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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCM7 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4176 Official gene symbol MCM7 Full name minichromosome maintenance complex component 7 Aliases ,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146, Gene summary The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] Location Chromosome: 7   Locus: 7q21.3-q22.1 Gene position 99699427 - 99690404  Map Viewer Gene orientation minus Gene size 9024 bp Gene sequence >MCM7:complement(37723247..37732270):Length=9024 CGCCCCTTCCCAGCCCCAAGGGTCTAGGATACAGTCTTTGTAGATGAGCGGGTCCCCCTT GGAGGACAGAATGAAGAATTGGGAAATCATGGCCGTTCTGGAGAGTAGACAAGAAGACGG CGAAAGTCGGGCCTGCCCCGCCCTGCGGCCCCGGAACAAAAGAACGCGTGTGCGCTGGCC CTTTAAGAGCGATTCTCCTCCGCCCGCGCCAGCTCGGACCGCGGGAAACCCGGCGCCTGC ACTACCCCGCCCGGAGATTCCCTTCCGACGCCCGCACCGCCTCCCCGTCACTCATTCTAG GCCCGCACGGTGATTGGCTTGCGGCTAGCGGGAGGTGAAGAAGGCCGCCTTGTCCGATTG GCCCGCACGCAGTGGCGCCGGTCACGTGGGGGGCGACGTTTCGCGCCAATTTCGGTTGGC CGGCCACAGTCCACCGCGCGGAGATTCTCAGCTTCCCCAGGAGCAAGACCTCTGAGCCCG CCAAGCGCGGCCGCACGGCCCTCGGCAGCGATGGCACTGAAGGACTACGCGCTAGAGAAG GGTACGGGTCTACGAGCCCGGGAGGGCGTCCTGCGCGGGGAGCCTCCCGGGGAACACCTG TTGGTGTGAGCTGGGGTCTTGGGGGACCGGGGTCGGCGGGTTCTGGGGTGCGCGAGGCCA GAGGCAGGGTCGAGCTGCGGCCTGGCTAAGGCCCACGGGGCCTGGGAAGCGTGCGGGGGG CCATCGATGTTGAAGAAAAGCTAGTAATCCCACCTGGTAAAGGTGTTAGGGTCGTGGGGT TGGGGGCTTGGGGGCGCGCTAACCCGGCTGGGGGCTGCACAGGGAAAAGTCGCGCCCAGG ACCTCAGGAGAGTCTTAAGGGCTCTGGGCTCCCGTGCCCGCTTTCCTTCGCGCTTTTGGG CATTCCCAGGTTCCCGCGCCCTCCCCAGGCGCGCGTAGGCCCCGGGGGCGGGCAGGCCGG GGCCGCTGCGCGCCGGGATTGGCCGTTTGAGGCCGCCCTCCGAGCGGAAGTGGAGCCGGG CGGAAGTGGCGCGAGGAGGCTGGAGGGAGTGTCGTGTAAACAGTGTCCTTCCGCGCGGCG GCCGCGGAGAGAGCTGCGGCCCGGGGGGGCGTGCCTGGGATCCGGAGCTTCGCTCGGGCC CGGGAAAGGCGGCAGTGGGCTGGGATCGCGGTGTCTCTGGGTGTGATGGCCAATGGCTGG ACTGGCTCCCGCCCTGGGCGGAGGAATCCCGAGCTGTGAAGCGGCTGGAATCCGGGCCCA TGTGCTTCTTTGTTTACTAAGAGCGGAAGCGATGGCGGGAGCGGGGGTGGGGTGCGGTGG CGGGGTGCGGTGGCGGAGGTCCCGGTGAAATCAGGGGCTAAGGGGACCCAAAGAAGGCGG