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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLR8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51311
Official gene symbolTLR8
Full nametoll-like receptor 8
Aliases,CD288,MGC119599,MGC119600,
Gene summaryThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq]
LocationChromosome: X   Locus: Xp22
Gene position12924739 - 12941288  Map Viewer
Gene orientationplus
Gene size16550 bp
Gene sequence
OMIM ID300366