complex physical 10827173 MAPK8IP2 Reconstituted Complex physical 10827173 SYNJ2BP Reconstituted Complex physical 10827173 NOS1AP Reconstituted Complex physical 10827173 ITGB1BP1 Reconstituted Complex physical 10827173 DAB1 Reconstituted Complex physical 10827173 A2M Co-crystal Structure physical 10652313 PDGFB Reconstituted Complex physical 11854294 SRC Biochemical Activity physical 11854294 SHC1 Affinity Capture-Western physical 11854294 DAB2 Reconstituted Complex physical 11247302 MDK Affinity Capture-MS physical 10772929 F8 Reconstituted Complex physical 12522143 GULP1 Reconstituted Complex physical 11729193 PLAUR Affinity Capture-Western physical 11359936 PLAUR Reconstituted Complex physical 11359936 PLAT Reconstituted Complex physical 10632583 F9 Reconstituted Complex physical 12522212 LRPAP1 Reconstituted Complex physical 1374383 LPL Reconstituted Complex physical 7510694 LPL Reconstituted Complex physical 7989348 LPL Reconstituted Complex physical 1281473 LIPC Reconstituted Complex physical 7721852 PLAT Reconstituted Complex physical 1502153 SNX17 Reconstituted Complex physical 12169628 THBS1 Reconstituted Complex physical 9045712 APBB1 Two-hybrid physical 9837937 DAB1 Two-hybrid physical 9837937 DAB1 Reconstituted Complex physical 9837937 APBB1 Reconstituted Complex physical 9837937 THBS1 Reconstituted Complex physical 7775583 USP3 Affinity Capture-MS physical 19615732 CACNA1A Two-hybrid physical 21078624