GGGATCATAGGGGTGGAAAGAAAGCTGAGAACCTTGAGACCGGAGTGTGAGGGGCCAACG GGGAAGGGCGCTAGAATTTTAAACTAAAGTAGGGACCGGAATTCCCCTGGGGAGATGTTG GATGGCCCTGTGCACTGCCACGGGCTCTTTATTCTTCGCTGGTTAGAAACAGACTTGTGA AAAAGAGTTATGCCCACTTTGGGGAGACTTCGGTAGGTTTATTTAAATGCTCATATTATT AATTAGTTCATAGGTCGTGTTTTAAGCGAAAATGGGTATCTAAGATTTGTCTTAAAGTTT GTGTCTTACGGTTTTACATTTCATGTTACAGAAAAGGTTAAGAAGTTCTTACAAGAGTTC TACCAGGATGATGAACTCGGGAAGAAGCAGTTCAAGTATGGGAACCAGTTGGTAAGTCTA AGATTGGGTAAAGGGAATGGGGAGCGGGGTGCTTAAGGAGCCATAAGCAGCAGCTTGGCT TGTTTTATTAAAGACATAACAATTAGAGGGTTTGAGGGCTGAAAAGCGAGTATCGCTCTG TGTGGCGCTGCGTTCTCCCCTGTGGATGCCCAGAGCCTGTGCTGAGTTCTCAGTGATGCA TTTTCACATATGAACACTGGTGAGCAAAGTGAATGTGGCTCTGAGGTGTTTCTGTCTCTT CCCCACTTGAGGTTCGGCTGGCTCATCGGGAACAGGTGGCTCTGTATGTGGACCTGGACG ACGTAGCCGAGGATGACCCCGAGTTGGTGGACTCAATTTGTGAGAATGCCAGGCGCTACG CGAAGCTCTTTGCTGATGCCGTACAAGAGCTGCTGCCTCAGTACAAGGAGAGGGAAGTGA GTGGTTAGAGAACAATGGCAAACAAAGGGCGAGGCGTTTAAGCTTCTGTAGAGAGGCTGC TCAGATACTGATGTTTTCTGAGCAGGCAGAAAGGAGGGGCACTTCTGCCTGGTGTTCTCT GTGCTCTCCTTTCCCCATCCTGTTGCTCTTTTTTTTTTTTTTTTTTGTTCTTCTCCTTTA GGTGGTAAATAAAGATGTCCTGGACGTTTACATTGAGCATCGGCTAATGATGGAGCAGCG GAGTCGGGACCCTGGGATGGTCCGAAGCCCCCAGAACCAGTACCCTGCTGAACTCATGCG CAGATTGTGAGTGGTCTCTGTCGGGAAAGATGTAGGGATTGGTTCTCCAGGATCTTGTTT GTGACTGTTTTCTCCCCTTAGTGAGCTGTATTTTCAAGGCCCTAGCAGCAACAAGCCTCG TGTGATCCGGGAAGTGCGGGCTGACTCTGTGGGGAAGTTGGTAACTGTGCGTGGAATCGT CACTCGTGTCTCTGAAGTCAAACCCAAGATGGTGGTGGCCACTTACACTTGTGACCAGTG TGGGGCAGAGACCTACCAGCCGGTACGTGTGGAGCAAGAAGCAGGAAAGCACTTACCCAT TAGTTGTTTTGTAGAGATTAATTTGATCCTGTGATGCCTATTGTTTTATTTGGTTGTAAA AGTTGCCTGTGTGTTCGCCTTTCATTCTTGGGTATGTAGTGGTCTTTCTACCTATTTTCT GGGTGTTTGTTGTTGACCCAGAGTAAGTTCAGAGGGTTCTTGACACTTACAAGATGTCTG CCATGAAGAGAAAATGTGATTCAAAGGACCGACCCAATGGGGCTCTTTTCCTTCTGAGTT CCTTTGGTGTTTCTGTTCTCACATCCTAGATCCAGTCTCCCACTTTCATGCCTCTGATCA TGTGCCCAAGCCAGGAGTGCCAAACCAACCGCTCAGGAGGGCGGCTGTATCTGCAGACAC GGGGCTCCAGATTCATCAAATTCCAGGAGATGAAGATGCAAGAACATGTGAGTTTGGGGT ACGTGGCCCTGGGCAGGTGGATCGGGAGTCCACTTGAATCCTGTAGTCACTTGTGGAATG