Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPP1CA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5499 Official gene symbol PPP1CA Full name protein phosphatase 1, catalytic subunit, alpha isozyme Aliases ,MGC15877,MGC1674,PP-1A,PP1alpha,PPP1A, Gene summary The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 11   Locus: 11q13 Gene position 67169376 - 67165652  Map Viewer Gene orientation minus Gene size 3725 bp Gene sequence >PPP1CA:complement(12471447..12475171):Length=3725 GCGGGGCCGCGGGCCGGGGGCGGACTGGGGCGGGCGGAAGGAGAGCCAGGCCGGAAGGAG GCTGCCGGAGGGCGGGAGGCAGGAGCGGGCCAGGAGCTGCTGGGCTGGAGCGGCGGCGCC GCCATGTCCGACAGCGAGAAGCTCAACCTGGACTCGATCATCGGGCGCCTGCTGGAAGGT TGGTCGGGGCGGGGGAGGCCCGCGTCCGCCGCGCCCTGGCCCCCTGCCCGGCCCGGAAGT GGCGCGCGGGCGGGCCCCCGGGGCCAGCTTAGACTGGGCGGGGACGGGCAGCGAGGTTCC GTGGCCGCAGCTGCCCCCCCGCGGACGCGCCTGAGAGGTCCGGGGCCAGCTCCGACGCGC GGAGCAGCTCCCCCCCTCTCCCGGGCTGGGGGCGCACGGGTTGCCTGGGCTCTTGGGGCG AGGGAGAAACCCGGGAAGCCCGGTCCAGGAAGGGGTCCTGCGCTGTGAGGTTTTTGGTGG CAGCCCCCTGCGCACGACAGTCGCCTCCCGAGGCGCTGAGGGTAGCTGGGGGCTTCCCCT GGGAGGCTTGAGGCCGCGGTCCCGGGAGGCTCAGCAGCAACAGCTGCCTGTGGGCAAGGA GGGGCCGAGGAGGCCTAGGCGCCCCCGGAGGTATCCATGGGGCCACCCGTGTCGCCCACC CTCCTCCTGTCAGGGTCCAGGGTCCTGACACCCCATTGCGCCCCAGTGCAGGGCTCGCGG CCTGGCAAGAATGTACAGCTGACAGAGAACGAGATCCGCGGTCTGTGCCTGAAATCCCGG GAGATTTTTCTGAGCCAGCCCATTCTTCTGGAGCTGGAGGCACCCCTCAAGATCTGCGGT GAGCCCCCGGCCCAGGTCCCCTTGCCTTCCTAAAAGTGGCACTGGACCCCACAGAGTTCC TGGAGCCCTCCTCCCTTGAGCGCAGTCCTGGCCCTGGGTTCAGGTCTAGACCTTGCATCT AGCTTACCCGGTTCCCTGGGTCACAGGTGACATACACGGCCAGTACTACGACCTTCTGCG ACTATTTGAGTATGGCGGTTTCCCTCCCGAGAGCAACTACCTCTTTCTGGGGGACTATGT GGACAGGGGCAAGCAGTCCTTGGAGACCATCTGCCTGCTGCTGGCCTATAAGATCAAGTA CCCCGAGAACTTCTTCCTGCTCCGTGGGAACCACGAGTGTGCCAGCATCAACCGCATCTA TGGTTTCTACGATGAGTGTGAGTGGTCTGAGCGTCTGGGGCTGCCCGGGTCCTGAACCGC ACTCTTTGCCATTCAGTGGGACCTTCACATTGGCCTGATATCTGACAGACACTTGATAGA CTGTGCGCTCCACGAAGGCGGGGCCCAGGTCCGTTCTCGTGCCTGCCCTGCCCCTCCTGG CATGGGGTCTGGGGAATGGTTGCTGACTGAAGGGCTGCCCGGATTCTAGTGCTTTCCCCC AGGGCCCTGCCTGGTGACACTCCCCCTACATTTGCTACTAAGCACTTAGGATGTTTGCAG ATGGGCTCTGCTGTCCAGAAGCTGAGATAAACCAGACCTGGACTTGGCCCGGCTCATGGG TGGGGGCATGCGAGGAGTGCCAACCCTGAGGCTGGTCCAGATTGGAACTTAGTTTCCAGT GGACTCGGGTGCTTTAGAATTACTTCTGGCAGGAGGCCGAGGCGGGAAGATCCCTTGGAC