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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NRAS (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000165MAPKKK cascadeTAS
GO:0000186activation of MAPKK activityTAS
GO:0007165signal transductionIEA
GO:0007173epidermal growth factor receptor signaling pathwayTAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0007265Ras protein signal transductionTAS
GO:0007411axon guidanceTAS
GO:0007596blood coagulationTAS
GO:0008284positive regulation of cell proliferationIEA
GO:0008286insulin receptor signaling pathwayTAS
GO:0008542visual learningIEA
GO:0030036actin cytoskeleton organizationIEA
GO:0032228regulation of synaptic transmission, GABAergicIEA
GO:0035022positive regulation of Rac protein signal transductionIEA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048169regulation of long-term neuronal synaptic plasticityIEA
GO:0050900leukocyte migrationTAS
GO:0051146striated muscle cell differentiationIEA
cellular_component
GO:0000139Golgi membraneIEA
GO:0005624membrane fractionIEA
GO:0005794Golgi apparatusIEA
GO:0005886plasma membraneTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0003924GTPase activityIEA
GO:0005525GTP bindingIEA
GO:0008321Ral guanyl-nucleotide exchange factor activityTAS

Protein-protein interaction details for NRAS (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
RAP1GDS1Two-hybridphysical11948427
MLLT4Affinity Capture-Westernphysical12808105
PLCE1Two-hybridphysical16169070
RAF1Affinity Capture-Westernphysical10882715
PIK3CGReconstituted Complexphysical11136978
DNAJB1Two-hybridphysical18624398
EEF1A1Two-hybridphysical18624398
SRITwo-hybridphysical18624398
RPS20Two-hybridphysical18624398
UBCAffinity Capture-MSphysical18781797
UBCAffinity Capture-MSphysical21987572