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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCL1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4170 Official gene symbol MCL1 Full name myeloid cell leukemia sequence 1 (BCL2-related) Aliases ,BCL2L3,EAT,MCL1L,MCL1S,MGC104264,MGC1839,Mcl-1,TM, Gene summary This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq] Location Chromosome: 1   Locus: 1q21 Gene position 150552136 - 150547034  Map Viewer Gene orientation minus Gene size 5103 bp Gene sequence >MCL1:complement(2035676..2040778):Length=5103 CACCCCGTAGGACTGGCCGCCCTAAAACCGTGATAAAGGAGCTGCTCGCCACTTCTCACT TCCGCTTCCTTCCAGTAAGGAGTCGGGGTCTTCCCCAGTTTTCTCAGCCAGGCGGCGGCG GCGACTGGCAATGTTTGGCCTCAAAAGAAACGCGGTAATCGGACTCAACCTCTACTGTGG GGGGGCCGGCTTGGGGGCCGGCAGCGGCGGCGCCACCCGCCCGGGAGGGCGACTTTTGGC TACGGAGAAGGAGGCCTCGGCCCGGCGAGAGATAGGGGGAGGGGAGGCCGGCGCGGTGAT TGGCGGAAGCGCCGGCGCAAGCCCCCCGTCCACCCTCACGCCAGACTCCCGGAGGGTCGC GCGGCCGCCGCCCATTGGCGCCGAGGTCCCCGACGTCACCGCGACCCCCGCGAGGCTGCT TTTCTTCGCGCCCACCCGCCGCGCGGCGCCGCTTGAGGAGATGGAAGCCCCGGCCGCTGA CGCCATCATGTCGCCCGAAGAGGAGCTGGACGGGTACGAGCCGGAGCCTCTCGGGAAGCG GCCGGCTGTCCTGCCGCTGCTGGAGTTGGTCGGGGAATCTGGTAATAACACCAGTACGGA CGGGTCACTACCCTCGACGCCGCCGCCAGCAGAGGAGGAGGAGGACGAGTTGTACCGGCA GTCGCTGGAGATTATCTCTCGGTACCTTCGGGAGCAGGCCACCGGCGCCAAGGACACAAA GCCAATGGGCAGGTCTGGGGCCACCAGCAGGAAGGCGCTGGAGACCTTACGACGGGTTGG GGATGGCGTGCAGCGCAACCACGAGACGGCCTTCCAAGGTAAGGGGGTTCATTAATCGCC AAGGCCTCACTCCCTTTTTTCCATCTCTCCCCGGACTCACCCGCCAAGGGTGGGTTGGAA ACCGAAACGAGTCAGTGTTGAAACGTGTCTCATCCTATTCCTGAAGCCAGAATATTCTGG CCATGAGTCATTGTTTCCGCCCATCTTGATTCTTTTGGAAATGGCAGCTCTTGTTCAAAG ACCGGAAAGGGTGGGATGTCAATTTCAAGTGGGGTCAACCTGAGTTCTGTAAATCCCAGT AGCGATTTTCCCGCCGCGGGTGGGCAGGCGAATCTTGCGCCGGTTTAGACAAAGGAGGCC GTGAGGACCTGCATGCTTTTCTTTCTCAGGCATGCTTCGGAAACTGGACATCAAAAACGA AGACGATGTGAAATCGTTGTCTCGAGTGATGATCCATGTTTTCAGCGACGGCGTAACAAA CTGGGGCAGGATTGTGACTCTCATTTCTTTTGGTGCCTTTGTGGCTAAACACTTGAAGAC