CCAGAAGCTCCAAGTTACAGTGAGCTATGATCTTGCCACTGCACTCCAGCCTGGGTGACA GAGCAAGACCCTGTTTCTTTACTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTA GAGTGCAATGGTGTGATCTCGGCTCACCACAACCTCCGTCTCCTGGGTTCAAGCGATTCT CCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCACGCCTGGCTGATT TTTTTGTATTTTAGTAGAGACGAGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTTCT GACCTCAGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTCTTAGCCA CTGCGCCTGGCCAGATCCTGTCTTCTTTAATTAAAATAAAAAGTAACTAGAATTGCTCCT GGAAGGCTGACAGGTGGCAGGGGTGGGGGGTGGTTTGCATCGGTGCCTGACTCTCTCCTC CCAGCCACGGCTGAATAGCCCAGGGACCCTGGCTGAGGGTGGGGTAGGCAGGCACCTCAC AGCCACCTCCCCCTGGGCAGGCAAGAGACGCTACAACATCAAACTGTGGAAAACCTTCAC TGACTGCTTCAACTGCCTGCCCATCGCGGCCATAGTGGACGAAAAGATCTTCTGCTGCCA CGGAGGTGAGGGAGGGGATGGCTGGGGAGGAGGAGCACTGGCCGCATCCCTCAGCACCCG GCAGCTCTCCTTAGGTCTCATCTGGGAAGTCACTCCTTCCAGGAAGTGTCCCCCATACCC CACTGTGCTGGGCTGCACTCACTTCCTTGATGTGTGTCCTACATGGAGTGGGCTTGTCTC CTTTCTCCCGGGAGCTCTGTGCTCCTGAGGGCAGGGATGCCTTTGTGCCTGTTTGGGAAC TTGAAAAAGCTGAGGGGAAGGGGATGACTTCTGCCTGTCTAGGCGCCCAGGAGACCAGTG GCGGGACCAGGAGGGTGGTGGGAAAGGTGGGGTTCATTGGCCAAGGCTTCCTGGAGGGAG GATGTCCTTGTTTGAGGAAGTGACCTTCCCCCGGCCCCCCAGGCCTGTCCCCGGACCTGC AGTCTATGGAGCAGATTCGGCGGATCATGCGGCCCACAGATGTGCCTGACCAGGGCCTGC TGTGTGACCTGCTGTGGTCTGACCCTGACAAGGACGTGCAGGGCTGGGGCGAGAACGACC GTGGCGTCTCTTTTACCTTTGGAGCCGAGGTGGTGGCCAAGTTCCTCCACAAGCACGACT TGGACCTCATCTGCCGAGCACACCAGGTGGGCTGGTGGCTCCGGCCTGCGGCAGGGGAAG GGGAGGGCCGTGCCTGCGCTCGGGACTGACTGCTCCCATCCTCGCCCAGGTGGTAGAAGA CGGCTACGAGTTCTTTGCCAAGCGGCAGCTGGTGACACTTTTCTCAGCTCCCAACTACTG TGGCGAGTTTGACAATGCTGGCGCCATGATGAGTGTGGACGAGACCCTCATGTGCTCTTT CCAGGTGAGTGTGGGGAAGAAAGGAGCCGCTAGGCCCTGTGGCTCAGCCCCATGAGCCTG ACCAACACTGTCTCTTTTAGATCCTCAAGCCCGCCGACAAGAACAAGGGGAAGTACGGGC AGTTCAGTGGCCTGAACCCTGGAGGCCGACCCATCACCCCACCCCGCAATTCCGCCAAAG CCAAGAAATAGCCCCCGCACACCACCCTGTGCCCCAGATGATGGATTGATTGTACAGAAA TCATGCTGCCATGCTGGGGGGGGGTCACCCCGACCCCTCAGGCCCACCTGTCACGGGGAA CATGGAGCCTTGGTGTATTTTTCTTTTCTTTTTTTAATGAATCAATAGCAGCGTCCAGTC CCCCAGGGCTGCTTCCTGCCTGCACCTGCGGTGACTGTGAGCAGGATCCTGGGGCCGAGG CTGCAGCTCAGGGCAACGGCAGGCCAGGTCGTGGGTCTCCAGCCGTGCTTGGCCTCAGGG CTGGCAGCCGGATCCTGGGGCAACCCATCTGGTCTCTTGAATAAAGGTCAAAGCTGGATT CTCGC OMIM ID 176875