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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NPM1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006281DNA repairIDA
GO:0006334nucleosome assemblyIDA
GO:0006334nucleosome assemblyTAS
GO:0006886intracellular protein transportTAS
GO:0006913nucleocytoplasmic transportIDA
GO:0006913nucleocytoplasmic transportTAS
GO:0006916anti-apoptosisNAS
GO:0006950response to stressIMP
GO:0007098centrosome cycleIMP
GO:0007098centrosome cycleISS
GO:0007165signal transductionNAS
GO:0007569cell agingIMP
GO:0007569cell agingISS
GO:0008104protein localizationIDA
GO:0008285negative regulation of cell proliferationIMP
GO:0008285negative regulation of cell proliferationISS
GO:0010826negative regulation of centrosome duplicationIMP
GO:0032071regulation of endodeoxyribonuclease activityIDA
GO:0034080CenH3-containing nucleosome assembly at centromereTAS
GO:0042255ribosome assemblyTAS
GO:0044419interspecies interaction between organismsIEA
GO:0051092positive regulation of NF-kappaB transcription factor activityIMP
GO:0051259protein oligomerizationIDA
GO:0060699regulation of endoribonuclease activityIDA
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusISS
GO:0005654nucleoplasmIDA
GO:0005654nucleoplasmTAS
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISS
GO:0005813centrosomeIDA
GO:0005813centrosomeISS
GO:0005856cytoskeletonIEA
GO:0030529ribonucleoprotein complexIDA
GO:0031616spindle pole centrosomeIDA
molecular_function
GO:0003676nucleic acid bindingIEA
GO:0003713transcription coactivator activityIDA
GO:0003723RNA bindingIDA
GO:0005515protein bindingIPI
GO:0030957Tat protein bindingIDA
GO:0042393histone bindingIDA
GO:0042803protein homodimerization activityIDA
GO:0043023ribosomal large subunit bindingIDA
GO:0043024ribosomal small subunit bindingIDA
GO:0046982protein heterodimerization activityIMP
GO:0051059NF-kappaB bindingIDA
GO:0051059NF-kappaB bindingISS
GO:0051082unfolded protein bindingIDA
GO:0051082unfolded protein bindingISS

Protein-protein interaction details for NPM1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
TCERG1Affinity Capture-MSphysical15456888
LYARAffinity Capture-MSphysical17353931
USF2Affinity Capture-MSphysical17353931
HIST3H3Far Westernphysical11602260
SWAP70Co-purificationphysical9642267
HAND2Two-hybridphysical11812799
NCLAffinity Capture-Westernphysical8620867
NCLReconstituted Complexphysical8620867
OTUB1Affinity Capture-MSphysical18954305
AKT1Reconstituted Complexphysical18931307
AKT1Reconstituted Complexphysical18931307
AKT1Affinity Capture-Westernphysical18931307
AKT1Affinity Capture-Westernphysical18931307
UBCAffinity Capture-Westernphysical18319061
CDT1Affinity Capture-MSphysical18162579
CDT1Reconstituted Complexphysical18162579
RRP1BAffinity Capture-MSphysical19710015
GRB2Affinity Capture-MSphysical14968112
CENPFAffinity Capture-MSphysical14968112
CASKIN1Affinity Capture-MSphysical14968112
CDC14AAffinity Capture-MSphysical14968112
PIK3R1Affinity Capture-MSphysical14968112
NUP98Affinity Capture-MSphysical14968112
PPIDAffinity Capture-MSphysical14968112
GRB7Affinity Capture-MSphysical14968112
NCAPGAffinity Capture-MSphysical14968112
NUMA1Affinity Capture-MSphysical14968112
NSUN2Affinity Capture-Westernphysical17215513
PADI4Affinity Capture-Westernphysical19843866
PADI4Reconstituted Complexphysical19843866
PADI4Biochemical Activityphysical19843866
