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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PHB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5245
Official gene symbolPHB
Full nameprohibitin
Aliases,PHB1,
Gene summaryProhibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21
Gene position47492242 - 47481420  Map Viewer
Gene orientationminus
Gene size10823 bp
Gene sequence
OMIM ID176705