CATAAACCAAGAAAGCTGCATCGAACCATTAGCAGAAAGTATCACAGACGTTCTCGTAAG GACAAAACGGGACTGGCTAGTTAAACAAAGAGGCTGGGTAAGTTTGCCTTAAGGATGAAA GGGGCCTTGGAGTGGAAGTAGAATGAAGGATTTTTTTTAGAGAGGTGGGGATATCTAAAG GTTTTTATGACGCACGGCTGTTTGCAGGCTCTAACTAAAGGACCATTGTTTATTTGATGT TGATTTAAGTAGTGGATCCTTAGAGATAGTGGTATGGCGGTCTTGAATTGTATCAAAAAT CTTGGTTTTCTCTAGGCAATTTTTTGTTCCAATTCAGTTGAATACTCTTCAGTGGATTCA AACCATGAAAAAATAAGTCACCAGGGGAGGATAGCTGAAATAATTCCTAAGGCGGTGCCT GTTTTAATGGAGAAGATATGGGGTGGAGCCTGCGTTTTAAACAAACCCAGATCTGATGCA GGATGTACTTAACTACGTTGAGAAAAACTGATCTGCGCAATTGAGGCGTTACTGAAATAT TAGGTGGTGGAGATTTGAGAATAAGGGTTTTCGTCTTTTACCTCATGGGAACTCTGGAAG TCCTTTTGTTAGGATAAATCCTAATAAGACCAAGATAGTACTGTAAAATGAAGTTTAATT ATCATGGGTCCCCGCTTAAGAAACTGAAGAACTTATTTTCTTTTTTTGCCCCGGGGTGAA TAATAATTGGTTTACTATTGCTTTAGGGGGAAACCTTAGATATTTTAATTTACCTTCTCT CTGGATAGTAGTGTTGTAAGAGAGCAGAAACCCATACTTGAAAATGTGCTTTTCTTTTTT GTTTTCTAGGATGGGTTTGTGGAGTTCTTCCATGTAGAGGACCTAGAAGGTGGCATCAGG AATGTGCTGCTGGCTTTTGCAGGTGTTGCTGGAGTAGGAGCTGGTTTGGCATATCTAATA AGATAGCCTTACTGTAAGTGCAATAGTTGACTTTTAACCAACCACCACCACCACCAAAAC CAGTTTATGCAGTTGGACTCCAAGCTGTAACTTCCTAGAGTTGCACCCTAGCAACCTAGC CAGAAAAGCAAGTGGCAAGAGGATTATGGCTAACAAGAATAAATACATGGGAAGAGTGCT CCCCATTGATTGAAGAGTCACTGTCTGAAAGAAGCAAAGTTCAGTTTCAGCAACAAACAA ACTTTGTTTGGGAAGCTATGGAGGAGGACTTTTAGATTTAGTGAAGATGGTAGGGTGGAA AGACTTAATTTCCTTGTTGAGAACAGGAAAGTGGCCAGTAGCCAGGCAAGTCATAGAATT GATTACCCGCCGAATTCATTAATTTACTGTAGTGTTAAGAGAAGCACTAAGAATGCCAGT GACCTGTGTAAAAGTTACAAGTAATAGAACTATGACTGTAAGCCTCAGTACTGTACAAGG GAAGCTTTTCCTCTCTCTAATTAGCTTTCCCAGTATACTTCTTAGAAAGTCCAAGTGTTC AGGACTTTTATACCTGTTATACTTTGGCTTGGTTTCCATGATTCTTACTTTATTAGCCTA GTTTATCACCAATAATACTTGACGGAAGGCTCAGTAATTAGTTATGAATATGGATATCCT CAATTCTTAAGACAGCTTGTAAATGTATTTGTAAAAATTGTATATATTTTTACAGAAAGT CTATTTCTTTGAAACGAAGGAAGTATCGAATTTACATTAGTTTTTTTCATACCCTTTTGA ACTTTGCAACTTCCGTAATTAGGAACCTGTTTCTTACAGCTTTTCTATGCTAAACTTTGT TCTGTTCAGTTCTAGAGTGTATACAGAACGAATTGATGTGTAACTGTATGCAGACTGGTT GTAGTGGAACAAATCTGATAACTATGCAGGTTTAAATTTTCTTATCTGATTTTGGTAAGT