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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MCM7 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000216 M/G1 transition of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0006260 DNA replication IEA GO:0006260 DNA replication TAS GO:0006268 DNA unwinding involved in replication IEA GO:0006270 DNA-dependent DNA replication initiation IEA GO:0006271 DNA strand elongation involved in DNA replication TAS GO:0006974 response to DNA damage stimulus IMP GO:0008283 cell proliferation IEA GO:0042325 regulation of phosphorylation IMP cellular_component GO:0000785 chromatin TAS GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0042555 MCM complex IDA GO:0042555 MCM complex IMP molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0003677 DNA binding TAS GO:0003678 DNA helicase activity IEA GO:0003697 single-stranded DNA binding IEA GO:0004003 ATP-dependent DNA helicase activity IDA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016787 hydrolase activity IEA GO:0017111 nucleoside-triphosphatase activity IEA

Protein-protein interaction details for MCM7 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ORC1L Two-hybrid physical 12614612 RB1 Two-hybrid physical 9566894 DBF4 Two-hybrid physical 12614612 CDC7 Two-hybrid physical 12614612 ORC3L Two-hybrid physical 12614612 RPA1 Two-hybrid physical 12614612 FHL2 Two-hybrid physical 10649446 ORC2L Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 RBM8A Two-hybrid physical 16189514 MBIP Two-hybrid physical 16189514 MCM7 Two-hybrid physical 12614612 NEK6 Affinity Capture-MS physical 17353931 GIPC1 Affinity Capture-MS physical 17353931 TH1L Affinity Capture-MS physical 17353931 GSTK1 Affinity Capture-MS physical 17353931 PELO Affinity Capture-MS physical 17353931 CNOT8 Affinity Capture-MS physical 17353931 TRAF6 Affinity Capture-MS physical 17353931 MYC Affinity Capture-MS physical 17353931 ATR Affinity Capture-Western physical 15210935 MCM8 Affinity Capture-Western physical 12771218 MCM2 Reconstituted Complex physical 12694531 MCM4 Reconstituted Complex physical 12694531 MCM6 Reconstituted Complex physical 12694531 MCM2 Reconstituted Complex physical 12694531 MCM7 Reconstituted Complex physical 12694531 MCM2 Two-hybrid physical 12614612 MCM3 Two-hybrid physical 12614612 MCM5 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 12614612 MCM2 Two-hybrid physical 12614612 MCM3 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 12614612 ORC1L Two-hybrid physical 12614612 ORC2L Two-hybrid physical 12614612 ORC3L Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 CDC6 Two-hybrid physical 12614612 CDC7 Two-hybrid physical 12614612 DBF4 Two-hybrid physical 12614612 CDC45 Two-hybrid physical 12614612 CDC6 Two-hybrid physical 12614612 CDC45 Two-hybrid physical 12614612 RPA1 Two-hybrid physical 12614612 CDC6 Affinity Capture-Western physical 12614612 CDC45 Reconstituted Complex physical 10518787 ATRIP Affinity Capture-Western physical 15210935 RB1 Reconstituted Complex physical 9566894 RBL2 Reconstituted Complex physical 9566894 RBL1 Reconstituted Complex physical 9566894 RB1 Two-hybrid physical 9566894 CDC6 Affinity Capture-Western physical 10464337 CDC6 Affinity Capture-Western physical 10464337 MCM3 Affinity Capture-Western physical 10464337 UBE3A Reconstituted Complex physical 9852095 UBE3A Affinity Capture-Western physical 9852095 MCM2 Co-purification physical 10567526 MNAT1 Two-hybrid physical 11056214 MNAT1 Reconstituted Complex physical 11056214 MNAT1 Affinity Capture-Western physical 11056214 CCNH Affinity Capture-Western physical 11056214 CDK7 Affinity Capture-Western physical 11056214 MCM4 Affinity Capture-Western physical 9099751 MCM5 Affinity Capture-Western physical 9099751 MCM6 Affinity Capture-Western physical 9099751 MCM3 Affinity Capture-Western physical 9099751 MCM2 Affinity Capture-Western physical 9099751 MCM3 Co-fractionation physical 11779870 MCM5 Affinity Capture-Western physical 11248027 MCM10 Co-fractionation physical 11095689 MCM4 Affinity Capture-Western physical 8798650 MCM6 Affinity Capture-Western physical 12207017 MCM4 Affinity Capture-Western physical 12207017 MCM2 Affinity Capture-Western physical 12207017 CDT1 Reconstituted Complex physical 18162579 RECQL5 Affinity Capture-MS physical 19270065 IKBKG Reconstituted Complex physical 20098747 HIST1H4A Affinity Capture-MS physical 19862764 HIST1H4A Affinity Capture-Western physical 19862764 CDC45 Affinity Capture-Western physical 16912045 RB1 Affinity Capture-Western physical 16912045 SSRP1 Affinity Capture-Western physical 16902406 SUV420H2 Affinity Capture-MS physical 19486527 HIST3H3 Affinity Capture-MS physical 20953179 CCL2 Affinity Capture-Western physical 21383955 CCL2 Affinity Capture-Western physical 21383955 HIF1A Affinity Capture-Western physical 21658608 HIF1A Reconstituted Complex physical 21658608 EPAS1 Affinity Capture-Western physical 21658608 TCEB1 Reconstituted Complex physical 21658608 VHL Reconstituted Complex physical 21658608 VHL Affinity Capture-Western physical 21658608 UBC Affinity Capture-MS physical 16335966 TERF1 Affinity Capture-MS physical 20811636 TERF2 Affinity Capture-MS physical 20811636 UBC Affinity Capture-MS physical 16196087 MYC Affinity Capture-MS physical 17314511 MYC Two-hybrid physical 17314511 MYC Affinity Capture-Western physical 17314511 L3MBTL Affinity Capture-Western physical 21149733 HDAC5 Affinity Capture-MS physical 21081666 C6orf167 Affinity Capture-MS physical 21055985 NFKBIL2 Affinity Capture-MS physical 21055985 SSRP1 Affinity Capture-MS physical 21055985 SUMO1 Affinity Capture-MS physical 19596686 UBC Affinity Capture-MS physical 20639865 UBC Affinity Capture-MS physical 22108332 UBC Co-purification physical 17623298 UBC Affinity Capture-MS physical 18781797 LRDD Affinity Capture-MS physical 21415862 UBC Affinity Capture-MS physical 21987572