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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SUFU (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51684
Official gene symbolSUFU
Full namesuppressor of fused homolog (Drosophila)
Aliases,PRO1280,SUFUH,SUFUXL,
Gene summaryThe Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
LocationChromosome: 10   Locus: 10q24.32
Gene position104263719 - 104393214  Map Viewer
Gene orientationplus
Gene size129496 bp
Gene sequence
OMIM ID607035