Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PAK2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5062
Official gene symbolPAK2
Full namep21 protein (Cdc42/Rac)-activated kinase 2
Aliases,PAK65,PAKgamma,
Gene summaryThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q29
Gene position196466728 - 196559518  Map Viewer
Gene orientationplus
Gene size92791 bp
Gene sequence
OMIM ID605022