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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MCM2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000216 M/G1 transition of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0006260 DNA replication IEA GO:0006260 DNA replication TAS GO:0006268 DNA unwinding involved in replication IEA GO:0006270 DNA-dependent DNA replication initiation IEA GO:0006270 DNA-dependent DNA replication initiation IMP GO:0006271 DNA strand elongation involved in DNA replication TAS GO:0006334 nucleosome assembly IEA GO:0007049 cell cycle TAS cellular_component GO:0000785 chromatin IDA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005664 nuclear origin of replication recognition complex IEA GO:0042555 MCM complex IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0003688 DNA replication origin binding IEA GO:0004386 helicase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016787 hydrolase activity IEA GO:0042393 histone binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for MCM2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ORC1L Two-hybrid physical 12614612 ORC4L Two-hybrid physical 12614612 MCM5 Two-hybrid physical 12614612 CDC7 Two-hybrid physical 12614612 ORC2L Two-hybrid physical 12614612 RPA2 Two-hybrid physical 12614612 DBF4 Two-hybrid physical 12614612 AKAP8 Two-hybrid physical 12740381 MCM2 Two-hybrid physical 12614612 RPA1 Two-hybrid physical 12614612 RPA3 Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 MCM3 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 16189514 ATM Biochemical Activity physical 15210935 ATR Biochemical Activity physical 15210935 AKAP8 Reconstituted Complex physical 12740381 AKAP8 Reconstituted Complex physical 12740381 AKAP8 Affinity Capture-Western physical 12740381 AKAP8 Affinity Capture-Western physical 12740381 MCM6 Reconstituted Complex physical 12694531 MCM7 Reconstituted Complex physical 12694531 MCM4 Reconstituted Complex physical 12694531 MCM6 Reconstituted Complex physical 12694531 MCM7 Reconstituted Complex physical 12694531 MCM6 Two-hybrid physical 12694531 MCM3 Two-hybrid physical 12614612 MCM4 Two-hybrid physical 12614612 MCM5 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 12614612 MCM7 Two-hybrid physical 12614612 MCM4 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 12614612 MCM7 Two-hybrid physical 12614612 ORC1L Two-hybrid physical 12614612 ORC2L Two-hybrid physical 12614612 ORC4L Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 CDC7 Two-hybrid physical 12614612 RPA1 Two-hybrid physical 12614612 ORC2L Affinity Capture-Western physical 12614612 RPS4X Two-hybrid physical 16169070 MPP3 Two-hybrid physical 16169070 PHC2 Two-hybrid physical 16169070 GNB5 Two-hybrid physical 16169070 MOBKL3 Two-hybrid physical 16169070 MCM4 Co-purification physical 10567526 MCM6 Co-purification physical 10567526 MCM7 Co-purification physical 10567526 MCM7 Affinity Capture-Western physical 9099751 TCEA2 Reconstituted Complex physical 12392551 TBP Reconstituted Complex physical 12392551 CCNC Reconstituted Complex physical 12392551 MCM5 Affinity Capture-Western physical 11248027 MCM4 Affinity Capture-Western physical 8798650 MCM6 Affinity Capture-Western physical 12207017 MCM7 Affinity Capture-Western physical 12207017 ING5 Affinity Capture-Western physical 16387653 BRCC3 Affinity Capture-MS physical 19615732 AIRE Affinity Capture-MS physical 20085707 DDA1 Affinity Capture-MS physical 20562859 PRKAG1 Affinity Capture-MS physical 20562859 UBA5 Affinity Capture-MS physical 20562859 HIST1H4A Affinity Capture-Western physical 19862764 HIST1H4A Affinity Capture-MS physical 19862764 HIST1H4A Affinity Capture-Western physical 19862764 MCPH1 Reconstituted Complex physical 19525936 SSRP1 Affinity Capture-Western physical 16902406 MCM4 Affinity Capture-Western physical 16902406 CDC7 Biochemical Activity physical 16826239 MYST2 Biochemical Activity physical 16428461 MGMT Affinity Capture-Western physical 16226712 EMD Affinity Capture-MS physical 17620012 CCL2 Affinity Capture-Western physical 21383955 CCL2 Affinity Capture-Western physical 21383955 ASF1B Affinity Capture-Western physical 20227376 L3MBTL Affinity Capture-Western physical 21149733 L3MBTL Affinity Capture-Western physical 21149733 HDAC5 Affinity Capture-MS physical 21081666 C6orf167 Affinity Capture-MS physical 21055985 NFKBIL2 Affinity Capture-MS physical 21055985 SSRP1 Affinity Capture-MS physical 21055985 C6orf167 Affinity Capture-Western physical 21055985 C6orf167 Affinity Capture-Western physical 21055985 UBC Affinity Capture-MS physical 18781797