Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PPARG (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0001890 placenta development ISS GO:0002674 negative regulation of acute inflammatory response IEA GO:0006351 transcription, DNA-dependent IDA GO:0006351 transcription, DNA-dependent ISS GO:0006357 regulation of transcription from RNA polymerase II promoter IEA GO:0006629 lipid metabolic process TAS GO:0006917 induction of apoptosis IDA GO:0006919 activation of caspase activity IDA GO:0007165 signal transduction IDA GO:0007507 heart development IEA GO:0007584 response to nutrient TAS GO:0008217 regulation of blood pressure IMP GO:0008285 negative regulation of cell proliferation IEA GO:0009409 response to cold IEA GO:0010467 gene expression TAS GO:0010745 negative regulation of macrophage derived foam cell differentiation IC GO:0010745 negative regulation of macrophage derived foam cell differentiation IDA GO:0010871 negative regulation of receptor biosynthetic process IDA GO:0010887 negative regulation of cholesterol storage IDA GO:0010891 negative regulation of sequestering of triglyceride IDA GO:0014070 response to organic cyclic compound IEA GO:0015909 long-chain fatty acid transport ISS GO:0019216 regulation of lipid metabolic process IEA GO:0030224 monocyte differentiation IDA GO:0030308 negative regulation of cell growth IEA GO:0030522 intracellular receptor mediated signaling pathway IDA GO:0030855 epithelial cell differentiation ISS GO:0031000 response to caffeine IEA GO:0031100 organ regeneration IEA GO:0032869 cellular response to insulin stimulus IMP GO:0033189 response to vitamin A IEA GO:0033993 response to lipid ISS GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0042493 response to drug IEA GO:0042593 glucose homeostasis IMP GO:0042953 lipoprotein transport IDA GO:0043627 response to estrogen stimulus IEA GO:0045087 innate immune response TAS GO:0045165 cell fate commitment ISS GO:0045598 regulation of fat cell differentiation IEA GO:0045600 positive regulation of fat cell differentiation ISS GO:0045713 low-density lipoprotein particle receptor biosynthetic process IDA GO:0045892 negative regulation of transcription, DNA-dependent ISS GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046321 positive regulation of fatty acid oxidation IEA GO:0048469 cell maturation IDA GO:0048714 positive regulation of oligodendrocyte differentiation IEA GO:0050872 white fat cell differentiation ISS GO:0050872 white fat cell differentiation TAS GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0051974 negative regulation of telomerase activity IEA GO:0055088 lipid homeostasis TAS GO:0055098 response to low-density lipoprotein particle stimulus IDA GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway IMP GO:0060694 regulation of cholesterol transporter activity IC cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005829 cytosol IEA GO:0005829 cytosol ISS molecular_function GO:0003677 DNA binding IEA GO:0003677 DNA binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003700 sequence-specific DNA binding transcription factor activity ISS GO:0003707 steroid hormone receptor activity IEA GO:0004872 receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity IDA GO:0004879 ligand-dependent nuclear receptor activity IEA GO:0004955 prostaglandin receptor activity TAS GO:0005515 protein binding IPI GO:0008144 drug binding IDA GO:0008270 zinc ion binding IEA GO:0019899 enzyme binding IPI GO:0033613 activating transcription factor binding IDA GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0044212 transcription regulatory region DNA binding ISS GO:0046872 metal ion binding IEA GO:0046965 retinoid X receptor binding IDA GO:0050544 arachidonic acid binding ISS

