Entrez gene ID | | 51567 |
Official gene symbol | | TDP2 |
Full name | | tyrosyl-DNA phosphodiesterase 2 |
Aliases | | ,AD022,EAP2,MGC111021,MGC9099,TTRAP,dJ30M3.3, |
Gene summary | | This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p22.3-p22.1 |
Gene position | | 24667115 - 24650205 Map Viewer |
Gene orientation | | minus |
Gene size | | 16911 bp |
Gene sequence |
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OMIM ID | | 605764 |
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