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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NPM1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4869
Official gene symbolNPM1
Full namenucleophosmin (nucleolar phosphoprotein B23, numatrin)
Aliases,B23,MGC104254,NPM,
Gene summaryThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
LocationChromosome: 5   Locus: 5q35
Gene position170814708 - 170837888  Map Viewer
Gene orientationplus
Gene size23181 bp
Gene sequence
OMIM ID164040