Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for TLR8 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006954
inflammatory response
IEA
GO:0007165
signal transduction
IEA
GO:0007249
I-kappaB kinase/NF-kappaB cascade
IDA
GO:0009615
response to virus
IDA
GO:0016064
immunoglobulin mediated immune response
TAS
GO:0045078
positive regulation of interferon-gamma biosynthetic process
IDA
GO:0045087
innate immune response
IEA
GO:0045087
innate immune response
NAS
GO:0045087
innate immune response
TAS
GO:0045089
positive regulation of innate immune response
IDA
GO:0045356
positive regulation of interferon-alpha biosynthetic process
IDA
GO:0045359
positive regulation of interferon-beta biosynthetic process
IDA
GO:0045416
positive regulation of interleukin-8 biosynthetic process
IMP
GO:0051607
defense response to virus
IMP
GO:0071260
cellular response to mechanical stimulus
IEP
cellular_component
GO:0010008
endosome membrane
TAS
GO:0016020
membrane
IEA
GO:0016021
integral to membrane
IC
GO:0016021
integral to membrane
IEA
molecular_function
GO:0003677
DNA binding
IDA
GO:0003723
RNA binding
TAS
GO:0003725
double-stranded RNA binding
IDA
GO:0003727
single-stranded RNA binding
IDA
GO:0004872
receptor activity
IEA
GO:0004872
receptor activity
NAS
GO:0004888
transmembrane signaling receptor activity
IEA
Protein-protein interaction details for TLR8 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
UBC
Affinity Capture-Western
physical
19850743
UBC
Reconstituted Complex
physical
19850743