Entrez gene ID | | 5062 |
Official gene symbol | | PAK2 |
Full name | | p21 protein (Cdc42/Rac)-activated kinase 2 |
Aliases | | ,PAK65,PAKgamma, |
Gene summary | | The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q29 |
Gene position | | 196466728 - 196559518 Map Viewer |
Gene orientation | | plus |
Gene size | | 92791 bp |
Gene sequence |
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OMIM ID | | 605022 |
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