GCAGGAAGAAAGAAGAACAAAAGAGGGAAGTGCAGGAGGGAGGTGGAACTAGAATTTCCT GGGAGCCTTGGGAAGGGGAAAGGAGGTCTCAGCACCCCTGCTGTGGGCTTGTCTGTGGCT GGGTAGCCTGGGAGCCTTTGAGTGGGATGCCTAGGGAGGGAAGGTTGGGTCCTTGTCCAT TTCTCCTAGTCTTATGTGCCTTTCCCTCCCCTAGAGTGATCAGGTGCCTGTGGGAAATAT CCCTCGTAGTATCACGGTGCTGGTAGAAGGAGAGAACACAAGGATTGCCCAGCCTGGAGA CCACGTCAGCGTCACTGGTATTTTCTTGCCAATCCTGCGCACTGGGTTCCGACAGGTGGT ACAGGTAAGGAAGAGTTTGACATGAGGAATGGATCATCCCCTTTTCCCTCACCTACTCAT TCTACCCACACAGAGAAAAGAGCAGCAAAACCCCAAACAAAACAGAACCCAGGGATTTGT CAAGAAATTGTTAGGGAATCCAGTGATGGGCAAGTTGAAGGGATTACATCTGTATCCTGG CATTTTCCTGCCCAAGGGTTTACTCTCAGAAACCTACCTGGAAGCCCATCGGATTGTGAA GATGAACAAGAGTGAGGATGATGAGTCTGGGGCTGGAGAGCTCACCAGGGAGGAGCTGAG GCAAATTGCAGGTGAGGGGCAGGGGAGAGAGAGGAAATTCCGTTTACATCCTAGCTCCCT TTTCCCCCAGAAAATAAAACAACCTTAACTTCTCTACAGAGGAGGATTTCTACGAAAAGC TGGCAGCTTCAATCGCCCCAGAAATATACGGGCATGAAGATGTGAAGAAGGCACTGCTGC TCCTGCTAGTCGGGGGTGTGGACCAGTCTCCTCGAGGCATGAAAATCCGGGGTAAGAAGA AACAAGGGAGAGGCTCAGGGTGGATGAAGTCATTTAGGAGGAAAAAAGGATGACAAGTGT CCCTGTAGGTCACAGTATGAGTGGACATCTTGCCTTCGTGGACACAGGGAGGGCTTAGAA ATAGTGCTGGGTGTTAGGGGTAGGCAGAACTCAAAATTGCTCTGTTGTTGGCCAAGCACT GGGAGAAGAGTCATTCCAGGGCTGCCTTCCCTTCCTCCAGGCAACATCAACATCTGTCTG ATGGGGGATCCTGGTGTGGCCAAGTCTCAGCTCCTGTCATACATTGATCGACTGGCGCCT CGCAGTAAGTAGTTGGGCTTTGCGGGAGGTGAATATAGTGACAGACAGGACCACAGTGTT TATTCAAAAAGTAGGGGTGCATGTTTGCTCACGCCTGTAATCCCAATGCTCTGAGAGGCT GAGGCAGGAGAATCATTTGAGGCGAGGATTTTGAGACCGCTTCCATGTCTACTAAAAAGT TTTGTTTTTGTTTTTGTTTTTTTTGAGATAGAGGCTTGCTCTTTCGCCCAGGCCGGAGTG CAGTGGCGCTATCTCGGTTCACTGCAAGCTCCACCTCCTGGGGTCACGCCATTCTCCTGC CTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCTGGCTAATTCTTTG TATTTTTAATAGAGACGGGGTTTCACCGTGTTAGCCAGATGGTCTCGATATCCTGACCTC GTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCC GGCCTAAAAAGTTTTTTTTGTTGTTTGGGTATTGTTTTGTTTTTTGTTTTTTTTGAGACG GAGTCTCAGTCACCCAGACTGGAGTGCAATGGCATGGTCTTGGCTCACTGCAACCTCTGC CTCCCAGGTTCAAGCAATTCTCCTGCTTCGGCCTCCCGAGTAGCTGGGACTACAGGCGCG TGCCACCACACTTGGCCACTTTTTGTATTTTTAGTAGAGACAGGGTTTACTGTGTTGGGC