UBCAffinity Capture-Westernphysical15665273
TP53Affinity Capture-Westernphysical16740634
BARD1Affinity Capture-Westernphysical15184379
UBCAffinity Capture-MSphysical15184379
BRCA1Affinity Capture-Westernphysical15184379
BARD1Affinity Capture-Westernphysical15184379
UBCAffinity Capture-Westernphysical15184379
H2AFXAffinity Capture-MSphysical16522924
H2AFXAffinity Capture-Westernphysical16522924
CDKN2AAffinity Capture-Westernphysical16679321
CDKN2AReconstituted Complexphysical16679321
HMGA2Far Westernphysical16293633
HMGA1Far Westernphysical16293633
YY1Affinity Capture-Westernphysical16170350
YY1Reconstituted Complexphysical16170350
HIST1H3AReconstituted Complexphysical16107701
HIST2H2ACReconstituted Complexphysical16107701
HIST2H2BEReconstituted Complexphysical16107701
HIST1H4AReconstituted Complexphysical16107701
EP300Biochemical Activityphysical16107701
PMLAffinity Capture-MSphysical18212063
RARAAffinity Capture-MSphysical18212063
CTNNBL1Affinity Capture-MSphysical21385873
FANCAAffinity Capture-Westernphysical20864535
FANCCAffinity Capture-Westernphysical20864535
TFAP2AAffinity Capture-Westernphysical17318229
TFAP2AAffinity Capture-Westernphysical17318229
TFAP2AReconstituted Complexphysical17318229
TFAP2ACo-localizationphysical17318229
HDAC1Affinity Capture-Westernphysical17318229
HDAC2Affinity Capture-Westernphysical17318229
SMARCA4Affinity Capture-MSphysical20460684
DOT1LAffinity Capture-MSphysical20431927
NCLAffinity Capture-MSphysical20431927
ACACAAffinity Capture-MSphysical20431927
HNRNPMAffinity Capture-MSphysical20431927
HNRNPUAffinity Capture-MSphysical20431927
DDX21Affinity Capture-MSphysical20431927
HIST1H1CAffinity Capture-MSphysical20431927
SIRT1Affinity Capture-MSphysical20431927
YBX1Affinity Capture-MSphysical20431927
PCAffinity Capture-MSphysical20431927
CSDAAffinity Capture-MSphysical20431927
H1FXAffinity Capture-MSphysical20431927
HIST1H1AAffinity Capture-MSphysical20431927
DOT1LAffinity Capture-Westernphysical20431927
ESR1Affinity Capture-MSphysical20308691
ESR1Affinity Capture-Westernphysical20308691
CDK5RAP3Affinity Capture-MSphysical20164180
ZNF668Affinity Capture-Westernphysical21852383
ZNF668Affinity Capture-Westernphysical21852383
UBCAffinity Capture-MSphysical16196087
RYKAffinity Capture-MSphysical21875946
SMN1Affinity Capture-MSphysical19928837
CD4Affinity Capture-MSphysical15047060
YWHAQAffinity Capture-MSphysical20618440
USP36Affinity Capture-Westernphysical19679658
USP36Affinity Capture-Westernphysical19679658
USP36Reconstituted Complexphysical19679658
YWHAQAffinity Capture-MSphysical15161933
CTCFAffinity Capture-MSphysical14759373
CTCFAffinity Capture-MSphysical14759373
CTCFAffinity Capture-Westernphysical14759373
HDAC5Affinity Capture-MSphysical21081666
CDKN2AAffinity Capture-Westernphysical15989956
CDKN1AAffinity Capture-Westernphysical19221506
CDKN1AAffinity Capture-Westernphysical19221506
CDKN1AReconstituted Complexphysical19221506
CDKN1ACo-localizationphysical19221506
NOP56Affinity Capture-MSphysical12777385
CENPAAffinity Capture-MSphysical19410544
AFF1Affinity Capture-MSphysical21030982
DYRK2Affinity Capture-MSphysical19287380
TOP1Affinity Capture-MSphysical15848144
CDKN2AAffinity Capture-MSphysical15989956
SUMO1Affinity Capture-MSphysical19596686
UBCAffinity Capture-MSphysical22178446
CDK2Biochemical Activityphysical11278991
UBCAffinity Capture-MSphysical21987572