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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP2K6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5608
Official gene symbolMAP2K6
Full namemitogen-activated protein kinase kinase 6
Aliases,MAPKK6,MEK6,MKK6,PRKMK6,SAPKK3,
Gene summaryThis gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q24.3
Gene position67410838 - 67538470  Map Viewer
Gene orientationplus
Gene size127633 bp
Gene sequence
OMIM ID601254