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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SUFU (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001501 skeletal system development TAS GO:0001843 neural tube closure IEA GO:0001947 heart looping IEA GO:0006355 regulation of transcription, DNA-dependent TAS GO:0006508 proteolysis TAS GO:0007165 signal transduction TAS GO:0007275 multicellular organismal development TAS GO:0007368 determination of left/right symmetry IEA GO:0021513 spinal cord dorsal/ventral patterning IEA GO:0043588 skin development IEA GO:0045879 negative regulation of smoothened signaling pathway IEA cellular_component GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm NAS GO:0005929 cilium IEA molecular_function GO:0003714 transcription corepressor activity TAS GO:0004871 signal transducer activity TAS GO:0005515 protein binding IPI GO:0008013 beta-catenin binding IEA GO:0008134 transcription factor binding IDA GO:0019901 protein kinase binding IPI

Protein-protein interaction details for SUFU (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID QPRT Two-hybrid physical 16189514 GLIS3 Two-hybrid physical 16189514 RCN3 Two-hybrid physical 16189514 ZNF446 Two-hybrid physical 16189514 ZNF764 Two-hybrid physical 16189514 MID1IP1 Two-hybrid physical 16189514 ZNF263 Two-hybrid physical 16189514 PEX26 Two-hybrid physical 16189514 RCN3 Affinity Capture-Western physical 16189514 PEX26 Affinity Capture-Western physical 16189514 GLI1 Affinity Capture-Western physical 10564661 GLI1 Reconstituted Complex physical 10564661 SUFU Reconstituted Complex physical 10564661 GLI2 Reconstituted Complex physical 10564661 GLI3 Reconstituted Complex physical 10564661 GLI1 Affinity Capture-Western physical 10559945 GLI1 Reconstituted Complex physical 10559945 GLI1 Reconstituted Complex physical 12426310 GLI1 Affinity Capture-Western physical 12426310 GLI1 Affinity Capture-Western physical 12426310 GLI1 Far Western physical 12426310 ZNF747 Two-hybrid physical 20211142 HDX Two-hybrid physical 20211142 SAP18 Affinity Capture-Western physical 17002296 GLIS3 Affinity Capture-Western physical 21543335 GLI1 Affinity Capture-Western physical 21543335