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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TDP2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006302 double-strand break repair IDA GO:0007166 cell surface receptor linked signaling pathway TAS cellular_component GO:0005634 nucleus IEA GO:0016605 PML body IDA molecular_function GO:0000287 magnesium ion binding TAS GO:0003714 transcription corepressor activity TAS GO:0004518 nuclease activity IEA GO:0005515 protein binding IPI GO:0016787 hydrolase activity IEA GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity IDA

Protein-protein interaction details for TDP2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID UBE2I Two-hybrid physical 14609633 SUMO1 Two-hybrid physical 14609633 ETS1 Two-hybrid physical 12743594 ETS1 Reconstituted Complex physical 12743594 ETS1 Reconstituted Complex physical 12743594 ETS1 Affinity Capture-Western physical 12743594 TNFRSF1B Affinity Capture-Western physical 10764746 TNFRSF1B Two-hybrid physical 10764746 TNFRSF8 Affinity Capture-Western physical 10764746 CD40 Two-hybrid physical 10764746 CD40 Affinity Capture-Western physical 10764746 TRAF2 Affinity Capture-Western physical 10764746 TRAF3 Affinity Capture-Western physical 10764746 TRAF5 Affinity Capture-Western physical 10764746 TRAF6 Affinity Capture-Western physical 10764746 MAPK6 Two-hybrid physical 21900206 UBC Affinity Capture-MS physical 20639865 UBC Affinity Capture-MS physical 21987572