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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCM3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4172
Official gene symbolMCM3
Full nameminichromosome maintenance complex component 3
Aliases,HCC5,MGC1157,P1-MCM3,P1.h,RLFB,
Gene summaryThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p12
Gene position52149582 - 52128812  Map Viewer
Gene orientationminus
Gene size20771 bp
Gene sequence
OMIM ID602693