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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MCM3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000216 M/G1 transition of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0006260 DNA replication IEA GO:0006260 DNA replication TAS GO:0006270 DNA-dependent DNA replication initiation IEA GO:0006271 DNA strand elongation involved in DNA replication TAS cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0005658 alpha DNA polymerase:primase complex TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IEA GO:0005813 centrosome IDA GO:0042555 MCM complex IDA GO:0043231 intracellular membrane-bounded organelle IDA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0004386 helicase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016787 hydrolase activity IEA

Protein-protein interaction details for MCM3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MCM2 Two-hybrid physical 12614612 MCM5 Two-hybrid physical 12614612 CDC45 Two-hybrid physical 12614612 DBF4 Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 ORC4L Two-hybrid physical 12614612 PNKP Affinity Capture-MS physical 17353931 ENSA Affinity Capture-MS physical 17353931 PAK2 Affinity Capture-MS physical 17353931 SNCG Affinity Capture-MS physical 17353931 WDR8 Affinity Capture-MS physical 17353931 PTP4A3 Affinity Capture-MS physical 17353931 MCM2 Two-hybrid physical 12614612 MCM7 Two-hybrid physical 12614612 MCM5 Two-hybrid physical 12614612 MCM7 Two-hybrid physical 12614612 ORC4L Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 DBF4 Two-hybrid physical 12614612 CDC45 Two-hybrid physical 12614612 RPA2 Two-hybrid physical 12614612 CDC7 Biochemical Activity physical 9250678 MCM3AP Two-hybrid physical 12226073 MCM3AP Affinity Capture-Western physical 10733502 MCM3AP Affinity Capture-Western physical 9712829 MCM3AP Two-hybrid physical 9712829 CDC6 Affinity Capture-Western physical 10464337 MCM7 Affinity Capture-Western physical 10464337 MCM7 Affinity Capture-Western physical 9099751 MCM7 Co-fractionation physical 11779870 MCM5 Affinity Capture-Western physical 11248027 CDC6 Co-fractionation physical 11046155 ORC2L Co-fractionation physical 11046155 PMS2 Affinity Capture-MS physical 17148452 HIST1H4A Affinity Capture-Western physical 19862764 LZTR1 Two-hybrid physical 20211142 SYF2 Two-hybrid physical 16951160 SYF2 Reconstituted Complex physical 16951160 SYF2 Reconstituted Complex physical 16951160 SSRP1 Affinity Capture-Western physical 16902406 MGMT Affinity Capture-MS physical 16226712 SMARCA5 Co-localization physical 15775975 CCL2 Affinity Capture-Western physical 21383955 CCL2 Affinity Capture-Western physical 21383955 HIF1A Affinity Capture-Western physical 21658608 HIF1A Affinity Capture-Western physical 21658608 EPAS1 Affinity Capture-Western physical 21658608 L3MBTL Affinity Capture-Western physical 21149733 YWHAQ Affinity Capture-MS physical 15161933 PPP2R1A Affinity Capture-MS physical 17540176 PPP2R1B Affinity Capture-MS physical 17540176 HDAC5 Affinity Capture-MS physical 21081666 C6orf167 Affinity Capture-MS physical 21055985 NFKBIL2 Affinity Capture-MS physical 21055985 SSRP1 Affinity Capture-MS physical 21055985 PSMA3 Affinity Capture-MS physical 22079093 MAPK6 Two-hybrid physical 21900206 SUMO1 Affinity Capture-MS physical 19596686 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572