AGGCTGGTCTCGAACTCCTGACCTCGTGATCTGCCCGCCTTGTTATCGGCCTCCGAAAGT GCTGGGATTAGAGGAGTTAGCCACTGCGCCCGGCCTCTACTAAAAAGTTTTAAAAATTGG TTGGGTGTGGTAGTGAGTGCCTATAGTCTCAGTTACTTGGGAGGCTGAGGCCGGAGGATG GCTTGAGCCCAGGAGCCAAGGTTTCAGTGAGCCACAGTTGTGTTCTGAAGAGAACCAGTG GGAGGGGAAGGGGGACATTGCCAGTGCCCCACAGATCCTCGGGCATCTCAAGAAGGCCTG GTGGAGGGAGTGGAATGATCCCAGCGCAGGCCTCGCCTCCCTGGCCCGTTTGTTGTCTTT TGCTTGTTCTCTTTCTTGTTCTTTCTCTCTCATGGTTCCTTATTTCTTCTCTTCCAGGCC AGTACACAACAGGCCGGGGCTCCTCAGGAGTGGGGCTTACGGCAGCTGTGCTGAGAGACT CCGTGAGTGGAGAACTGACCTTAGAGGGTGGGGCCCTGGTGCTGGCTGACCAGGGTGTGT GCTGCATTGATGAGTTCGACAAGATGGCTGAGGCCGACCGCACAGCCATCCACGAGGTCA TGGAGCAGCAGACCATCTCCATTGCCAAGGCCGGCATTCTCACCACACTCAATGCCCGCT GCTCCATCCTGGCTGCCGCCAACCCTGCCTACGGGCGCTACAACCCTCGCCGCAGCCTGG AGCAGAACATACAGCTACCTGCTGCACTGCTCTCCCGGTTTGACCTCCTCTGGCTGATTC AGGACCGGCCCGACCGAGACAATGACCTACGGTGAATGAAGCTCAACACCCAAAGAGAGG TCCCCTGTAATGATCTGTGTAGGGAGGAGGAGAGGTGAATCAGAAAACAAATTCCACGCT CCTGGAAACCCCAGAGCCTCCCCTTTGCAGCAGGGGCTGGTCCATGGTTCTCAGGGAAAT GGTGGGTTGGGGCTGAAATGCTGATGAGGATTTCCCGGGAAAGCTTGTCCCTCCTACACT GTGAGGAAGTGGCAGAGCCAAAGGAGGGACACCTAAGAGGACATGGGTGCGTAGCCCTAA AAAGGGTGTTCCTTCTAACCTTCCCTCTGTCCAGGTTGGCCCAGCACATCACCTATGTGC ACCAGCACAGCCGGCAGCCCCCCTCCCAGTTTGAACCTCTGGACATGAAGCTCATGAGGT AGGAGAGCTGGGTGCGGGTGGGCAAACGTTGGCGTGGGCCGTGCGAGCCTCCTGAAAAAG TGCTTATTAGTCTTAGGGTGTGTGTTTTTCACACCACCACTTCCCGCTACAGACATGTCC AGAGCCTCAGATCAGCTTTTAAGTGGAAAATTCCACACTTCATATCATAGGGACACAGGA AATTTTGTTTCCTACACTATTTATTTTTTTTGAGACGAAGTCTTGCTCTGTCACCCAGGC TGGAGTGTAGTGATCTCAGCTCTCTGCAACCTCTGCCTCCCAGATTCAAGCGATTCTCCT GCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACGCCACCACGCCTGGTTAATTTTT TGTATTTTAGTAGAGAGCAGTTTCACCATGTTGGCCAGGATGCCCACCTCTGCCTCCCAA AGTGCTGGGATTACAGGCATGAACCACTGCTCCTGGCCCACAAAAATATTTTTAATAAAA TTACCTTCAGGTTATGTGTATCAGTTGTATATGAAATACAGGTGAATTTCATGTTTAGAC TGGAGTCCCATCCCCAAGCTATCTCATGCATATGCAAATACTCCAAAATTTAAAGTTTAA AACACCTGCTCCCAGGCATTCTGGATGATAATCTCTATCGCTATTTTCCCATGAGCCTCC AGTGTTCTTTCCGGTTTTTACTCCCTTTTAAATATTCTGTAAACAGTTCTCTTTAAATAA