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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MYD88 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4615 Official gene symbol MYD88 Full name myeloid differentiation primary response gene (88) Aliases ,MYD88D, Gene summary This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq] Location Chromosome: 3   Locus: 3p22 Gene position 38179969 - 38184513  Map Viewer Gene orientation plus Gene size 4545 bp Gene sequence >MYD88:38119969..38124513:Length=4545 AGATTCCTACTTCTTACGCCCCCCACATCACCCGCCTCGAGACCTCAAGGGTAGAGGTGG GCACCCCCGCCTCCGCACTTTTGCTCGGGGCTCCAGATTGTAGGGCAGGGCGGCGCTTCT CGGAAAGCGAAAGCCGGCGGGGCGGGGCGGGTGCCGCAGGAGAAAGAGGAAGCGCTGGCA GACAATGCGACCCGACCGCGCTGAGGCTCCAGGACCGCCCGCCATGGCTGCAGGAGGTCC CGGCGCGGGGTCTGCGGCCCCGGTCTCCTCCACATCCTCCCTTCCCCTGGCTGCTCTCAA CATGCGAGTGCGGCGCCGCCTGTCTCTGTTCTTGAACGTGCGGACACAGGTGGCGGCCGA CTGGACCGCGCTGGCGGAGGAGATGGACTTTGAGTACTTGGAGATCCGGCAACTGGAGAC ACAAGCGGACCCCACTGGCAGGCTGCTGGACGCCTGGCAGGGACGCCCTGGCGCCTCTGT AGGCCGACTGCTCGAGCTGCTTACCAAGCTGGGCCGCGACGACGTGCTGCTGGAGCTGGG ACCCAGCATTGGTGAGGACGTCCCCTTCCTGGCCTCGTACCTGGGGGGTGAGGAGGCTGA CTTTCCGCGGCCTCAGCATCCTGTCTCCCATGGAGAGACCCCATTTCCTGCCTCGGGGGC CCGAAGAAGCCTGCAGAGGGAGAACCATGCGGGTCCCGTTCCTTCTTAATAACCGGTCGC GGTTATTAAGAAGGACTGGAGAAAGGTCCGGATAGGCGGAGATGGGAAGGAAGCAGCTTA GGCAGAGGCTTTCAGGTAGGGCCAGGAGTCAGAATCAGGCTTCTGTGGGGGCATCTGGGC TGTTTCAAGTAGAGCAACAGGACAGGTGGGGCGATTGACAGTGGACTGTCTTAGAAACCT CAAGTCCTGGGGAAATGCAGCCCTTCTTTCTACTCACTGGCACTTACATAATATACATGC ATAGGCGTTGGATACAGCCGCCCACAGACAGGCACACCTTGCTGAGTTGGAATCACTGCA CCATAACCAGTGGGTCTCCTGAGCCTTTCTGGCATGCCCAGCCCCTTGCTCACATCTGCC CTGGATCCCAGAAGAAGCAGACCTACCTTGGTACCATTCTTAGGATCCCTAGGAAGGGAC AGAGATACAAACCTGACTTTGATGGCCTTCCAGAAAGCCAGAACACCACTGACATCCCTT TGGGTCAGTTAGAGCCAGTGGGAGCTCAACTTCTCAGAGCCGTTGAGCTTCGCGTGGCAC CAGTGAACTGGGGAAGCCCTCTAGAACAACCCAGCCAGAGGAGGTGGGACAGCGGCTGGA TCCTGACTGTGGGTAAAGAGGTAGGCACTCCCAGGGAGGCTGCTTTACTCTGTCTCTTCC CCACAGAGGAGGATTGCCAAAAGTATATCTTGAAGCAGCAGCAGGAGGAGGCTGAGAAGC CTTTACAGGTGGCCGCTGTAGACAGCAGTGTCCCACGGACAGCAGAGCTGGCGGGCATCA CCACACTTGATGACCCCCTGGGTAAGGGTCCAATACTGTTCCCATGGGACAGGTGGAATA GGACATTGTGGTGTTAAGAGCATGGGTGTTTGAAGCAGATGGGCTGTGAGACCTTGGGCA AGTCACTTAATCTTTCTGAGCCTCAGTTTCCTCACCTAAGAAATGGAGATAATAGTCCTA CCTCTGGATTGCTGTGAGATGCTCATGAAATAATGTCTGTCTCGTGGTTAATCCAGAGCT TAGCCCCTGAGGTACTCATCTTTCCTCTCCTGGAAAGGGCACTTTCTCTGAGGAGTATCA TCTTGGGAAGGGTGCAGGGCCCAGGGTTGCCTAGGCAGGGGACTCTTGGCTGGATCCCTC CCAAGCCTTCCCATGGAGCTCTGACCACCACCCTTGTGCTCTGCACCCAGGGCATATGCC TGAGCGTTTCGATGCCTTCATCTGCTATTGCCCCAGCGACATCCAGTTTGTGCAGGAGAT GATCCGGCAACTGGAACAGACAAACTATCGACTGAAGTTGTGTGTGTCTGACCGCGATGT