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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PAK2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006468protein phosphorylationIDA
GO:0006469negative regulation of protein kinase activityTAS
GO:0006915apoptosisTAS
GO:0006921cellular component disassembly involved in apoptosisTAS
GO:0007165signal transductionTAS
GO:0007411axon guidanceTAS
GO:0016032viral reproductionTAS
GO:0018105peptidyl-serine phosphorylationIDA
GO:0031295T cell costimulationTAS
GO:0040008regulation of growthIEA
GO:0042981regulation of apoptosisTAS
GO:0044419interspecies interaction between organismsIEA
GO:0046777protein autophosphorylationIDA
GO:0050690regulation of defense response to virus by virusTAS
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDA
GO:0050852T cell receptor signaling pathwayTAS
GO:0061098positive regulation of protein tyrosine kinase activityIDA
cellular_component
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
GO:0005886plasma membraneTAS
GO:0048471perinuclear region of cytoplasmIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityTAS
GO:0004674protein serine/threonine kinase activityIDA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0019901protein kinase bindingIPI
GO:0030296protein tyrosine kinase activator activityIDA
GO:0042802identical protein bindingIPI

Protein-protein interaction details for PAK2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
GIT1Affinity Capture-MSphysical17353931
GIT2Affinity Capture-MSphysical17353931
MYH10Affinity Capture-MSphysical17353931
MCM3Affinity Capture-MSphysical17353931
SH3KBP1Affinity Capture-Westernphysical12829691
SH3KBP1Far Westernphysical12829691
CDC42Protein-peptidephysical10320322
ABI3Reconstituted Complexphysical11956071
MYL2Biochemical Activityphysical10047984
DOCK2Reconstituted Complexphysical12176041
RAC2Reconstituted Complexphysical12176041
ABL1Affinity Capture-Westernphysical11121037
ABL1Biochemical Activityphysical11121037
CDC42Reconstituted Complexphysical9822598
RAC1Reconstituted Complexphysical9535855
CDC42Reconstituted Complexphysical9535855
DSTTwo-hybridphysical20936779
EP300Two-hybridphysical20936779
RAC1Two-hybridphysical20936779
CDC42Two-hybridphysical20936779
BRAFTwo-hybridphysical20936779
UBCAffinity Capture-Westernphysical12853446