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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLR9 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 54106 Official gene symbol TLR9 Full name toll-like receptor 9 Aliases ,CD289, Gene summary The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq] Location Chromosome: 3   Locus: 3p21.3 Gene position 52260179 - 52255098  Map Viewer Gene orientation minus Gene size 5082 bp Gene sequence >TLR9:complement(52195098..52200179):Length=5082 GGAGGTCTTGTTTCCGGAAGATGTTGCAAGGCTGTGGTGAAGGCAGGTGCAGCCTAGCCT CCTGCTCAAGCTACACCCTGGCCCTCCACGCATGAGGCCCTGCAGAACTCTGGAGATGGT GCCTACAAGGGCAGAAAAGGACAAGTCGGCAGCCGCTGTCCTGAGGGCACCAGCTGTGGT GCAGGAGCCAAGACCTGAGGGTGGAAGTGTCCTCTTAGAATGGGGAGTGCCCAGCAAGGT GTACCCGCTACTGGTGCTATCCAGAATTCCCATCTCTCCCTGCTCTCTGCCTGAGCTCTG GGCCTTAGCTCCTCCCTGGGCTTGGTAGAGGACAGGTGTGAGGCCCTCATGGGATGTAGG CTGTCTGAGAGGGGAGTGGAAAGAGGAAGGGGTGAAGGAGCTGTCTGCCATTTGACTATG CAAATGGCCTTTGACTCATGGGACCCTGTCCTCCTCACTGGGGGCAGGGTGGAGTGGAGG GGGAGCTACTAGGCTGGTATAAAAATCTTACTTCCTCTATTCTCTGAGCCGCTGCTGCCC CTGTGGGAAGGGACCTCGAGTGTGAAGCATCCTTCCCTGTAGCTGCTGTCCAGTCTGCCC GCCAGACCCTCTGGAGAAGCCCCTGCCCCCCAGCATGGTAGGACAACAGCTCTCAGTCCC CTGGGGAAGGGGATATCCTGGGAAGGGGTGGGGAAAGAAGTGGGCTTGGCAGCTGCAAGC AACAGTGACGGGTTGTCACCCACATGGCCCTGGGGACACTCACTGAATCCTGAAGACTTC AGAGCCGAAGCCCTCTTCTTTTTTCTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTG TTGCCCAGGCTGGAGTGCAGTGGCTTGATCTCAGCTCACTGCAATCTCCACCTCCCGGGT TCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTATGGCTTGCGCCACCATG CCTGGCTAATTTTGTATTTTTAGTAGAGCCAGGGTTTCTCCATGTTGGTCAGGCTGGTCT TGAACTCCAGACCTCAGGTGATCTGCCCACTTCGGCTTCCCAAACTGCTGGGATTACAGG TGTGAGCCACCGTGCCCAGCCACTGAAGCCCTCTTCTGAGCAATGAGACCCAAACCCCCA GAGGGGACGAGGAGACTGAGGCACTGATGGAGCTGGGGCTGGAGCCTGGGTTTGGGTCTC ACTGGGCCTGTAGCTTGGGGCTGGCTCTGTCTGGCACTTTGCAGGCCACCCCTCTCTCCA TCTGTTCTGACCCATAAGGCAAAGGCTCTCGGGCTAGGTGAGGCAGGCAGAGAGTGATGG