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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ARHGEF4 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006915
apoptosis
TAS
GO:0007264
small GTPase mediated signal transduction
TAS
GO:0008624
induction of apoptosis by extracellular signals
TAS
GO:0030032
lamellipodium assembly
IMP
GO:0035023
regulation of Rho protein signal transduction
IEA
GO:0035556
intracellular signal transduction
IEA
GO:0035556
intracellular signal transduction
NAS
GO:0046847
filopodium assembly
IMP
GO:0048011
nerve growth factor receptor signaling pathway
TAS
GO:0051056
regulation of small GTPase mediated signal transduction
TAS
cellular_component
GO:0005622
intracellular
NAS
GO:0005737
cytoplasm
IEA
GO:0005829
cytosol
TAS
GO:0005886
plasma membrane
IEA
GO:0032587
ruffle membrane
IEA
GO:0042995
cell projection
IEA
molecular_function
GO:0005085
guanyl-nucleotide exchange factor activity
IEA
GO:0005085
guanyl-nucleotide exchange factor activity
IMP
GO:0005089
Rho guanyl-nucleotide exchange factor activity
IEA
GO:0005089
Rho guanyl-nucleotide exchange factor activity
NAS
GO:0005515
protein binding
IPI
GO:0019904
protein domain specific binding
IPI
GO:0030676
Rac guanyl-nucleotide exchange factor activity
IMP
Protein-protein interaction details for ARHGEF4 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
APC
Reconstituted Complex
physical
10947987
APC
Affinity Capture-Western
physical
10947987
RHOA
Reconstituted Complex
physical
10947987
RAC1
Reconstituted Complex
physical
10947987
HLA-B
Two-hybrid
physical
20936779
RAC1
Two-hybrid
physical
20936779