Entrez gene ID | | 50649 |
Official gene symbol | | ARHGEF4 |
Full name | | Rho guanine nucleotide exchange factor (GEF) 4 |
Aliases | | ,ASEF,ASEF1,GEF4,STM6, |
Gene summary | | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q22 |
Gene position | | 131674224 - 131804836 Map Viewer |
Gene orientation | | plus |
Gene size | | 130613 bp |
Gene sequence |
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OMIM ID | | 605216 |
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