AGCTGTGCAGTGCCCTCTGGCCAGGGTCCCTGGGAGGCAGCCGGCCTGGGCCATAGTGGG AGACTCTCACACCTGCCTGAATCTTGGCCGAAGGAAAAGGAAGGGGTTGTGGGGTGGCTG GTGGAGGGCAGAGAGCGGATTTCAGGGCAGCTGGAGGGGAGGGAGCCAGCTGCCACCTTG CTCAGGAGCAGGAAGGGAAAGTCGGGGAGAGACCAGGGGGGGCCGTGGGCCACCTTGCCT GGCCTGGTATAGCCAGGGATTGGTTAAGTGAAAGCTGTAGATCATAAGTCTGGATTCTAG GTCTCAGTCCTGGTTCTGAAGCCTAATTCTGAGTCCAAGACTGGGTCTGAGACTGAGTTC AGGTTCCCCACAAGCCATGGGGGATGGGAATGGGGCTTGGCAGCCAGGAAGAACTTCTGC AGGTAGGGCTTGGAGAGAGGGGTTGGAAGATGCTAGAAGATGCCCATGAAGTGGAGTGGG TGGAGGTAGAGCTGGGGGCCGGCCACTCACACAGCCCTCCCACCCCCACAGGGTTTCTGC CGCAGCGCCCTGCACCCGCTGTCTCTCCTGGTGCAGGCCATCATGCTGGCCATGACCCTG GCCCTGGGTACCTTGCCTGCCTTCCTACCCTGTGAGCTCCAGCCCCACGGCCTGGTGAAC TGCAACTGGCTGTTCCTGAAGTCTGTGCCCCACTTCTCCATGGCAGCACCCCGTGGCAAT GTCACCAGCCTTTCCTTGTCCTCCAACCGCATCCACCACCTCCATGATTCTGACTTTGCC CACCTGCCCAGCCTGCGGCATCTCAACCTCAAGTGGAACTGCCCGCCGGTTGGCCTCAGC CCCATGCACTTCCCCTGCCACATGACCATCGAGCCCAGCACCTTCTTGGCTGTGCCCACC CTGGAAGAGCTAAACCTGAGCTACAACAACATCATGACTGTGCCTGCGCTGCCCAAATCC CTCATATCCCTGTCCCTCAGCCATACCAACATCCTGATGCTAGACTCTGCCAGCCTCGCC GGCCTGCATGCCCTGCGCTTCCTATTCATGGACGGCAACTGTTATTACAAGAACCCCTGC AGGCAGGCACTGGAGGTGGCCCCGGGTGCCCTCCTTGGCCTGGGCAACCTCACCCACCTG TCACTCAAGTACAACAACCTCACTGTGGTGCCCCGCAACCTGCCTTCCAGCCTGGAGTAT CTGCTGTTGTCCTACAACCGCATCGTCAAACTGGCGCCTGAGGACCTGGCCAATCTGACC GCCCTGCGTGTGCTCGATGTGGGCGGAAATTGCCGCCGCTGCGACCACGCTCCCAACCCC TGCATGGAGTGCCCTCGTCACTTCCCCCAGCTACATCCCGATACCTTCAGCCACCTGAGC CGTCTTGAAGGCCTGGTGTTGAAGGACAGTTCTCTCTCCTGGCTGAATGCCAGTTGGTTC CGTGGGCTGGGAAACCTCCGAGTGCTGGACCTGAGTGAGAACTTCCTCTACAAATGCATC ACTAAAACCAAGGCCTTCCAGGGCCTAACACAGCTGCGCAAGCTTAACCTGTCCTTCAAT TACCAAAAGAGGGTGTCCTTTGCCCACCTGTCTCTGGCCCCTTCCTTCGGGAGCCTGGTC GCCCTGAAGGAGCTGGACATGCACGGCATCTTCTTCCGCTCACTCGATGAGACCACGCTC CGGCCACTGGCCCGCCTGCCCATGCTCCAGACTCTGCGTCTGCAGATGAACTTCATCAAC CAGGCCCAGCTCGGCATCTTCAGGGCCTTCCCTGGCCTGCGCTACGTGGACCTGTCGGAC AACCGCATCAGCGGAGCTTCGGAGCTGACAGCCACCATGGGGGAGGCAGATGGAGGGGAG AAGGTCTGGCTGCAGCCTGGGGACCTTGCTCCGGCCCCAGTGGACACTCCCAGCTCTGAA