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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PPP1CA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0005975 carbohydrate metabolic process IEA GO:0005977 glycogen metabolic process IEA GO:0005979 regulation of glycogen biosynthetic process IEA GO:0005981 regulation of glycogen catabolic process IEA GO:0006470 protein dephosphorylation IEA GO:0006470 protein dephosphorylation TAS GO:0006629 lipid metabolic process TAS GO:0007049 cell cycle IEA GO:0019433 triglyceride catabolic process TAS GO:0030324 lung development IEA GO:0048754 branching morphogenesis of a tube IEA GO:0051301 cell division IEA cellular_component GO:0000164 protein phosphatase type 1 complex IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm IEA GO:0005730 nucleolus IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol IEA GO:0005829 cytosol TAS GO:0042587 glycogen granule IEA GO:0043005 neuron projection IEA GO:0043197 dendritic spine IEA GO:0043204 perikaryon IEA GO:0070688 MLL5-L complex IDA GO:0072357 PTW/PP1 phosphatase complex IDA molecular_function GO:0004721 phosphoprotein phosphatase activity IEA GO:0004722 protein serine/threonine phosphatase activity IEA GO:0004722 protein serine/threonine phosphatase activity TAS GO:0005515 protein binding IPI GO:0008599 protein phosphatase type 1 regulator activity TAS GO:0016787 hydrolase activity IEA GO:0043021 ribonucleoprotein binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for PPP1CA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PHACTR3 Two-hybrid physical 12925532 BRCA1 Reconstituted Complex physical 12438214 BRCA1 Affinity Capture-Western physical 12438214 PHACTR1 Affinity Capture-Western physical 15107502 PHACTR1 Two-hybrid physical 15107502 PHACTR1 Affinity Capture-Western physical 15107502 ACTA1 Affinity Capture-Western physical 15107502 PHACTR3 Affinity Capture-Western physical 12925532 PHACTR3 Far Western physical 12925532 EED Reconstituted Complex physical 12788942 PPP1R8 Reconstituted Complex physical 12788942 PPP1R15A Affinity Capture-Western physical 12724406 AKAP11 Affinity Capture-Western physical 12147701 GSK3B Affinity Capture-Western physical 12147701 AKAP11 Affinity Capture-Western physical 12147701 PPP1R15A Affinity Capture-Western physical 12016208 SMARCB1 Reconstituted Complex physical 12016208 SMARCB1 Affinity Capture-Western physical 12016208 SMARCB1 Phenotypic Enhancement genetic 12016208 PPP1R15A Affinity Capture-Western physical 11564868 PPP1R15A Phenotypic Suppression genetic 11564868 PPP1R9B Affinity Capture-Western physical 10194355 PPP1R9B Reconstituted Complex physical 10194355 RYR2 Co-fractionation physical 10830164 EIF2AK2 Affinity Capture-Western physical 12138106 EIF2AK2 Reconstituted Complex physical 12138106 EIF2AK2 Biochemical Activity physical 12138106 KCNQ1 Affinity Capture-Western physical 11799244 KCNQ1 Reconstituted Complex physical 11799244 BCL2L1 Affinity Capture-Western physical 12115603 BCL2L2 Affinity Capture-Western physical 12115603 BCL2L1 Reconstituted Complex physical 12115603 BCL2L2 Reconstituted Complex physical 12115603 HSPA8 Affinity Capture-Western physical 9269769 AKAP11 Reconstituted Complex physical 10209101 PPP1R10 Reconstituted Complex physical 10637318 NOC2L Reconstituted Complex physical 10637318 RRP1B Reconstituted Complex physical 10637318 PPP1R8 Reconstituted Complex physical 10637318 HCFC1 Reconstituted Complex physical 10637318 HCFC1 Affinity Capture-Western physical 10637318 LMTK2 Reconstituted Complex physical 12393858 LMTK2 Affinity Capture-Western physical 12393858 LMTK2 Two-hybrid physical 12393858 LMTK2 Biochemical Activity physical 12393858 CDC5L Affinity Capture-MS physical 11101529 CDC5L Co-purification physical 11101529 RRP1B Affinity Capture-MS physical 19710015 BRCA1 Affinity Capture-Western physical 17511879 RUVBL2 Affinity Capture-MS physical 17643375 RPAP2 Affinity Capture-MS physical 17643375 RPAP3 Affinity Capture-MS physical 17643375 NCOR1 Affinity Capture-Western physical 12410313 IKBKB Affinity Capture-Western physical 18362886 CUEDC2 Affinity Capture-Western physical 18362886 CCDC6 Co-localization physical 20498639 CREB1 Biochemical Activity physical 20498639 TRIM28 Affinity Capture-Western physical 20424263 TRIM28 Affinity Capture-Western physical 20424263 TRIM28 Reconstituted Complex physical 20424263 TRIM28 Biochemical Activity physical 20424263 TRIM28 Co-localization physical 20424263 PPP1R8 Affinity Capture-Western physical 20671031 WDR82 Affinity Capture-MS physical 20516061 WDR82 Affinity Capture-Western physical 20516061 WDR82 Affinity Capture-Western physical 20516061 TOX4 Affinity Capture-Western physical 20516061 PPP1R10 Affinity Capture-Western physical 20516061 TOX4 Affinity Capture-Western physical 20516061 PPP1R10 Affinity Capture-Western physical 20516061 PPP1R8 Affinity Capture-Western physical 20516061 PPP1R10 Affinity Capture-MS physical 20516061 TOX4 Affinity Capture-MS physical 20516061 TOX4 Reconstituted Complex physical 20516061 PPP1R10 Reconstituted Complex physical 20516061 WDR82 Reconstituted Complex physical 20516061 WDR82 Reconstituted Complex physical 20516061 MYC Affinity Capture-MS physical 17314511 HDAC5 Affinity Capture-MS physical 21081666 STAU1 Affinity Capture-Western physical 15303970 UBC Affinity Capture-MS physical 18781797 NONO Affinity Capture-Western physical 21566083 SFPQ Affinity Capture-Western physical 21566083 NONO Affinity Capture-Western physical 21566083 SFPQ Affinity Capture-Western physical 21566083 NONO Reconstituted Complex physical 21566083 NONO Biochemical Activity physical 21566083 SFPQ Biochemical Activity physical 21566083