Entrez gene ID | | 5468 |
Official gene symbol | | PPARG |
Full name | | peroxisome proliferator-activated receptor gamma |
Aliases | | ,CIMT1,GLM1,NR1C3,PPARG1,PPARG2,PPARgamma, |
Gene summary | | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p25 |
Gene position | | 12329349 - 12475855 Map Viewer |
Gene orientation | | plus |
Gene size | | 146507 bp |
Gene sequence |
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OMIM ID | | 601487 |
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