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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NRAS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4893
Official gene symbolNRAS
Full nameneuroblastoma RAS viral (v-ras) oncogene homolog
Aliases,ALPS4,N-ras,NRAS1,NS6,
Gene summaryThis is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). [provided by RefSeq]
LocationChromosome: 1   Locus: 1p13.2
Gene position115259515 - 115247078  Map Viewer
Gene orientationminus
Gene size12438 bp
Gene sequence
OMIM ID164790