AATATATGTTTTGCCATGTCATGCGCTCAGAGGAGGGGTCTGGATCCTCTCTTAATGACA GACGGATTTGTCTTACAAAGGCCATTTTCCCGAAAAAAATAGGAAATAACTTGGAGGATA CTGGTGGGGGCTATACGTTTGGTGAAATCCATCAGTGATATTCAAGCCAAGCAAATAATC ACCCACTAATTTGTGTTTTCCACTTAAAATTCTTGGAGGGGACCATGTTAAATGGGGAGC CCTGGTACAGAAAACAACATGGGCTCATATTCACTCCCTTCCCCATCTCCCTCTTCTGCT TCCCCATGAACCTTCCCCCACAGGCGTTACATAGCCATGTGCCGCGAGAAGCAGCCCATG GTGCCAGAGTCTCTGGCTGACTACATCACAGCAGCATACGTGGAGATGAGGCGAGAGGCT TGGGCTAGTAAGGATGCCACCTATACTTCTGCCCGGACCCTGCTGGCTATCCTGCGCCTT TCCACTGCTCTGGTAAGTGCCCAAATTGCTGGAGGGCCATCTGTTTTGACCCTTAAAGGG GTAGCTCCTTACCGTGCTCTCATTGCCGCCTCCCCACCTCCCGCTCCAGCCCTGCCGGGG CTAAAGTGCTGACAGTGCAGATAGTGGTCCTCTCCGTGCTACCGCACTGTGGGTACTTGC TGCTCCAGCAGGGCACGCACAGCGTCCGTGGAGGGAAAGGCCTTTTCCCCACTTCTTAAC CTTCACTGAGAGGGTGGTTGGGGTCTGTTTCACTCCATGTGTCCTAGATCCTGTGCTACA GACCTTCCTTTCTGTCCTCCCGTCTTGGACCTCAGTCCTGGGGGCTCCAAAGTGCTGTTC GTGCAGGTAGTGTGATTACCCAACCTACTGCTGAGCTAGCACTTCCCGAGCCCCCGGGAC ACGTTCTCTCTGCCAATTGTCTTCTTGGCTGAGCTCCCCAAGCTCCATCTGTCATGCTGG GGAGCCCAGTGGCGTTCAAAAGGGTCTGGTCTCCCTCACAGGACAGCTGAACTCCGGGAC TGGCCAGTGTTGAGAGGCGGAGACTTGGGCAATTGCTGGACGCTGCCCTGGGCATTGCAC TTGTCTCGGTCTGACAGTGCCGGCCCAACACTGCGGATGCTGGGGGGAGGGGGGATTCCA CTCCTGTTTTGTGAGTAGGCGACCCATGGGCTGCCCAGCCTTAAAGCCAGAACAAGGGTG TCCCCTGACCTCGTTCCACTGCCCTCCTCCCGTTCCCATCTTTCCCCCCTACCTTCCCCT TAGGCACGTCTGAGAATGGTGGATGTGGTGGAGAAAGAAGATGTGAATGAAGCCATCAGG CTAATGGAGATGTCAAAGGACTCTCTTCTAGGAGACAAGGGGCAGACAGCTAGGTGAGTG GTTTAGTGAAGGACAAAGCTGTGTCACTTTGTCTTCTGTGGCCATGTGTCTGAGGTTGGC CTCAATTCTAACACTGGCCACCATTGTTCTCTGTTGATGTCGAGCATTCCTGTTTGTATC CTGACCTTACACACCCACTCATTTCCTTCAGGACTCAGAGACCAGCAGATGTGATATTTG CCACCGTCCGTGAACTGGTCTCAGGGGGCCGAAGTGTCCGGTTCTCTGAGGCAGAGCAGC GCTGTGTATCTCGTGGCTTCACACCCGCCCAGTTCCAGGCGGCTCTGGATGAATATGAGG AGCTCAATGTCTGGCAGGTCAATGCTTCCCGGACACGGATCACTTTTGTCTGATTCCAGC CTGCTTGCAACCCTGGGGTCCTCTTGTTCCCTGCTGGCCTGCCCCTTGGGAAGGGGCAGT GATGCCTTTGAGGGGAAGGAGGAGCCCCTCTTTCTCCCATGCTGCACTTACTCCTTTTGC TAATAAAAGTGTTTGTAGATTGTC OMIM ID 600592