GACTTCAGGCCCAACTGCAGCACCCTCAACTTCACCTTGGATCTGTCACGGAACAACCTG GTGACCGTGCAGCCGGAGATGTTTGCCCAGCTCTCGCACCTGCAGTGCCTGCGCCTGAGC CACAACTGCATCTCGCAGGCAGTCAATGGCTCCCAGTTCCTGCCGCTGACCGGTCTGCAG GTGCTAGACCTGTCCCACAATAAGCTGGACCTCTACCACGAGCACTCATTCACGGAGCTA CCGCGACTGGAGGCCCTGGACCTCAGCTACAACAGCCAGCCCTTTGGCATGCAGGGCGTG GGCCACAACTTCAGCTTCGTGGCTCACCTGCGCACCCTGCGCCACCTCAGCCTGGCCCAC AACAACATCCACAGCCAAGTGTCCCAGCAGCTCTGCAGTACGTCGCTGCGGGCCCTGGAC TTCAGCGGCAATGCACTGGGCCATATGTGGGCCGAGGGAGACCTCTATCTGCACTTCTTC CAAGGCCTGAGCGGTTTGATCTGGCTGGACTTGTCCCAGAACCGCCTGCACACCCTCCTG CCCCAAACCCTGCGCAACCTCCCCAAGAGCCTACAGGTGCTGCGTCTCCGTGACAATTAC CTGGCCTTCTTTAAGTGGTGGAGCCTCCACTTCCTGCCCAAACTGGAAGTCCTCGACCTG GCAGGAAACCAGCTGAAGGCCCTGACCAATGGCAGCCTGCCTGCTGGCACCCGGCTCCGG AGGCTGGATGTCAGCTGCAACAGCATCAGCTTCGTGGCCCCCGGCTTCTTTTCCAAGGCC AAGGAGCTGCGAGAGCTCAACCTTAGCGCCAACGCCCTCAAGACAGTGGACCACTCCTGG TTTGGGCCCCTGGCGAGTGCCCTGCAAATACTAGATGTAAGCGCCAACCCTCTGCACTGC GCCTGTGGGGCGGCCTTTATGGACTTCCTGCTGGAGGTGCAGGCTGCCGTGCCCGGTCTG CCCAGCCGGGTGAAGTGTGGCAGTCCGGGCCAGCTCCAGGGCCTCAGCATCTTTGCACAG GACCTGCGCCTCTGCCTGGATGAGGCCCTCTCCTGGGACTGTTTCGCCCTCTCGCTGCTG GCTGTGGCTCTGGGCCTGGGTGTGCCCATGCTGCATCACCTCTGTGGCTGGGACCTCTGG TACTGCTTCCACCTGTGCCTGGCCTGGCTTCCCTGGCGGGGGCGGCAAAGTGGGCGAGAT GAGGATGCCCTGCCCTACGATGCCTTCGTGGTCTTCGACAAAACGCAGAGCGCAGTGGCA GACTGGGTGTACAACGAGCTTCGGGGGCAGCTGGAGGAGTGCCGTGGGCGCTGGGCACTC CGCCTGTGCCTGGAGGAACGCGACTGGCTGCCTGGCAAAACCCTCTTTGAGAACCTGTGG GCCTCGGTCTATGGCAGCCGCAAGACGCTGTTTGTGCTGGCCCACACGGACCGGGTCAGT GGTCTCTTGCGCGCCAGCTTCCTGCTGGCCCAGCAGCGCCTGCTGGAGGACCGCAAGGAC GTCGTGGTGCTGGTGATCCTGAGCCCTGACGGCCGCCGCTCCCGCTACGTGCGGCTGCGC CAGCGCCTCTGCCGCCAGAGTGTCCTCCTCTGGCCCCACCAGCCCAGTGGTCAGCGCAGC TTCTGGGCCCAGCTGGGCATGGCCCTGACCAGGGACAACCACCACTTCTATAACCGGAAC TTCTGCCAGGGACCCACGGCCGAATAGCCGTGAGCCGGAATCCTGCACGGTGCCACCTCC ACACTCACCTCACCTCTGCCTGCCTGGTCTGACCCTCCCCTGCTCGCCTCCCTCACCCCA CACCTGACACAGAGCAGGCACTCAATAAATGCTACCGAAGGC OMIM ID 605474