Entrez gene ID | | 51684 |
Official gene symbol | | SUFU |
Full name | | suppressor of fused homolog (Drosophila) |
Aliases | | ,PRO1280,SUFUH,SUFUXL, |
Gene summary | | The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. |
Location | | Chromosome: 10 Locus: 10q24.32 |
Gene position | | 104263719 - 104393214 Map Viewer |
Gene orientation | | plus |
Gene size | | 129496 bp |
Gene sequence |
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OMIM ID | | 607035 |
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