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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PHB (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0006260 DNA replication IEA GO:0006355 regulation of transcription, DNA-dependent IDA GO:0007165 signal transduction TAS GO:0008285 negative regulation of cell proliferation IMP GO:0010944 negative regulation of transcription by competitive promoter binding IDA GO:0016575 histone deacetylation IDA GO:0030308 negative regulation of cell growth IMP GO:0042981 regulation of apoptosis TAS GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0050847 progesterone receptor signaling pathway IDA GO:0060766 negative regulation of androgen receptor signaling pathway IDA GO:0060766 negative regulation of androgen receptor signaling pathway IMP GO:0071354 cellular response to interleukin-6 IDA GO:2000323 negative regulation of glucocorticoid receptor signaling pathway IDA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus TAS GO:0005654 nucleoplasm IDA GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005739 mitochondrion IEA GO:0005743 mitochondrial inner membrane IEA GO:0005743 mitochondrial inner membrane TAS GO:0005887 integral to plasma membrane IDA GO:0016020 membrane IEA molecular_function GO:0005515 protein binding IPI GO:0042826 histone deacetylase binding IPI GO:0044212 transcription regulatory region DNA binding IDA

Protein-protein interaction details for PHB (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID E2F1 Reconstituted Complex physical 14637159 E2F1 Affinity Capture-Western physical 14637159 HDAC1 Reconstituted Complex physical 14637159 E2F1 Co-localization physical 14500729 TP53 Co-localization physical 14500729 TP53 Affinity Capture-Western physical 14500729 E2F1 Affinity Capture-Western physical 14500729 TP53 Reconstituted Complex physical 14500729 ANXA2 Two-hybrid physical 12628297 ANXA2 Affinity Capture-Western physical 12628297 ACTN1 Affinity Capture-Western physical 12628297 ANXA2 Reconstituted Complex physical 12628297 HDAC1 Affinity Capture-Western physical 12466959 NCOR1 Affinity Capture-Western physical 12466959 SIN3A Affinity Capture-Western physical 12466959 E2F1 Affinity Capture-Western physical 12065415 SMARCA4 Affinity Capture-Western physical 12065415 SMARCA2 Affinity Capture-Western physical 12065415 SMARCA4 Affinity Capture-Western physical 12065415 SMARCA2 Affinity Capture-Western physical 12065415 E2F1 Affinity Capture-Western physical 12065415 E2F1 Reconstituted Complex physical 10523633 E2F1 Affinity Capture-Western physical 10523633 RAF1 Affinity Capture-Western physical 10523633 RB1 Affinity Capture-Western physical 10523633 RAF1 Reconstituted Complex physical 10523633 RAF1 Reconstituted Complex physical 10523633 RBL2 Two-hybrid physical 10376528 RBL1 Reconstituted Complex physical 10376528 RB1 Reconstituted Complex physical 10376528 RBL2 Reconstituted Complex physical 10376528 RBL2 Affinity Capture-Western physical 10376528 RBL1 Affinity Capture-Western physical 10376528 RB1 Affinity Capture-Western physical 10376528 BRE Affinity Capture-MS physical 19615732 MYOD1 Affinity Capture-MS physical 20195544 CLN3 Affinity Capture-MS physical 20562859 AR Affinity Capture-Western physical 16964284 RB1 Affinity Capture-Western physical 16964284 HDAC1 Affinity Capture-Western physical 16964284 MGMT Affinity Capture-MS physical 16226712 E2F1 Affinity Capture-Western physical 15141164 E2F1 Affinity Capture-Western physical 15141164 SMARCA4 Affinity Capture-Western physical 15141164 SMARCA2 Affinity Capture-Western physical 15141164 SMARCA4 Affinity Capture-Western physical 15141164 SMARCA2 Affinity Capture-Western physical 15141164 ESR1 Reconstituted Complex physical 17932104 PHB2 Affinity Capture-Western physical 17932104 PHB2 Affinity Capture-Western physical 17932104 HDAC1 Affinity Capture-Western physical 17932104 RNF2 Affinity Capture-Western physical 17873902 RNF2 Affinity Capture-Western physical 17873902 UBC Affinity Capture-MS physical 16196087 ICT1 Affinity Capture-MS physical 20186120 CD4 Affinity Capture-MS physical 15047060 HDAC5 Affinity Capture-MS physical 21081666 SKP2 Affinity Capture-Western physical 20134482 UBC Affinity Capture-MS physical 18781797