CCTGCCTGGCACCTGTGTCTGGTCTATTGCTAGTGAGCTCATCGAAAAGAGGTTGGCTAG AAGGCCACGGGGTGGGTGCGTGGATGCATGAAGCCCTGCCCTGGGGTCCAGATACTGGGC ATCTCCTCCTAGCTGTGCACTGTCCAGCCTGGGCACAGTGGGCCCTTCCTGAAGCTATTC CCAGGGGATATGCTGAACTAAGTTGCCACAGGACCTGCAGCCTGCCCACTCTCCCCTAGG TGCCGCCGGATGGTGGTGGTTGTCTCTGATGATTACCTGCAGAGCAAGGAATGTGACTTC CAGACCAAATTTGCACTCAGCCTCTCTCCAGGTAAGCTCAACCCTGCTCTGGCAAGAGAA TGAGGGAATGTGTAGGTGGGGCCTCTGGATTGTCAGCCTTCCCTCCCCAAGGACTGTGGA TGCAGTACCAAAGAACTGCTGAAGATCTCTGCACACCTGAGCATGTGTGCATGTGTGTGC CTTTTTGTGTGAGTGAATGTGTGCCAGGGGTACTTAGATGGGGGATGGCTGTTGTTAACC CTGGGGTTGAAGACTGGGCTTGTCCCACCATGGGGCAAGGGCCTGATGCCAGCATGGCAC CCCTTGGCTTGCAGGTGCCCATCAGAAGCGACTGATCCCCATCAAGTACAAGGCAATGAA GAAAGAGTTCCCCAGCATCCTGAGGTTCATCACTGTCTGCGACTACACCAACCCCTGCAC CAAATCTTGGTTCTGGACTCGCCTTGCCAAGGCCTTGTCCCTGCCCTGAAGACTGTTCTG AGGCCCTGGGTGTGTGTGTATCTGTCTGCCTGTCCATGTACTTCTGCCCTGCCTCCTCCT TTCGTTGTAGGAGGAATCTGTGCTCTACTTACCTCTCAATTCCTGGAGATGCCAACTTCA CAGACACGTCTGCAGCAGCTGGACATCACATTTCATGTCCTGCATGGAACCAGTGGCTGT GAGTGGCATGTCCACTTGCTGGATTATCAGCCAGGACACTATAGAACAGGACCAGCTGAG ACTAAGAAGGACCAGCAGAGCCAGCTCAGCTCTGAGCCATTCACACATCTTCACCCTCAG TTTCCTCACTTGAGGAGTGGGATGGGGAGAACAGAGAGTAGCTGTGTTTGAATCCCTGTA GGAAATGGTGAAGCATAGCTCTGGGTCTCCTGGGGGAGACCAGGCTTGGCTGCGGGAGAG CTGGCTGTTGCTGGACTACATGCTGGCCACTGCTGTGACCACGACACTGCTGGGGCAGCT TCTTCCACAGTGATGCCTACTGATGCTTCAGTGCCTCTGCACACCGCCCATTCCACTTCC TCCTTCCCCACAGGGCAGGTGGGGAAGCAGTTTGGCCCAGCCCAAGGAGACCCCACCTTG AGCCTTATTTCCTAATGGGTCCACCTCTCATCTGCATCTTTCACACCTCCCAGCTTCTGC CCAACCTTCAGCAGTGACAAGTCCCCAAGAGACTCGCCTGAGCAGCTTGGGCTGCTTTTC ATTTCCACCTGTCAGGATGCCTGTGGTCATGCTCTCAGCTCCACCTGGCATGAGAAGGGA TCCTGGCCTCTGGCATATTCATCAAGTATGAGTTCTGGGGATGAGTCACTGTAATGATGT GAGCAGGGAGCCTTCCTCCCTGGGCCACCTGCAGAGAGCTTTCCCACCAACTTTGTACCT TGATTGCCTTACAAAGTTATTTGTTTACAAACAGCGACCATATAAAAGCCTCCTGCCCCA AAGCTTGTGGGCACATGGGCACATACAGACTCACATACAGACACACACATATATGTACAG ACATGTACTCTCACACACACAGGCACCAGCATACACACGTTTTTCTAGGTACAGCTCCCA GGAACAGCTAGGTGGGAAAGTCCCATCACTGAGGGAGCCTAACCATGTCCCTGAACAAAA ATTGGGCACTCATCTATTCCTTTTCTCTTGTGTCCCTACTCATTGAAACCAAACTCTGGA AAGGACCCAATGTACCAGTATTTATACCTCTAATGAAGCACAGAGAGAGGAAGAGAGCTG CTTAAACTCACACAACAATGAACTGCAGACACAGCTGTTCTCTCCCTCTCTCCTTCCCAG AGCAATTTATACTTTACCCTCAGGCTGTCCTCTGGGGAGAAGGTGCCATGGTCTTAGGTG TCTGTGCCCCAGGACAGACCCTAGGACCCTAAATCCAATAGAAAATGCATATCTTTGCTC CACTTTCAGCCAGGCTGGAGCAAGGTACCTTTTCTTAGGATCTTGGGAGGGAATGGATGC CCCTCTCTGCATGATCTTGTTGAGGCATTTAGCTGCCATGCACCTGTCCCCCTTTAATAC TGGGCATTTTAAAGCCATCTCAAGAGGCATCTTCTACATGTTTTGTACGCATTAAAATAA TTTCAAAGATATCTGAGAAAAGCCGATATTTGCCATTCTTCCTATATCCTGGAATATATC TTGCATCCTGAGTTTATAATAATAAATAATATTCTACCTTGGAAA OMIM ID 602170