Protein-protein interaction details for PPARG (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NCOA4 Two-hybrid physical 10347167 GADD45G Reconstituted Complex physical 10872826 DNTTIP2 Reconstituted Complex physical 15047147 PPARGC1A Reconstituted Complex physical 14636573 PPARGC1A Reconstituted Complex physical 14636573 HDAC3 Reconstituted Complex physical 12943985 HDAC4 Reconstituted Complex physical 12943985 RB1 Affinity Capture-Western physical 12479814 HDAC3 Affinity Capture-Western physical 12479814 RB1 Reconstituted Complex physical 12479814 HDAC3 Reconstituted Complex physical 12479814 RB1 Reconstituted Complex physical 12479814 HDAC3 Affinity Capture-Western physical 12479814 EP300 Reconstituted Complex physical 12479814 EDF1 Reconstituted Complex physical 12040021 EDF1 Two-hybrid physical 12040021 FABP1 Two-hybrid physical 11226238 NR0B2 Affinity Capture-Western physical 11696534 NR0B2 Reconstituted Complex physical 11696534 SVIL Two-hybrid physical 11792840 NRIP1 Reconstituted Complex physical 9626662 NFE2L2 Reconstituted Complex physical 10930400 POU1F1 Reconstituted Complex physical 11891224 CREBBP Reconstituted Complex physical 10848596 NCOA2 Two-hybrid physical 10944516 EP300 Two-hybrid physical 10944516 MED1 Two-hybrid physical 10944516 NCOA3 Two-hybrid physical 10944516 MED1 Reconstituted Complex physical 10944516 EP300 Reconstituted Complex physical 10944516 NCOA2 Reconstituted Complex physical 10944516 NCOA3 Reconstituted Complex physical 10944516 NCOA4 Reconstituted Complex physical 10347167 RXRA Co-purification physical 7838715 RXRA Reconstituted Complex physical 10854698 RXRA Co-crystal Structure physical 10882139 MED24 Reconstituted Complex physical 9653119 PPARGC1A Reconstituted Complex physical 10558993 MSX2 Two-hybrid physical 20211142 PML Two-hybrid physical 20211142 ZBTB5 Two-hybrid physical 20211142 NR2E3 Two-hybrid physical 20211142 MAFF Two-hybrid physical 20211142 ZBTB20 Two-hybrid physical 20211142 ZBTB3 Two-hybrid physical 20211142 ZNF496 Two-hybrid physical 20211142 ZBTB9 Two-hybrid physical 20211142 ZSCAN1 Two-hybrid physical 20211142 PIAS1 Affinity Capture-Western physical 16127449 PIAS1 Co-localization physical 16127449 NCOR1 Two-hybrid physical 16127449 NCOR1 Co-localization physical 15681609 NCOR2 Co-localization physical 15681609 NCOR1 Co-localization physical 15681609 NCOR2 Co-localization physical 15681609 HMGA1 Reconstituted Complex physical 18310298 SP1 Reconstituted Complex physical 18310298 TFAP2A Reconstituted Complex physical 18310298 CEBPB Reconstituted Complex physical 18310298 MED1 FRET physical 11500849 ZNHIT3 FRET physical 11500849 TRIP4 FRET physical 11500849 JMJD1C FRET physical 11500849 NFKBIB FRET physical 11500849 NRIP1 FRET physical 11500849 SERPINH1 FRET physical 11500849 NCOA1 FRET physical 11500849 TRIM24 FRET physical 11500849 NCOA2 FRET physical 11500849 NCOA3 FRET physical 11500849 EP300 FRET physical 11500849 NCOA1 Reconstituted Complex physical 11027271 NCOA3 Reconstituted Complex physical 11027271 GRIP1 Reconstituted Complex physical 11027271 MED1 Reconstituted Complex physical 11027271 MED1 Two-hybrid physical 10935544 HMGA1 Two-hybrid physical 10428834 MED1 Reconstituted Complex physical 10037764 KAT5 Reconstituted Complex physical 18096664 C1orf103 Reconstituted Complex physical 17455211 NLK Co-purification physical 17952062 NLK Affinity Capture-Western physical 17952062 CHD7 Reconstituted Complex physical 17952062 SETDB1 Reconstituted Complex physical 17952062 NLK Reconstituted Complex physical 17952062 SP1 Affinity Capture-Western physical 20360975 SP1 Affinity Capture-Western physical 20360975 HDAC1 Reconstituted Complex physical 16407282 HDAC1 Affinity Capture-Western physical 16407282 UBC Affinity Capture-Western physical 19951908 HDAC1 Affinity Capture-RNA physical 21151932 MECP2 Affinity Capture-RNA physical 21151932 EZH2 Affinity Capture-RNA physical 21151932 MED1 Two-hybrid physical 15604093 NCOR2 Two-hybrid physical 15604093 NCOA3 Two-hybrid physical 15604093 NCOA6 Two-hybrid physical 15604093 NR0B1 Two-hybrid physical 15604093 COPS5 Two-hybrid physical 15604093 FHOD1 Two-hybrid physical 15604093 KIF1A Two-hybrid physical 15604093 RXRB Two-hybrid physical 15604093 NCOR2 Affinity Capture-Western physical 20364085 SUMO1 Affinity Capture-Western physical 19625650 EP300 Affinity Capture-Western physical 10075656 EP300 Reconstituted Complex physical 10075656 EP300 Two-hybrid physical 10075656 ROBO4 Reconstituted Complex physical 14761960