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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TLR8 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006954inflammatory responseIEA
GO:0007165signal transductionIEA
GO:0007249I-kappaB kinase/NF-kappaB cascadeIDA
GO:0009615response to virusIDA
GO:0016064immunoglobulin mediated immune responseTAS
GO:0045078positive regulation of interferon-gamma biosynthetic processIDA
GO:0045087innate immune responseIEA
GO:0045087innate immune responseNAS
GO:0045087innate immune responseTAS
GO:0045089positive regulation of innate immune responseIDA
GO:0045356positive regulation of interferon-alpha biosynthetic processIDA
GO:0045359positive regulation of interferon-beta biosynthetic processIDA
GO:0045416positive regulation of interleukin-8 biosynthetic processIMP
GO:0051607defense response to virusIMP
GO:0071260cellular response to mechanical stimulusIEP
cellular_component
GO:0010008endosome membraneTAS
GO:0016020membraneIEA
GO:0016021integral to membraneIC
GO:0016021integral to membraneIEA
molecular_function
GO:0003677DNA bindingIDA
GO:0003723RNA bindingTAS
GO:0003725double-stranded RNA bindingIDA
GO:0003727single-stranded RNA bindingIDA
GO:0004872receptor activityIEA
GO:0004872receptor activityNAS
GO:0004888transmembrane signaling receptor activityIEA

Protein-protein interaction details for TLR8 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
UBCAffinity Capture-Westernphysical19850743
UBCReconstituted Complexphysical19850743