ATTCCTTAGGTTTTTCTTTGAAAACCTGGGATTGAGAGGTTGATGAATGGAAATTCTTTC ACTTCATTATATGCAAGTTTTCAATAATTAGGTCTAAGTGGAGTTTTAAGGTTACTGATG ACTTACAAATAATGGGCTCTGATTGGGCAATACTCATTTGAGTTCCTTCCATTTGACCTA ATTTAACTGGTGAAATTTAAAGTGAATTCATGGGCTCATCTTTAAAGCTTTTACTAAAAG ATTTTCAGCTGAATGGAACTCATTAGCTGTGTGCATATAAAAAGATCACATCAGGTGGAT GGAGAGACATTTGATCCCTTGTTTGCTTAATAAATTATAAAATGATGGCTTGGAAAAGCA GGCTAGTCTAACCATGGTGCTATTATTAGGCTTGCTTGTTACACACACAGGTCTAAGCCT AGTATGTCAATAAAGCAAATACTTACTGTTTTGTTTCTATTAATGATTCCCAAACCTTGT TGCAAGTTTTTGCATTGGCATCTTTGGATTTCAGTCTTGATGTTTGTTCTATCAGACTTA ACCTTTTATTTCCTGTCCTTCCTTGAAATTGCTGATTGTTCTGCTCCCTCTACAGATATT TATATCAATTCCTACAGCTTTCCCCTGCCATCCCTGAACTCTTTCTAGCCCTTTTAGATT TTGGCACTGTGAAACCCCTGCTGGAAACCTGAGTGACCCTCCCTCCCCACCAAGAGTCCA CAGACCTTTCATCTTTCACGAACTTGATCCTGTTAGCAGGTGGTAATACCATGGGTGCTG TGACACTAACAGTCATTGAGAGGTGGGAGGAAGTCCCTTTTCCTTGGACTGGTATCTTTT CAACTATTGTTTTATCCTGTCTTTGGGGGCAATGTGTCAAAAGTCCCCTCAGGAATTTTC AGAGGAAAGAACATTTTATGAGGCTTTCTCTAAAGTTTCCTTTGTATAGGAGTATGCTCA CTTAAATTTACAGAAAGAGGTGAGCTGTGTTAAACCTCAGAGTTTAAAAGCTACTGATAA ACTGAAGAAAGTGTCTATATTGGAACTAGGGTCATTTGAAAGCTTCAGTCTCGGAACATG ACCTTTAGTCTGTGGACTCCATTTAAAAATAGGTATGAATAAGATGACTAAGAATGTAAT GGGGAAGAACTGCCCTGCCTGCCCATCTCAGAGCCATAAGGTCATCTTTGCTAGAGCTAT TTTTACCTATGTATTTATCGTTCTTGATCATAAGCCGCTTATTTATATCATGTATCTCTA AGGACCTAAAAGCACTTTATGTAGTTTTTAATTAATCTTAAGATCTGGTTACGGTAACTA AAAAAGCCTGTCTGCCAAATCCAGTGGAAACAAGTGCATAGATGTGAATTGGTTTTTAGG GGCCCCACTTCCCAATTCATTAGGTATGACTGTGGAAATACAGACAAGGATCTTAGTTGA TATTTTGGGCTTGGGGCAGTGAGGGCTTAGGACACCCCAAGTGGTTTGGGAAAGGAGGAG GGGAGTGGTGGGTTTATAGGGGGAGGAGGAGGCAGGTGGTCTAAGTGCTGACTGGCTACG TAGTTCGGGCAAATCCTCCAAAAGGGAAAGGGAGGATTTGCTTAGAAGGATGGCGCTCCC AGTGACTACTTTTTGACTTCTGTTTGTCTTACGCTTCTCTCAGGGAAAAACATGCAGTCC TCTAGTGTTTCATGTACATTCTGTGGGGGGTGAACACCTTGGTTCTGGTTAAACAGCTGT ACTTTTGATAGCTGTGCCAGGAAGGGTTAGGACCAACTACAAATTAATGTTGGTTGTCAA ATGTAGTGTGTTTCCCTAACTTTCTGTTTTTCCTGAGAAAAAAAAATAAATCTTTTATTC AAA OMIM ID 159552