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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCM2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4171
Official gene symbolMCM2
Full nameminichromosome maintenance complex component 2
Aliases,BM28,CCNL1,CDCL1,D3S3194,KIAA0030,MGC10606,MITOTIN,cdc19,
Gene summaryThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q21
Gene position127317253 - 127341279  Map Viewer
Gene orientationplus
Gene size24027 bp
Gene sequence
OMIM ID116945