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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARHGEF4 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006915apoptosisTAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0030032lamellipodium assemblyIMP
GO:0035023regulation of Rho protein signal transductionIEA
GO:0035556intracellular signal transductionIEA
GO:0035556intracellular signal transductionNAS
GO:0046847filopodium assemblyIMP
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0051056regulation of small GTPase mediated signal transductionTAS
cellular_component
GO:0005622intracellularNAS
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
GO:0005886plasma membraneIEA
GO:0032587ruffle membraneIEA
GO:0042995cell projectionIEA
molecular_function
GO:0005085guanyl-nucleotide exchange factor activityIEA
GO:0005085guanyl-nucleotide exchange factor activityIMP
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA
GO:0005089Rho guanyl-nucleotide exchange factor activityNAS
GO:0005515protein bindingIPI
GO:0019904protein domain specific bindingIPI
GO:0030676Rac guanyl-nucleotide exchange factor activityIMP

Protein-protein interaction details for ARHGEF4 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
APCReconstituted Complexphysical10947987
APCAffinity Capture-Westernphysical10947987
RHOAReconstituted Complexphysical10947987
RAC1Reconstituted Complexphysical10947987
HLA-BTwo-hybridphysical20936779
RAC1Two-hybridphysical20936779