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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MAP2K6 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006975 DNA damage induced protein phosphorylation TAS GO:0007050 cell cycle arrest TAS GO:0007165 signal transduction TAS GO:0008063 Toll signaling pathway TAS GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0042493 response to drug IEA GO:0042692 muscle cell differentiation TAS GO:0043065 positive regulation of apoptosis IEA GO:0045087 innate immune response TAS GO:0051149 positive regulation of muscle cell differentiation TAS GO:0051403 stress-activated MAPK cascade TAS GO:0060048 cardiac muscle contraction IEA GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS cellular_component GO:0005654 nucleoplasm TAS GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IEA GO:0004708 MAP kinase kinase activity TAS GO:0004713 protein tyrosine kinase activity IEA GO:0005524 ATP binding IEA GO:0019901 protein kinase binding IPI

Protein-protein interaction details for MAP2K6 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MAP3K7 Biochemical Activity physical 14633987 MAPK14 Biochemical Activity physical 12697810 SMAD7 Affinity Capture-Western physical 12589052 MAP3K7 Biochemical Activity physical 11460167 MAP3K5 Reconstituted Complex physical 12820963 MAPK14 Biochemical Activity physical 8622669 MAPK14 Biochemical Activity physical 8626699 MAP3K4 Biochemical Activity physical 9841871 MAPK14 Biochemical Activity physical 11279118 TAOK2 Biochemical Activity physical 11279118 TAOK2 Affinity Capture-Western physical 11279118 PLCB2 Affinity Capture-Western physical 12054652 MAP3K5 Biochemical Activity physical 11689443 MAP3K7 Biochemical Activity physical 10094049 NPHS1 Phenotypic Suppression genetic 11562357 MAP2K3 Phenotypic Enhancement genetic 11562357 MAP3K7 Biochemical Activity physical 10838074 MAP3K7 Biochemical Activity physical 20932476 UBC Affinity Capture-Western physical 19737936 MAP3K7 Biochemical Activity physical 19675569 PTEN Affinity Capture-MS physical 15717329 MAPK14 Affinity Capture-Western physical 17255949